| Full name: gamma-aminobutyric acid type A receptor theta subunit | Alias Symbol: THETA | ||
| Type: protein-coding gene | Cytoband: Xq28 | ||
| Entrez ID: 55879 | HGNC ID: HGNC:14454 | Ensembl Gene: ENSG00000268089 | OMIM ID: 300349 |
| Drug and gene relationship at DGIdb | |||
GABRQ involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04727 | GABAergic synapse | |
| hsa05032 | Morphine addiction |
Expression of GABRQ:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GABRQ | 55879 | 238123_at | 0.1019 | 0.8291 | |
| GSE20347 | GABRQ | 55879 | 220886_at | 0.0177 | 0.8235 | |
| GSE23400 | GABRQ | 55879 | 220886_at | -0.1212 | 0.0037 | |
| GSE26886 | GABRQ | 55879 | 238123_at | 0.3000 | 0.3123 | |
| GSE29001 | GABRQ | 55879 | 220886_at | -0.2712 | 0.0256 | |
| GSE38129 | GABRQ | 55879 | 220886_at | -0.0285 | 0.6983 | |
| GSE45670 | GABRQ | 55879 | 238123_at | 0.5888 | 0.0152 | |
| GSE53622 | GABRQ | 55879 | 68910 | 0.8216 | 0.0000 | |
| GSE53624 | GABRQ | 55879 | 68910 | 0.8157 | 0.0000 | |
| GSE63941 | GABRQ | 55879 | 238123_at | 0.4108 | 0.1605 | |
| GSE77861 | GABRQ | 55879 | 238123_at | 0.0723 | 0.7252 | |
| GSE97050 | GABRQ | 55879 | A_23_P125475 | 0.2557 | 0.2574 | |
| SRP007169 | GABRQ | 55879 | RNAseq | 1.5253 | 0.0103 | |
| SRP133303 | GABRQ | 55879 | RNAseq | 2.6413 | 0.0000 | |
| SRP159526 | GABRQ | 55879 | RNAseq | 1.6860 | 0.0045 | |
| TCGA | GABRQ | 55879 | RNAseq | 3.0181 | 0.0000 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by GABRQ expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GABRQ:
No record found for this gene.
Somatic mutations of GABRQ:
Generating mutation plots.
Highly correlated genes for GABRQ:
Showing top 20/270 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GABRQ | RABEP2 | 0.693376 | 3 | 0 | 3 |
| GABRQ | AURKAIP1 | 0.690776 | 3 | 0 | 3 |
| GABRQ | FAM83F | 0.686358 | 4 | 0 | 4 |
| GABRQ | OTUD7B | 0.68096 | 3 | 0 | 3 |
| GABRQ | ZNF74 | 0.671224 | 3 | 0 | 3 |
| GABRQ | ARMC7 | 0.66884 | 3 | 0 | 3 |
| GABRQ | AMHR2 | 0.663219 | 4 | 0 | 4 |
| GABRQ | OR2H2 | 0.657401 | 4 | 0 | 4 |
| GABRQ | CAMK1G | 0.65255 | 3 | 0 | 3 |
| GABRQ | PLEKHG4B | 0.645194 | 4 | 0 | 3 |
| GABRQ | DEFA4 | 0.640428 | 4 | 0 | 4 |
| GABRQ | CDX2 | 0.639058 | 4 | 0 | 3 |
| GABRQ | GYG2 | 0.63796 | 4 | 0 | 3 |
| GABRQ | LILRA2 | 0.6369 | 3 | 0 | 3 |
| GABRQ | B9D2 | 0.63526 | 5 | 0 | 4 |
| GABRQ | SLC28A2 | 0.632136 | 4 | 0 | 3 |
| GABRQ | CCDC70 | 0.628447 | 5 | 0 | 5 |
| GABRQ | AP4S1 | 0.628265 | 4 | 0 | 4 |
| GABRQ | TACR3 | 0.627081 | 3 | 0 | 3 |
| GABRQ | HPX | 0.625079 | 5 | 0 | 4 |
For details and further investigation, click here
