| Full name: aurora kinase A interacting protein 1 | Alias Symbol: AKIP|AIP|FLJ20608 | ||
| Type: protein-coding gene | Cytoband: 1p36.33 | ||
| Entrez ID: 54998 | HGNC ID: HGNC:24114 | Ensembl Gene: ENSG00000175756 | OMIM ID: 609183 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of AURKAIP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AURKAIP1 | 54998 | 225552_x_at | 0.4008 | 0.2281 | |
| GSE20347 | AURKAIP1 | 54998 | 218580_x_at | -0.0859 | 0.5054 | |
| GSE23400 | AURKAIP1 | 54998 | 218580_x_at | 0.1317 | 0.0527 | |
| GSE26886 | AURKAIP1 | 54998 | 218580_x_at | 1.3068 | 0.0000 | |
| GSE29001 | AURKAIP1 | 54998 | 218580_x_at | -0.1946 | 0.4875 | |
| GSE38129 | AURKAIP1 | 54998 | 218580_x_at | 0.0491 | 0.6360 | |
| GSE45670 | AURKAIP1 | 54998 | 218580_x_at | 0.2400 | 0.1050 | |
| GSE53622 | AURKAIP1 | 54998 | 99914 | -0.1837 | 0.0111 | |
| GSE53624 | AURKAIP1 | 54998 | 99914 | 0.0610 | 0.2876 | |
| GSE63941 | AURKAIP1 | 54998 | 218580_x_at | 0.7205 | 0.0336 | |
| GSE77861 | AURKAIP1 | 54998 | 218580_x_at | 0.0736 | 0.7339 | |
| GSE97050 | AURKAIP1 | 54998 | A_33_P3240518 | 0.0657 | 0.8186 | |
| SRP007169 | AURKAIP1 | 54998 | RNAseq | -1.3523 | 0.0017 | |
| SRP008496 | AURKAIP1 | 54998 | RNAseq | -1.1115 | 0.0000 | |
| SRP064894 | AURKAIP1 | 54998 | RNAseq | 0.7142 | 0.0646 | |
| SRP133303 | AURKAIP1 | 54998 | RNAseq | 0.1480 | 0.3930 | |
| SRP159526 | AURKAIP1 | 54998 | RNAseq | 0.0282 | 0.9205 | |
| SRP193095 | AURKAIP1 | 54998 | RNAseq | -0.2540 | 0.0196 | |
| SRP219564 | AURKAIP1 | 54998 | RNAseq | 0.0100 | 0.9743 | |
| TCGA | AURKAIP1 | 54998 | RNAseq | -0.0159 | 0.7737 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by AURKAIP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AURKAIP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AURKAIP1 | 54998 | 3 | 7 | 20 | |
| GSE20123 | AURKAIP1 | 54998 | 3 | 6 | 21 | |
| GSE43470 | AURKAIP1 | 54998 | 3 | 5 | 35 | |
| GSE46452 | AURKAIP1 | 54998 | 7 | 1 | 51 | |
| GSE47630 | AURKAIP1 | 54998 | 8 | 4 | 28 | |
| GSE54993 | AURKAIP1 | 54998 | 2 | 2 | 66 | |
| GSE54994 | AURKAIP1 | 54998 | 15 | 2 | 36 | |
| GSE60625 | AURKAIP1 | 54998 | 0 | 0 | 11 | |
| GSE74703 | AURKAIP1 | 54998 | 3 | 3 | 30 | |
| GSE74704 | AURKAIP1 | 54998 | 3 | 0 | 17 | |
| TCGA | AURKAIP1 | 54998 | 14 | 20 | 62 |
Total number of gains: 61; Total number of losses: 50; Total Number of normals: 377.
Somatic mutations of AURKAIP1:
Generating mutation plots.
Highly correlated genes for AURKAIP1:
Showing top 20/900 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AURKAIP1 | RIOK1 | 0.842253 | 3 | 0 | 3 |
| AURKAIP1 | MORC2 | 0.820751 | 3 | 0 | 3 |
| AURKAIP1 | ZSCAN12 | 0.811988 | 3 | 0 | 3 |
| AURKAIP1 | LRRC58 | 0.808638 | 3 | 0 | 3 |
| AURKAIP1 | PLXNA1 | 0.80064 | 3 | 0 | 3 |
| AURKAIP1 | NMD3 | 0.79818 | 3 | 0 | 3 |
| AURKAIP1 | ALG1 | 0.792201 | 3 | 0 | 3 |
| AURKAIP1 | ENO2 | 0.779422 | 3 | 0 | 3 |
| AURKAIP1 | ZNF121 | 0.775746 | 3 | 0 | 3 |
| AURKAIP1 | EMILIN2 | 0.775571 | 3 | 0 | 3 |
| AURKAIP1 | SEC22A | 0.773991 | 3 | 0 | 3 |
| AURKAIP1 | DEK | 0.769157 | 3 | 0 | 3 |
| AURKAIP1 | MAP1S | 0.767846 | 3 | 0 | 3 |
| AURKAIP1 | CSTF2T | 0.765301 | 3 | 0 | 3 |
| AURKAIP1 | A1BG | 0.765168 | 3 | 0 | 3 |
| AURKAIP1 | RAD23A | 0.763098 | 4 | 0 | 3 |
| AURKAIP1 | ATR | 0.760091 | 3 | 0 | 3 |
| AURKAIP1 | ZNF319 | 0.759794 | 3 | 0 | 3 |
| AURKAIP1 | FLVCR1 | 0.759473 | 3 | 0 | 3 |
| AURKAIP1 | CENPV | 0.755848 | 3 | 0 | 3 |
For details and further investigation, click here
