| Full name: polycomb group ring finger 3 | Alias Symbol: FLJ36550|DONG1|RNF3A|MGC40413 | ||
| Type: protein-coding gene | Cytoband: 4p16.3 | ||
| Entrez ID: 10336 | HGNC ID: HGNC:10066 | Ensembl Gene: ENSG00000185619 | OMIM ID: 617543 |
| Drug and gene relationship at DGIdb | |||
Expression of PCGF3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PCGF3 | 10336 | 212753_at | -0.0113 | 0.9846 | |
| GSE20347 | PCGF3 | 10336 | 212753_at | -0.3222 | 0.0192 | |
| GSE23400 | PCGF3 | 10336 | 212753_at | -0.1777 | 0.0250 | |
| GSE26886 | PCGF3 | 10336 | 212753_at | -0.7321 | 0.0009 | |
| GSE29001 | PCGF3 | 10336 | 212753_at | -0.2239 | 0.3198 | |
| GSE38129 | PCGF3 | 10336 | 212753_at | -0.1429 | 0.1642 | |
| GSE45670 | PCGF3 | 10336 | 212753_at | 0.1120 | 0.4562 | |
| GSE53622 | PCGF3 | 10336 | 16696 | -0.2535 | 0.0001 | |
| GSE53624 | PCGF3 | 10336 | 16696 | -0.0732 | 0.2265 | |
| GSE63941 | PCGF3 | 10336 | 212753_at | -0.8906 | 0.0317 | |
| GSE77861 | PCGF3 | 10336 | 212753_at | -0.0455 | 0.8710 | |
| GSE97050 | PCGF3 | 10336 | A_33_P3404126 | -0.3352 | 0.3006 | |
| SRP007169 | PCGF3 | 10336 | RNAseq | -0.8565 | 0.0428 | |
| SRP008496 | PCGF3 | 10336 | RNAseq | -0.8384 | 0.0004 | |
| SRP064894 | PCGF3 | 10336 | RNAseq | 0.2119 | 0.2989 | |
| SRP133303 | PCGF3 | 10336 | RNAseq | -0.2090 | 0.0978 | |
| SRP159526 | PCGF3 | 10336 | RNAseq | -0.4031 | 0.3000 | |
| SRP193095 | PCGF3 | 10336 | RNAseq | -0.3103 | 0.0092 | |
| SRP219564 | PCGF3 | 10336 | RNAseq | 0.0040 | 0.9941 | |
| TCGA | PCGF3 | 10336 | RNAseq | -0.1162 | 0.0185 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PCGF3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PCGF3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PCGF3 | 10336 | 0 | 17 | 13 | |
| GSE20123 | PCGF3 | 10336 | 0 | 15 | 15 | |
| GSE43470 | PCGF3 | 10336 | 0 | 17 | 26 | |
| GSE46452 | PCGF3 | 10336 | 1 | 36 | 22 | |
| GSE47630 | PCGF3 | 10336 | 3 | 19 | 18 | |
| GSE54993 | PCGF3 | 10336 | 11 | 0 | 59 | |
| GSE54994 | PCGF3 | 10336 | 3 | 12 | 38 | |
| GSE60625 | PCGF3 | 10336 | 0 | 0 | 11 | |
| GSE74703 | PCGF3 | 10336 | 0 | 13 | 23 | |
| GSE74704 | PCGF3 | 10336 | 0 | 8 | 12 | |
| TCGA | PCGF3 | 10336 | 9 | 47 | 40 |
Total number of gains: 27; Total number of losses: 184; Total Number of normals: 277.
Somatic mutations of PCGF3:
Generating mutation plots.
Highly correlated genes for PCGF3:
Showing top 20/243 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PCGF3 | CPEB4 | 0.786997 | 3 | 0 | 3 |
| PCGF3 | RAB3D | 0.784213 | 3 | 0 | 3 |
| PCGF3 | SLC12A6 | 0.774457 | 3 | 0 | 3 |
| PCGF3 | SMURF1 | 0.770867 | 3 | 0 | 3 |
| PCGF3 | RNASEL | 0.749335 | 3 | 0 | 3 |
| PCGF3 | IFT80 | 0.74283 | 3 | 0 | 3 |
| PCGF3 | ZNF585A | 0.738855 | 3 | 0 | 3 |
| PCGF3 | AFAP1 | 0.737736 | 3 | 0 | 3 |
| PCGF3 | ZFP3 | 0.73667 | 3 | 0 | 3 |
| PCGF3 | PSMD5 | 0.729447 | 3 | 0 | 3 |
| PCGF3 | SLC44A3 | 0.726548 | 3 | 0 | 3 |
| PCGF3 | TRIM23 | 0.720547 | 3 | 0 | 3 |
| PCGF3 | TBC1D20 | 0.717198 | 3 | 0 | 3 |
| PCGF3 | ANKHD1 | 0.714078 | 3 | 0 | 3 |
| PCGF3 | ZCCHC8 | 0.711225 | 3 | 0 | 3 |
| PCGF3 | ZSCAN29 | 0.709017 | 3 | 0 | 3 |
| PCGF3 | EPG5 | 0.707486 | 3 | 0 | 3 |
| PCGF3 | FRYL | 0.705688 | 5 | 0 | 4 |
| PCGF3 | GRAMD1C | 0.705265 | 3 | 0 | 3 |
| PCGF3 | BECN1 | 0.701879 | 3 | 0 | 3 |
For details and further investigation, click here
