| Full name: shisa family member 2 | Alias Symbol: bA398O19.2|PRO28631|WGAR9166|hShisa | ||
| Type: protein-coding gene | Cytoband: 13q12.13 | ||
| Entrez ID: 387914 | HGNC ID: HGNC:20366 | Ensembl Gene: ENSG00000180730 | OMIM ID: 617324 |
| Drug and gene relationship at DGIdb | |||
Expression of SHISA2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SHISA2 | 387914 | 230493_at | 1.8866 | 0.1928 | |
| GSE26886 | SHISA2 | 387914 | 230493_at | 3.7912 | 0.0000 | |
| GSE45670 | SHISA2 | 387914 | 230493_at | 1.7150 | 0.0309 | |
| GSE53622 | SHISA2 | 387914 | 107667 | 3.6576 | 0.0000 | |
| GSE53624 | SHISA2 | 387914 | 107667 | 3.6490 | 0.0000 | |
| GSE63941 | SHISA2 | 387914 | 230493_at | 0.6724 | 0.5769 | |
| GSE77861 | SHISA2 | 387914 | 230493_at | 2.2775 | 0.0076 | |
| SRP007169 | SHISA2 | 387914 | RNAseq | 4.8261 | 0.0004 | |
| SRP008496 | SHISA2 | 387914 | RNAseq | 4.0927 | 0.0000 | |
| SRP064894 | SHISA2 | 387914 | RNAseq | 3.4585 | 0.0000 | |
| SRP133303 | SHISA2 | 387914 | RNAseq | 2.3619 | 0.0000 | |
| SRP159526 | SHISA2 | 387914 | RNAseq | 6.5520 | 0.0000 | |
| SRP193095 | SHISA2 | 387914 | RNAseq | 1.8981 | 0.0000 | |
| SRP219564 | SHISA2 | 387914 | RNAseq | 1.5582 | 0.0002 | |
| TCGA | SHISA2 | 387914 | RNAseq | 0.8484 | 0.0094 |
Upregulated datasets: 12; Downregulated datasets: 0.
Survival by SHISA2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SHISA2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SHISA2 | 387914 | 1 | 12 | 17 | |
| GSE20123 | SHISA2 | 387914 | 1 | 11 | 18 | |
| GSE43470 | SHISA2 | 387914 | 2 | 12 | 29 | |
| GSE46452 | SHISA2 | 387914 | 0 | 33 | 26 | |
| GSE47630 | SHISA2 | 387914 | 3 | 26 | 11 | |
| GSE54993 | SHISA2 | 387914 | 11 | 2 | 57 | |
| GSE54994 | SHISA2 | 387914 | 1 | 13 | 39 | |
| GSE60625 | SHISA2 | 387914 | 0 | 3 | 8 | |
| GSE74703 | SHISA2 | 387914 | 2 | 9 | 25 | |
| GSE74704 | SHISA2 | 387914 | 0 | 9 | 11 | |
| TCGA | SHISA2 | 387914 | 6 | 44 | 46 |
Total number of gains: 27; Total number of losses: 174; Total Number of normals: 287.
Somatic mutations of SHISA2:
Generating mutation plots.
Highly correlated genes for SHISA2:
Showing top 20/1313 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SHISA2 | FZD2 | 0.772811 | 5 | 0 | 5 |
| SHISA2 | PXDN | 0.772183 | 6 | 0 | 6 |
| SHISA2 | CD276 | 0.762033 | 4 | 0 | 4 |
| SHISA2 | NCAPH | 0.749701 | 4 | 0 | 4 |
| SHISA2 | LARP6 | 0.744964 | 6 | 0 | 6 |
| SHISA2 | UBE2T | 0.741847 | 6 | 0 | 6 |
| SHISA2 | GCLC | 0.741241 | 3 | 0 | 3 |
| SHISA2 | KHSRP | 0.735709 | 3 | 0 | 3 |
| SHISA2 | SNRPE | 0.733415 | 5 | 0 | 5 |
| SHISA2 | RANBP1 | 0.731575 | 6 | 0 | 6 |
| SHISA2 | PRR5L | 0.730304 | 6 | 0 | 5 |
| SHISA2 | UBE2S | 0.728212 | 4 | 0 | 4 |
| SHISA2 | CDK4 | 0.727104 | 6 | 0 | 6 |
| SHISA2 | CDH11 | 0.725837 | 7 | 0 | 7 |
| SHISA2 | RAI14 | 0.72395 | 6 | 0 | 6 |
| SHISA2 | NUAK1 | 0.72175 | 6 | 0 | 6 |
| SHISA2 | TBCE | 0.721371 | 3 | 0 | 3 |
| SHISA2 | NOX4 | 0.715877 | 5 | 0 | 5 |
| SHISA2 | WDR54 | 0.715373 | 6 | 0 | 6 |
| SHISA2 | MTERF3 | 0.714467 | 3 | 0 | 3 |
For details and further investigation, click here
