| Full name: kelch like family member 36 | Alias Symbol: FLJ12543 | ||
| Type: protein-coding gene | Cytoband: 16q24.1 | ||
| Entrez ID: 79786 | HGNC ID: HGNC:17844 | Ensembl Gene: ENSG00000135686 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of KLHL36:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KLHL36 | 79786 | 227319_at | 0.4882 | 0.1949 | |
| GSE20347 | KLHL36 | 79786 | 219453_at | 0.2596 | 0.0236 | |
| GSE23400 | KLHL36 | 79786 | 219453_at | 0.1618 | 0.0009 | |
| GSE26886 | KLHL36 | 79786 | 227319_at | -0.6035 | 0.0917 | |
| GSE29001 | KLHL36 | 79786 | 219453_at | 0.1861 | 0.2895 | |
| GSE38129 | KLHL36 | 79786 | 219453_at | 0.4133 | 0.0009 | |
| GSE45670 | KLHL36 | 79786 | 227319_at | -0.0784 | 0.6430 | |
| GSE53622 | KLHL36 | 79786 | 140105 | -0.2898 | 0.0040 | |
| GSE53624 | KLHL36 | 79786 | 140105 | 0.2975 | 0.0002 | |
| GSE63941 | KLHL36 | 79786 | 227319_at | -0.0711 | 0.8956 | |
| GSE77861 | KLHL36 | 79786 | 227319_at | 0.1969 | 0.3581 | |
| GSE97050 | KLHL36 | 79786 | A_33_P3302393 | -0.3885 | 0.2144 | |
| SRP007169 | KLHL36 | 79786 | RNAseq | -0.7989 | 0.0211 | |
| SRP008496 | KLHL36 | 79786 | RNAseq | -0.6588 | 0.0073 | |
| SRP064894 | KLHL36 | 79786 | RNAseq | -0.1708 | 0.2422 | |
| SRP133303 | KLHL36 | 79786 | RNAseq | -0.0103 | 0.9488 | |
| SRP159526 | KLHL36 | 79786 | RNAseq | -0.4107 | 0.1907 | |
| SRP193095 | KLHL36 | 79786 | RNAseq | 0.1048 | 0.2253 | |
| SRP219564 | KLHL36 | 79786 | RNAseq | -0.5197 | 0.0491 | |
| TCGA | KLHL36 | 79786 | RNAseq | -0.1415 | 0.0108 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KLHL36 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KLHL36:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KLHL36 | 79786 | 4 | 5 | 21 | |
| GSE20123 | KLHL36 | 79786 | 4 | 5 | 21 | |
| GSE43470 | KLHL36 | 79786 | 2 | 10 | 31 | |
| GSE46452 | KLHL36 | 79786 | 37 | 2 | 20 | |
| GSE47630 | KLHL36 | 79786 | 11 | 9 | 20 | |
| GSE54993 | KLHL36 | 79786 | 3 | 4 | 63 | |
| GSE54994 | KLHL36 | 79786 | 8 | 10 | 35 | |
| GSE60625 | KLHL36 | 79786 | 4 | 0 | 7 | |
| GSE74703 | KLHL36 | 79786 | 2 | 7 | 27 | |
| GSE74704 | KLHL36 | 79786 | 3 | 3 | 14 | |
| TCGA | KLHL36 | 79786 | 26 | 16 | 54 |
Total number of gains: 104; Total number of losses: 71; Total Number of normals: 313.
Somatic mutations of KLHL36:
Generating mutation plots.
Highly correlated genes for KLHL36:
Showing top 20/315 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KLHL36 | UBR7 | 0.808364 | 3 | 0 | 3 |
| KLHL36 | POMGNT1 | 0.797858 | 3 | 0 | 3 |
| KLHL36 | USP22 | 0.79254 | 3 | 0 | 3 |
| KLHL36 | GALNT2 | 0.789427 | 3 | 0 | 3 |
| KLHL36 | DEDD | 0.783633 | 3 | 0 | 3 |
| KLHL36 | NOL9 | 0.782993 | 3 | 0 | 3 |
| KLHL36 | ZNF496 | 0.773706 | 3 | 0 | 3 |
| KLHL36 | BOD1 | 0.773364 | 3 | 0 | 3 |
| KLHL36 | C17orf80 | 0.77066 | 3 | 0 | 3 |
| KLHL36 | RNF220 | 0.765107 | 3 | 0 | 3 |
| KLHL36 | RLIM | 0.759798 | 3 | 0 | 3 |
| KLHL36 | IP6K1 | 0.756335 | 3 | 0 | 3 |
| KLHL36 | RNF34 | 0.754204 | 4 | 0 | 4 |
| KLHL36 | ERI3 | 0.748265 | 3 | 0 | 3 |
| KLHL36 | MRPS6 | 0.748247 | 3 | 0 | 3 |
| KLHL36 | SOCS4 | 0.741845 | 3 | 0 | 3 |
| KLHL36 | CNOT4 | 0.74127 | 3 | 0 | 3 |
| KLHL36 | VAPB | 0.736709 | 4 | 0 | 4 |
| KLHL36 | COMMD7 | 0.735828 | 3 | 0 | 3 |
| KLHL36 | TMED8 | 0.733686 | 3 | 0 | 3 |
For details and further investigation, click here
