| Full name: lipoyltransferase 1 | Alias Symbol: MGC12290|MGC13378 | ||
| Type: protein-coding gene | Cytoband: 2q11.2 | ||
| Entrez ID: 51601 | HGNC ID: HGNC:29569 | Ensembl Gene: ENSG00000144182 | OMIM ID: 610284 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of LIPT1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LIPT1 | 51601 | 205571_at | -0.1360 | 0.8347 | |
| GSE20347 | LIPT1 | 51601 | 205571_at | 0.1113 | 0.6228 | |
| GSE23400 | LIPT1 | 51601 | 205571_at | 0.0351 | 0.5860 | |
| GSE26886 | LIPT1 | 51601 | 205571_at | -0.1925 | 0.3916 | |
| GSE29001 | LIPT1 | 51601 | 205571_at | 0.0833 | 0.8549 | |
| GSE38129 | LIPT1 | 51601 | 205571_at | -0.0503 | 0.7565 | |
| GSE45670 | LIPT1 | 51601 | 205571_at | -0.2545 | 0.3299 | |
| GSE53622 | LIPT1 | 51601 | 7744 | -0.0372 | 0.6778 | |
| GSE53624 | LIPT1 | 51601 | 7744 | -0.0392 | 0.6420 | |
| GSE63941 | LIPT1 | 51601 | 205571_at | 0.5451 | 0.2951 | |
| GSE77861 | LIPT1 | 51601 | 205571_at | -0.0318 | 0.9231 | |
| GSE97050 | LIPT1 | 51601 | A_23_P501805 | 0.0745 | 0.7883 | |
| SRP007169 | LIPT1 | 51601 | RNAseq | -0.1579 | 0.7997 | |
| SRP064894 | LIPT1 | 51601 | RNAseq | -0.2866 | 0.1263 | |
| SRP133303 | LIPT1 | 51601 | RNAseq | -0.0687 | 0.6692 | |
| SRP159526 | LIPT1 | 51601 | RNAseq | 0.0885 | 0.7640 | |
| SRP193095 | LIPT1 | 51601 | RNAseq | -0.1012 | 0.2587 | |
| SRP219564 | LIPT1 | 51601 | RNAseq | -0.1196 | 0.7317 | |
| TCGA | LIPT1 | 51601 | RNAseq | -0.1190 | 0.1880 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LIPT1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LIPT1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LIPT1 | 51601 | 6 | 2 | 22 | |
| GSE20123 | LIPT1 | 51601 | 6 | 2 | 22 | |
| GSE43470 | LIPT1 | 51601 | 3 | 1 | 39 | |
| GSE46452 | LIPT1 | 51601 | 2 | 3 | 54 | |
| GSE47630 | LIPT1 | 51601 | 7 | 0 | 33 | |
| GSE54993 | LIPT1 | 51601 | 0 | 6 | 64 | |
| GSE54994 | LIPT1 | 51601 | 10 | 0 | 43 | |
| GSE60625 | LIPT1 | 51601 | 0 | 3 | 8 | |
| GSE74703 | LIPT1 | 51601 | 3 | 1 | 32 | |
| GSE74704 | LIPT1 | 51601 | 4 | 1 | 15 | |
| TCGA | LIPT1 | 51601 | 34 | 4 | 58 |
Total number of gains: 75; Total number of losses: 23; Total Number of normals: 390.
Somatic mutations of LIPT1:
Generating mutation plots.
Highly correlated genes for LIPT1:
Showing top 20/538 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LIPT1 | VAMP3 | 0.811161 | 3 | 0 | 3 |
| LIPT1 | CASP3 | 0.804863 | 3 | 0 | 3 |
| LIPT1 | PGBD4 | 0.789143 | 3 | 0 | 3 |
| LIPT1 | MCPH1 | 0.775652 | 3 | 0 | 3 |
| LIPT1 | DMTF1 | 0.763783 | 3 | 0 | 3 |
| LIPT1 | TTC33 | 0.760285 | 3 | 0 | 3 |
| LIPT1 | MGA | 0.754757 | 3 | 0 | 3 |
| LIPT1 | TMEM219 | 0.754184 | 3 | 0 | 3 |
| LIPT1 | MFN1 | 0.750879 | 4 | 0 | 3 |
| LIPT1 | UBR2 | 0.750094 | 3 | 0 | 3 |
| LIPT1 | RSRC2 | 0.747357 | 5 | 0 | 5 |
| LIPT1 | UBE2A | 0.745977 | 3 | 0 | 3 |
| LIPT1 | SOCS7 | 0.743612 | 3 | 0 | 3 |
| LIPT1 | FMR1 | 0.741079 | 4 | 0 | 4 |
| LIPT1 | TCTN1 | 0.73891 | 3 | 0 | 3 |
| LIPT1 | THAP9-AS1 | 0.735652 | 3 | 0 | 3 |
| LIPT1 | TERF2IP | 0.733121 | 3 | 0 | 3 |
| LIPT1 | SLITRK6 | 0.731098 | 3 | 0 | 3 |
| LIPT1 | MAPKAP1 | 0.72399 | 3 | 0 | 3 |
| LIPT1 | ASXL2 | 0.723658 | 4 | 0 | 4 |
For details and further investigation, click here
