| Full name: galectin 8 | Alias Symbol: PCTA-1 | ||
| Type: protein-coding gene | Cytoband: 1q43 | ||
| Entrez ID: 3964 | HGNC ID: HGNC:6569 | Ensembl Gene: ENSG00000116977 | OMIM ID: 606099 |
| Drug and gene relationship at DGIdb | |||
Expression of LGALS8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LGALS8 | 3964 | 208933_s_at | 0.1884 | 0.6949 | |
| GSE20347 | LGALS8 | 3964 | 208936_x_at | 0.3538 | 0.0147 | |
| GSE23400 | LGALS8 | 3964 | 208936_x_at | 0.4458 | 0.0000 | |
| GSE26886 | LGALS8 | 3964 | 208934_s_at | 0.6572 | 0.0002 | |
| GSE29001 | LGALS8 | 3964 | 208934_s_at | 0.3408 | 0.2667 | |
| GSE38129 | LGALS8 | 3964 | 208936_x_at | 0.5930 | 0.0004 | |
| GSE45670 | LGALS8 | 3964 | 208933_s_at | -0.0107 | 0.9585 | |
| GSE63941 | LGALS8 | 3964 | 208934_s_at | 1.3489 | 0.0184 | |
| GSE77861 | LGALS8 | 3964 | 208936_x_at | 0.4878 | 0.0984 | |
| GSE97050 | LGALS8 | 3964 | A_23_P63026 | 0.4460 | 0.1503 | |
| SRP007169 | LGALS8 | 3964 | RNAseq | 0.0462 | 0.8724 | |
| SRP008496 | LGALS8 | 3964 | RNAseq | 0.0654 | 0.8249 | |
| SRP064894 | LGALS8 | 3964 | RNAseq | 0.2895 | 0.0762 | |
| SRP133303 | LGALS8 | 3964 | RNAseq | 0.3526 | 0.0011 | |
| SRP159526 | LGALS8 | 3964 | RNAseq | -0.0831 | 0.8093 | |
| SRP193095 | LGALS8 | 3964 | RNAseq | 0.1971 | 0.0821 | |
| SRP219564 | LGALS8 | 3964 | RNAseq | -0.0816 | 0.8123 | |
| TCGA | LGALS8 | 3964 | RNAseq | 0.2040 | 0.0001 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by LGALS8 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of LGALS8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LGALS8 | 3964 | 10 | 1 | 19 | |
| GSE20123 | LGALS8 | 3964 | 11 | 1 | 18 | |
| GSE43470 | LGALS8 | 3964 | 8 | 1 | 34 | |
| GSE46452 | LGALS8 | 3964 | 4 | 2 | 53 | |
| GSE47630 | LGALS8 | 3964 | 15 | 0 | 25 | |
| GSE54993 | LGALS8 | 3964 | 0 | 6 | 64 | |
| GSE54994 | LGALS8 | 3964 | 16 | 0 | 37 | |
| GSE60625 | LGALS8 | 3964 | 0 | 0 | 11 | |
| GSE74703 | LGALS8 | 3964 | 8 | 1 | 27 | |
| GSE74704 | LGALS8 | 3964 | 5 | 0 | 15 | |
| TCGA | LGALS8 | 3964 | 43 | 4 | 49 |
Total number of gains: 120; Total number of losses: 16; Total Number of normals: 352.
Somatic mutations of LGALS8:
Generating mutation plots.
Highly correlated genes for LGALS8:
Showing top 20/957 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LGALS8 | FAM32A | 0.852693 | 3 | 0 | 3 |
| LGALS8 | RHBDD2 | 0.833549 | 3 | 0 | 3 |
| LGALS8 | CCM2 | 0.825091 | 3 | 0 | 3 |
| LGALS8 | WDR54 | 0.811279 | 3 | 0 | 3 |
| LGALS8 | TMED8 | 0.808864 | 3 | 0 | 3 |
| LGALS8 | TP53I13 | 0.798207 | 3 | 0 | 3 |
| LGALS8 | SEMA3C | 0.79469 | 3 | 0 | 3 |
| LGALS8 | SSBP4 | 0.792137 | 3 | 0 | 3 |
| LGALS8 | HEATR6 | 0.786134 | 3 | 0 | 3 |
| LGALS8 | ZBED1 | 0.785747 | 3 | 0 | 3 |
| LGALS8 | TIGD1 | 0.782683 | 3 | 0 | 3 |
| LGALS8 | SLC45A4 | 0.779991 | 3 | 0 | 3 |
| LGALS8 | KRTCAP2 | 0.779834 | 3 | 0 | 3 |
| LGALS8 | ZNF317 | 0.778481 | 3 | 0 | 3 |
| LGALS8 | PPP2R3C | 0.770794 | 3 | 0 | 3 |
| LGALS8 | RBM33 | 0.768685 | 3 | 0 | 3 |
| LGALS8 | CXCL16 | 0.762566 | 3 | 0 | 3 |
| LGALS8 | CCDC24 | 0.761091 | 3 | 0 | 3 |
| LGALS8 | PRDM15 | 0.760263 | 3 | 0 | 3 |
| LGALS8 | NOL7 | 0.756796 | 3 | 0 | 3 |
For details and further investigation, click here
