| Full name: polypeptide N-acetylgalactosaminyltransferase 2 | Alias Symbol: GalNAc-T2 | ||
| Type: protein-coding gene | Cytoband: 1q42.13 | ||
| Entrez ID: 2590 | HGNC ID: HGNC:4124 | Ensembl Gene: ENSG00000143641 | OMIM ID: 602274 |
| Drug and gene relationship at DGIdb | |||
Expression of GALNT2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GALNT2 | 2590 | 217788_s_at | 1.0578 | 0.0445 | |
| GSE20347 | GALNT2 | 2590 | 217788_s_at | 0.4709 | 0.0143 | |
| GSE23400 | GALNT2 | 2590 | 217788_s_at | 0.4801 | 0.0000 | |
| GSE26886 | GALNT2 | 2590 | 217788_s_at | 0.5455 | 0.0267 | |
| GSE29001 | GALNT2 | 2590 | 217788_s_at | 0.5665 | 0.0843 | |
| GSE38129 | GALNT2 | 2590 | 217788_s_at | 0.4854 | 0.0087 | |
| GSE45670 | GALNT2 | 2590 | 217788_s_at | 0.6211 | 0.0014 | |
| GSE53622 | GALNT2 | 2590 | 1329 | 0.6654 | 0.0000 | |
| GSE53624 | GALNT2 | 2590 | 1329 | 0.7375 | 0.0000 | |
| GSE63941 | GALNT2 | 2590 | 217788_s_at | -1.5118 | 0.0196 | |
| GSE77861 | GALNT2 | 2590 | 217788_s_at | 0.6548 | 0.1328 | |
| GSE97050 | GALNT2 | 2590 | A_24_P353794 | 0.4222 | 0.2132 | |
| SRP007169 | GALNT2 | 2590 | RNAseq | 0.4354 | 0.3503 | |
| SRP008496 | GALNT2 | 2590 | RNAseq | 0.3679 | 0.2071 | |
| SRP064894 | GALNT2 | 2590 | RNAseq | 0.9025 | 0.0000 | |
| SRP133303 | GALNT2 | 2590 | RNAseq | 1.0178 | 0.0000 | |
| SRP159526 | GALNT2 | 2590 | RNAseq | 0.7603 | 0.0000 | |
| SRP193095 | GALNT2 | 2590 | RNAseq | 0.7024 | 0.0000 | |
| SRP219564 | GALNT2 | 2590 | RNAseq | 0.6579 | 0.1030 | |
| TCGA | GALNT2 | 2590 | RNAseq | 0.0905 | 0.1165 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by GALNT2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GALNT2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GALNT2 | 2590 | 11 | 0 | 19 | |
| GSE20123 | GALNT2 | 2590 | 11 | 0 | 19 | |
| GSE43470 | GALNT2 | 2590 | 8 | 1 | 34 | |
| GSE46452 | GALNT2 | 2590 | 4 | 2 | 53 | |
| GSE47630 | GALNT2 | 2590 | 15 | 0 | 25 | |
| GSE54993 | GALNT2 | 2590 | 0 | 6 | 64 | |
| GSE54994 | GALNT2 | 2590 | 17 | 0 | 36 | |
| GSE60625 | GALNT2 | 2590 | 0 | 0 | 11 | |
| GSE74703 | GALNT2 | 2590 | 8 | 1 | 27 | |
| GSE74704 | GALNT2 | 2590 | 5 | 0 | 15 | |
| TCGA | GALNT2 | 2590 | 45 | 3 | 48 |
Total number of gains: 124; Total number of losses: 13; Total Number of normals: 351.
Somatic mutations of GALNT2:
Generating mutation plots.
Highly correlated genes for GALNT2:
Showing top 20/1306 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GALNT2 | KLHL36 | 0.789427 | 3 | 0 | 3 |
| GALNT2 | ULK1 | 0.775125 | 3 | 0 | 3 |
| GALNT2 | RAB34 | 0.763997 | 3 | 0 | 3 |
| GALNT2 | TMTC4 | 0.7585 | 3 | 0 | 3 |
| GALNT2 | MRPS6 | 0.738333 | 5 | 0 | 5 |
| GALNT2 | FOXP4 | 0.738046 | 3 | 0 | 3 |
| GALNT2 | C20orf194 | 0.732425 | 3 | 0 | 3 |
| GALNT2 | SLC39A3 | 0.731131 | 4 | 0 | 4 |
| GALNT2 | CEP250 | 0.730626 | 4 | 0 | 3 |
| GALNT2 | FADS1 | 0.725898 | 3 | 0 | 3 |
| GALNT2 | LGALS8 | 0.725832 | 3 | 0 | 3 |
| GALNT2 | PDE7A | 0.723764 | 7 | 0 | 7 |
| GALNT2 | WDR81 | 0.721922 | 3 | 0 | 3 |
| GALNT2 | RBM15B | 0.719574 | 3 | 0 | 3 |
| GALNT2 | CD99L2 | 0.719418 | 4 | 0 | 3 |
| GALNT2 | SPON2 | 0.71889 | 3 | 0 | 3 |
| GALNT2 | TEX10 | 0.717397 | 3 | 0 | 3 |
| GALNT2 | FAM126A | 0.717315 | 3 | 0 | 3 |
| GALNT2 | S1PR3 | 0.716826 | 3 | 0 | 3 |
| GALNT2 | TRIM47 | 0.716408 | 5 | 0 | 5 |
For details and further investigation, click here
