| Full name: transmembrane protein 65 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 8q24.13 | ||
| Entrez ID: 157378 | HGNC ID: HGNC:25203 | Ensembl Gene: ENSG00000164983 | OMIM ID: 616609 |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM65:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM65 | 157378 | 241342_at | 0.5497 | 0.5130 | |
| GSE26886 | TMEM65 | 157378 | 241342_at | 0.4284 | 0.0386 | |
| GSE45670 | TMEM65 | 157378 | 241342_at | 0.4870 | 0.0104 | |
| GSE53622 | TMEM65 | 157378 | 24842 | 0.2887 | 0.0058 | |
| GSE53624 | TMEM65 | 157378 | 24842 | 0.0763 | 0.4502 | |
| GSE63941 | TMEM65 | 157378 | 241342_at | -0.9359 | 0.1617 | |
| GSE77861 | TMEM65 | 157378 | 241342_at | -0.2368 | 0.5689 | |
| GSE97050 | TMEM65 | 157378 | A_33_P3494748 | 0.2348 | 0.3046 | |
| SRP007169 | TMEM65 | 157378 | RNAseq | -0.8333 | 0.0060 | |
| SRP008496 | TMEM65 | 157378 | RNAseq | -0.3577 | 0.1946 | |
| SRP064894 | TMEM65 | 157378 | RNAseq | 0.5699 | 0.0292 | |
| SRP133303 | TMEM65 | 157378 | RNAseq | 0.5125 | 0.0027 | |
| SRP159526 | TMEM65 | 157378 | RNAseq | -0.3439 | 0.2291 | |
| SRP193095 | TMEM65 | 157378 | RNAseq | -0.0447 | 0.7837 | |
| SRP219564 | TMEM65 | 157378 | RNAseq | 0.4544 | 0.2744 | |
| TCGA | TMEM65 | 157378 | RNAseq | 0.3958 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMEM65 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM65:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM65 | 157378 | 19 | 0 | 11 | |
| GSE20123 | TMEM65 | 157378 | 20 | 0 | 10 | |
| GSE43470 | TMEM65 | 157378 | 22 | 0 | 21 | |
| GSE46452 | TMEM65 | 157378 | 27 | 0 | 32 | |
| GSE47630 | TMEM65 | 157378 | 24 | 0 | 16 | |
| GSE54993 | TMEM65 | 157378 | 0 | 21 | 49 | |
| GSE54994 | TMEM65 | 157378 | 37 | 1 | 15 | |
| GSE60625 | TMEM65 | 157378 | 0 | 4 | 7 | |
| GSE74703 | TMEM65 | 157378 | 19 | 0 | 17 | |
| GSE74704 | TMEM65 | 157378 | 13 | 0 | 7 | |
| TCGA | TMEM65 | 157378 | 68 | 1 | 27 |
Total number of gains: 249; Total number of losses: 27; Total Number of normals: 212.
Somatic mutations of TMEM65:
Generating mutation plots.
Highly correlated genes for TMEM65:
Showing top 20/183 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM65 | GPATCH2 | 0.832276 | 3 | 0 | 3 |
| TMEM65 | RABEP1 | 0.805996 | 3 | 0 | 3 |
| TMEM65 | GDAP1 | 0.791237 | 3 | 0 | 3 |
| TMEM65 | TMEM167A | 0.784592 | 3 | 0 | 3 |
| TMEM65 | TM9SF1 | 0.773455 | 3 | 0 | 3 |
| TMEM65 | FRYL | 0.767073 | 3 | 0 | 3 |
| TMEM65 | C17orf75 | 0.761438 | 3 | 0 | 3 |
| TMEM65 | VAX2 | 0.76052 | 3 | 0 | 3 |
| TMEM65 | CEP97 | 0.757063 | 3 | 0 | 3 |
| TMEM65 | ASPH | 0.74629 | 3 | 0 | 3 |
| TMEM65 | ANKRD9 | 0.736327 | 3 | 0 | 3 |
| TMEM65 | PSMD12 | 0.734105 | 3 | 0 | 3 |
| TMEM65 | EXOSC8 | 0.729972 | 3 | 0 | 3 |
| TMEM65 | TYW5 | 0.72574 | 3 | 0 | 3 |
| TMEM65 | ABCB7 | 0.724608 | 3 | 0 | 3 |
| TMEM65 | SNX5 | 0.720737 | 3 | 0 | 3 |
| TMEM65 | ADAM19 | 0.716668 | 3 | 0 | 3 |
| TMEM65 | WRN | 0.713803 | 3 | 0 | 3 |
| TMEM65 | TGDS | 0.70867 | 3 | 0 | 3 |
| TMEM65 | MRPS28 | 0.70717 | 4 | 0 | 3 |
For details and further investigation, click here
