| Full name: nuclear transcription factor, X-box binding like 1 | Alias Symbol: HOZFP | ||
| Type: protein-coding gene | Cytoband: 4p12 | ||
| Entrez ID: 152518 | HGNC ID: HGNC:18726 | Ensembl Gene: ENSG00000170448 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of NFXL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NFXL1 | 152518 | 227220_at | 0.3254 | 0.3522 | |
| GSE26886 | NFXL1 | 152518 | 227220_at | -0.6633 | 0.0210 | |
| GSE45670 | NFXL1 | 152518 | 227220_at | 0.2284 | 0.2103 | |
| GSE53622 | NFXL1 | 152518 | 59810 | -0.0250 | 0.7791 | |
| GSE53624 | NFXL1 | 152518 | 59810 | 0.0369 | 0.6574 | |
| GSE63941 | NFXL1 | 152518 | 227220_at | -0.0973 | 0.8970 | |
| GSE77861 | NFXL1 | 152518 | 227220_at | -0.1310 | 0.4959 | |
| GSE97050 | NFXL1 | 152518 | A_33_P3405004 | -0.2391 | 0.3750 | |
| SRP007169 | NFXL1 | 152518 | RNAseq | 0.5888 | 0.2815 | |
| SRP008496 | NFXL1 | 152518 | RNAseq | 0.3950 | 0.2609 | |
| SRP064894 | NFXL1 | 152518 | RNAseq | 0.1867 | 0.4008 | |
| SRP133303 | NFXL1 | 152518 | RNAseq | 0.2755 | 0.0939 | |
| SRP159526 | NFXL1 | 152518 | RNAseq | -0.0546 | 0.8424 | |
| SRP193095 | NFXL1 | 152518 | RNAseq | -0.1001 | 0.3451 | |
| SRP219564 | NFXL1 | 152518 | RNAseq | 0.2886 | 0.5499 | |
| TCGA | NFXL1 | 152518 | RNAseq | 0.0701 | 0.3173 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NFXL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NFXL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NFXL1 | 152518 | 1 | 15 | 14 | |
| GSE20123 | NFXL1 | 152518 | 1 | 15 | 14 | |
| GSE43470 | NFXL1 | 152518 | 0 | 13 | 30 | |
| GSE46452 | NFXL1 | 152518 | 1 | 37 | 21 | |
| GSE47630 | NFXL1 | 152518 | 1 | 18 | 21 | |
| GSE54993 | NFXL1 | 152518 | 7 | 0 | 63 | |
| GSE54994 | NFXL1 | 152518 | 4 | 9 | 40 | |
| GSE60625 | NFXL1 | 152518 | 0 | 0 | 11 | |
| GSE74703 | NFXL1 | 152518 | 0 | 11 | 25 | |
| GSE74704 | NFXL1 | 152518 | 0 | 9 | 11 | |
| TCGA | NFXL1 | 152518 | 18 | 30 | 48 |
Total number of gains: 33; Total number of losses: 157; Total Number of normals: 298.
Somatic mutations of NFXL1:
Generating mutation plots.
Highly correlated genes for NFXL1:
Showing top 20/256 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NFXL1 | NEK4 | 0.861181 | 3 | 0 | 3 |
| NFXL1 | RBM26 | 0.827288 | 3 | 0 | 3 |
| NFXL1 | YTHDF2 | 0.821182 | 3 | 0 | 3 |
| NFXL1 | NAA25 | 0.789647 | 4 | 0 | 4 |
| NFXL1 | NCOA6 | 0.784736 | 3 | 0 | 3 |
| NFXL1 | CCDC15 | 0.77877 | 3 | 0 | 3 |
| NFXL1 | TMEM218 | 0.773709 | 3 | 0 | 3 |
| NFXL1 | TADA1 | 0.764588 | 3 | 0 | 3 |
| NFXL1 | WDR59 | 0.76164 | 3 | 0 | 3 |
| NFXL1 | MIS18A | 0.758892 | 3 | 0 | 3 |
| NFXL1 | SCOC | 0.758255 | 3 | 0 | 3 |
| NFXL1 | GGA3 | 0.757664 | 3 | 0 | 3 |
| NFXL1 | ZNF578 | 0.749765 | 3 | 0 | 3 |
| NFXL1 | ZFAND1 | 0.745125 | 3 | 0 | 3 |
| NFXL1 | KLHDC1 | 0.743236 | 3 | 0 | 3 |
| NFXL1 | MKRN2 | 0.740474 | 3 | 0 | 3 |
| NFXL1 | RBM34 | 0.740185 | 4 | 0 | 4 |
| NFXL1 | UBE2V2 | 0.738077 | 3 | 0 | 3 |
| NFXL1 | DNAJC3 | 0.737903 | 3 | 0 | 3 |
| NFXL1 | EPM2AIP1 | 0.735624 | 3 | 0 | 3 |
For details and further investigation, click here
