| Full name: FRY like transcription coactivator | Alias Symbol: DKFZp686E205|AF4p12|MOR2 | ||
| Type: protein-coding gene | Cytoband: 4p11 | ||
| Entrez ID: 285527 | HGNC ID: HGNC:29127 | Ensembl Gene: ENSG00000075539 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of FRYL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FRYL | 285527 | 212548_s_at | -0.0253 | 0.9538 | |
| GSE20347 | FRYL | 285527 | 212548_s_at | -0.2762 | 0.0230 | |
| GSE23400 | FRYL | 285527 | 212548_s_at | -0.0504 | 0.4703 | |
| GSE26886 | FRYL | 285527 | 212548_s_at | 0.3415 | 0.1906 | |
| GSE29001 | FRYL | 285527 | 212548_s_at | -0.0892 | 0.7355 | |
| GSE38129 | FRYL | 285527 | 212548_s_at | -0.2652 | 0.0177 | |
| GSE45670 | FRYL | 285527 | 212548_s_at | 0.0444 | 0.8636 | |
| GSE53622 | FRYL | 285527 | 8680 | 0.2892 | 0.0000 | |
| GSE53624 | FRYL | 285527 | 8680 | 0.2049 | 0.0001 | |
| GSE63941 | FRYL | 285527 | 212548_s_at | -0.4585 | 0.3377 | |
| GSE77861 | FRYL | 285527 | 212548_s_at | -0.1509 | 0.6341 | |
| GSE97050 | FRYL | 285527 | A_33_P3840630 | -0.0060 | 0.9846 | |
| SRP007169 | FRYL | 285527 | RNAseq | 0.1780 | 0.5872 | |
| SRP008496 | FRYL | 285527 | RNAseq | 0.1093 | 0.5635 | |
| SRP064894 | FRYL | 285527 | RNAseq | -0.0451 | 0.8115 | |
| SRP133303 | FRYL | 285527 | RNAseq | 0.3350 | 0.1842 | |
| SRP159526 | FRYL | 285527 | RNAseq | -0.5269 | 0.0054 | |
| SRP193095 | FRYL | 285527 | RNAseq | -0.2448 | 0.0498 | |
| SRP219564 | FRYL | 285527 | RNAseq | -0.2051 | 0.3931 | |
| TCGA | FRYL | 285527 | RNAseq | -0.0865 | 0.1159 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FRYL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FRYL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FRYL | 285527 | 1 | 15 | 14 | |
| GSE20123 | FRYL | 285527 | 1 | 15 | 14 | |
| GSE43470 | FRYL | 285527 | 0 | 14 | 29 | |
| GSE46452 | FRYL | 285527 | 1 | 37 | 21 | |
| GSE47630 | FRYL | 285527 | 1 | 18 | 21 | |
| GSE54993 | FRYL | 285527 | 7 | 0 | 63 | |
| GSE54994 | FRYL | 285527 | 4 | 9 | 40 | |
| GSE60625 | FRYL | 285527 | 0 | 0 | 11 | |
| GSE74703 | FRYL | 285527 | 0 | 12 | 24 | |
| GSE74704 | FRYL | 285527 | 0 | 9 | 11 | |
| TCGA | FRYL | 285527 | 21 | 34 | 41 |
Total number of gains: 36; Total number of losses: 163; Total Number of normals: 289.
Somatic mutations of FRYL:
Generating mutation plots.
Highly correlated genes for FRYL:
Showing top 20/159 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FRYL | TMEM65 | 0.767073 | 3 | 0 | 3 |
| FRYL | MYH3 | 0.754244 | 3 | 0 | 3 |
| FRYL | KIAA1143 | 0.732173 | 3 | 0 | 3 |
| FRYL | ERP44 | 0.727206 | 3 | 0 | 3 |
| FRYL | LIPT1 | 0.717344 | 3 | 0 | 3 |
| FRYL | RBM18 | 0.715039 | 3 | 0 | 3 |
| FRYL | ATP7A | 0.710139 | 3 | 0 | 3 |
| FRYL | PCGF3 | 0.705688 | 5 | 0 | 4 |
| FRYL | HP1BP3 | 0.693714 | 4 | 0 | 3 |
| FRYL | FPGT | 0.6931 | 3 | 0 | 3 |
| FRYL | GNPDA2 | 0.693004 | 3 | 0 | 3 |
| FRYL | KPNA6 | 0.689911 | 3 | 0 | 3 |
| FRYL | RAB27A | 0.687413 | 3 | 0 | 3 |
| FRYL | ZBTB11 | 0.68635 | 3 | 0 | 3 |
| FRYL | NFXL1 | 0.682286 | 4 | 0 | 3 |
| FRYL | NLGN4Y | 0.676274 | 3 | 0 | 3 |
| FRYL | ACSL5 | 0.664093 | 5 | 0 | 4 |
| FRYL | VMA21 | 0.658547 | 3 | 0 | 3 |
| FRYL | PRKD3 | 0.655172 | 4 | 0 | 4 |
| FRYL | OCIAD1 | 0.653493 | 4 | 0 | 3 |
For details and further investigation, click here
