| Full name: olfactory receptor family 7 subfamily D member 4 | Alias Symbol: hg105|OR19-B | ||
| Type: protein-coding gene | Cytoband: 19p13.2 | ||
| Entrez ID: 125958 | HGNC ID: HGNC:8380 | Ensembl Gene: ENSG00000174667 | OMIM ID: 611538 |
| Drug and gene relationship at DGIdb | |||
OR7D4 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04740 | Olfactory transduction |
Expression of OR7D4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | OR7D4 | 125958 | 55651 | 0.4542 | 0.0000 | |
| GSE53624 | OR7D4 | 125958 | 55651 | 0.5211 | 0.0000 | |
| GSE97050 | OR7D4 | 125958 | A_23_P130547 | -0.0148 | 0.9537 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by OR7D4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OR7D4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OR7D4 | 125958 | 4 | 2 | 24 | |
| GSE20123 | OR7D4 | 125958 | 3 | 1 | 26 | |
| GSE43470 | OR7D4 | 125958 | 3 | 5 | 35 | |
| GSE46452 | OR7D4 | 125958 | 47 | 1 | 11 | |
| GSE47630 | OR7D4 | 125958 | 5 | 7 | 28 | |
| GSE54993 | OR7D4 | 125958 | 16 | 3 | 51 | |
| GSE54994 | OR7D4 | 125958 | 6 | 14 | 33 | |
| GSE60625 | OR7D4 | 125958 | 9 | 0 | 2 | |
| GSE74703 | OR7D4 | 125958 | 3 | 4 | 29 | |
| GSE74704 | OR7D4 | 125958 | 0 | 1 | 19 | |
| TCGA | OR7D4 | 125958 | 10 | 19 | 67 |
Total number of gains: 106; Total number of losses: 57; Total Number of normals: 325.
Somatic mutations of OR7D4:
Generating mutation plots.
Highly correlated genes for OR7D4:
Showing top 20/51 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OR7D4 | MYLK2 | 0.761006 | 3 | 0 | 3 |
| OR7D4 | PNMA3 | 0.747474 | 3 | 0 | 3 |
| OR7D4 | KLK3 | 0.747178 | 3 | 0 | 3 |
| OR7D4 | LRFN4 | 0.737638 | 3 | 0 | 3 |
| OR7D4 | MS4A18 | 0.712767 | 3 | 0 | 3 |
| OR7D4 | OR2A5 | 0.712056 | 3 | 0 | 3 |
| OR7D4 | CBX8 | 0.711672 | 3 | 0 | 3 |
| OR7D4 | OR2T1 | 0.700858 | 3 | 0 | 3 |
| OR7D4 | DEFB121 | 0.700131 | 3 | 0 | 3 |
| OR7D4 | KIF19 | 0.695519 | 3 | 0 | 3 |
| OR7D4 | CIB3 | 0.693505 | 3 | 0 | 3 |
| OR7D4 | NPM2 | 0.692839 | 3 | 0 | 3 |
| OR7D4 | FOXL2 | 0.688317 | 3 | 0 | 3 |
| OR7D4 | PSMB11 | 0.687683 | 3 | 0 | 3 |
| OR7D4 | OR10A7 | 0.686268 | 3 | 0 | 3 |
| OR7D4 | OR2AG2 | 0.685785 | 4 | 0 | 4 |
| OR7D4 | COPS7B | 0.68494 | 3 | 0 | 3 |
| OR7D4 | TMEM179 | 0.682433 | 3 | 0 | 3 |
| OR7D4 | CYP11B1 | 0.679475 | 3 | 0 | 3 |
| OR7D4 | DMP1 | 0.671796 | 3 | 0 | 3 |
For details and further investigation, click here
