| Full name: spondin 2 | Alias Symbol: DIL1 | ||
| Type: protein-coding gene | Cytoband: 4p16.3 | ||
| Entrez ID: 10417 | HGNC ID: HGNC:11253 | Ensembl Gene: ENSG00000159674 | OMIM ID: 605918 |
| Drug and gene relationship at DGIdb | |||
Expression of SPON2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | SPON2 | 10417 | 163505 | 1.1033 | 0.0000 | |
| GSE53624 | SPON2 | 10417 | 163505 | 1.4906 | 0.0000 | |
| GSE97050 | SPON2 | 10417 | A_23_P121533 | 1.1631 | 0.0737 | |
| SRP007169 | SPON2 | 10417 | RNAseq | 0.2267 | 0.6003 | |
| SRP008496 | SPON2 | 10417 | RNAseq | 0.8211 | 0.0204 | |
| SRP064894 | SPON2 | 10417 | RNAseq | 1.8064 | 0.0000 | |
| SRP133303 | SPON2 | 10417 | RNAseq | 1.2494 | 0.0000 | |
| SRP159526 | SPON2 | 10417 | RNAseq | 0.7965 | 0.0165 | |
| SRP193095 | SPON2 | 10417 | RNAseq | 1.4957 | 0.0000 | |
| SRP219564 | SPON2 | 10417 | RNAseq | 1.7441 | 0.0007 | |
| TCGA | SPON2 | 10417 | RNAseq | 0.3206 | 0.0021 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by SPON2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SPON2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SPON2 | 10417 | 0 | 16 | 14 | |
| GSE20123 | SPON2 | 10417 | 0 | 16 | 14 | |
| GSE43470 | SPON2 | 10417 | 0 | 17 | 26 | |
| GSE46452 | SPON2 | 10417 | 1 | 36 | 22 | |
| GSE47630 | SPON2 | 10417 | 2 | 19 | 19 | |
| GSE54993 | SPON2 | 10417 | 11 | 0 | 59 | |
| GSE54994 | SPON2 | 10417 | 3 | 12 | 38 | |
| GSE60625 | SPON2 | 10417 | 0 | 0 | 11 | |
| GSE74703 | SPON2 | 10417 | 0 | 13 | 23 | |
| GSE74704 | SPON2 | 10417 | 0 | 8 | 12 | |
| TCGA | SPON2 | 10417 | 9 | 47 | 40 |
Total number of gains: 26; Total number of losses: 184; Total Number of normals: 278.
Somatic mutations of SPON2:
Generating mutation plots.
Highly correlated genes for SPON2:
Showing top 20/523 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPON2 | FZD2 | 0.820794 | 3 | 0 | 3 |
| SPON2 | PLOD1 | 0.805833 | 3 | 0 | 3 |
| SPON2 | GPX8 | 0.800339 | 3 | 0 | 3 |
| SPON2 | IKBIP | 0.797882 | 3 | 0 | 3 |
| SPON2 | FKBP9 | 0.787375 | 3 | 0 | 3 |
| SPON2 | LOXL2 | 0.783673 | 3 | 0 | 3 |
| SPON2 | MYO5A | 0.783529 | 3 | 0 | 3 |
| SPON2 | AGRN | 0.781534 | 3 | 0 | 3 |
| SPON2 | ARPC1B | 0.780261 | 3 | 0 | 3 |
| SPON2 | SHC1 | 0.778192 | 3 | 0 | 3 |
| SPON2 | LAPTM4B | 0.777074 | 3 | 0 | 3 |
| SPON2 | PANX1 | 0.775423 | 3 | 0 | 3 |
| SPON2 | GNA12 | 0.773597 | 3 | 0 | 3 |
| SPON2 | LRP12 | 0.771801 | 3 | 0 | 3 |
| SPON2 | COL5A1 | 0.768826 | 4 | 0 | 4 |
| SPON2 | WDR54 | 0.768414 | 3 | 0 | 3 |
| SPON2 | B3GNT9 | 0.767693 | 3 | 0 | 3 |
| SPON2 | ANGPT2 | 0.765138 | 3 | 0 | 3 |
| SPON2 | LPCAT1 | 0.763477 | 3 | 0 | 3 |
| SPON2 | FJX1 | 0.762926 | 3 | 0 | 3 |
For details and further investigation, click here
