| Full name: GRIP and coiled-coil domain containing 1 | Alias Symbol: FLJ22035|GCC88|GCC1P|MGC20706 | ||
| Type: protein-coding gene | Cytoband: 7q32.1 | ||
| Entrez ID: 79571 | HGNC ID: HGNC:19095 | Ensembl Gene: ENSG00000179562 | OMIM ID: 607418 |
| Drug and gene relationship at DGIdb | |||
Expression of GCC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GCC1 | 79571 | 218912_at | 0.1485 | 0.7793 | |
| GSE20347 | GCC1 | 79571 | 218912_at | 0.2566 | 0.0041 | |
| GSE23400 | GCC1 | 79571 | 218912_at | -0.0078 | 0.8607 | |
| GSE26886 | GCC1 | 79571 | 218912_at | -0.3099 | 0.1714 | |
| GSE29001 | GCC1 | 79571 | 218912_at | 0.0669 | 0.7115 | |
| GSE38129 | GCC1 | 79571 | 218912_at | 0.2430 | 0.0014 | |
| GSE45670 | GCC1 | 79571 | 218912_at | 0.3816 | 0.0006 | |
| GSE53622 | GCC1 | 79571 | 48927 | 0.0256 | 0.8217 | |
| GSE53624 | GCC1 | 79571 | 48927 | 0.1906 | 0.0379 | |
| GSE63941 | GCC1 | 79571 | 218912_at | -0.6900 | 0.0541 | |
| GSE77861 | GCC1 | 79571 | 218912_at | 0.2541 | 0.2715 | |
| GSE97050 | GCC1 | 79571 | A_23_P71094 | 0.2744 | 0.3940 | |
| SRP007169 | GCC1 | 79571 | RNAseq | 0.4542 | 0.2361 | |
| SRP008496 | GCC1 | 79571 | RNAseq | 0.3553 | 0.1844 | |
| SRP064894 | GCC1 | 79571 | RNAseq | 0.1854 | 0.1401 | |
| SRP133303 | GCC1 | 79571 | RNAseq | 0.3777 | 0.0271 | |
| SRP159526 | GCC1 | 79571 | RNAseq | -0.0425 | 0.8582 | |
| SRP193095 | GCC1 | 79571 | RNAseq | -0.0261 | 0.7788 | |
| SRP219564 | GCC1 | 79571 | RNAseq | -0.1062 | 0.7109 | |
| TCGA | GCC1 | 79571 | RNAseq | -0.0790 | 0.1280 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GCC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GCC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GCC1 | 79571 | 7 | 1 | 22 | |
| GSE20123 | GCC1 | 79571 | 7 | 2 | 21 | |
| GSE43470 | GCC1 | 79571 | 2 | 3 | 38 | |
| GSE46452 | GCC1 | 79571 | 7 | 2 | 50 | |
| GSE47630 | GCC1 | 79571 | 7 | 4 | 29 | |
| GSE54993 | GCC1 | 79571 | 3 | 5 | 62 | |
| GSE54994 | GCC1 | 79571 | 9 | 7 | 37 | |
| GSE60625 | GCC1 | 79571 | 0 | 0 | 11 | |
| GSE74703 | GCC1 | 79571 | 2 | 3 | 31 | |
| GSE74704 | GCC1 | 79571 | 3 | 2 | 15 | |
| TCGA | GCC1 | 79571 | 27 | 22 | 47 |
Total number of gains: 74; Total number of losses: 51; Total Number of normals: 363.
Somatic mutations of GCC1:
Generating mutation plots.
Highly correlated genes for GCC1:
Showing top 20/536 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GCC1 | ZNF564 | 0.791435 | 3 | 0 | 3 |
| GCC1 | EAPP | 0.774364 | 3 | 0 | 3 |
| GCC1 | MPHOSPH9 | 0.772104 | 3 | 0 | 3 |
| GCC1 | SRSF6 | 0.77129 | 3 | 0 | 3 |
| GCC1 | DNASE2 | 0.763155 | 4 | 0 | 4 |
| GCC1 | KANSL2 | 0.76296 | 3 | 0 | 3 |
| GCC1 | NUDT19 | 0.757705 | 3 | 0 | 3 |
| GCC1 | ZNF776 | 0.731106 | 3 | 0 | 3 |
| GCC1 | FBXO33 | 0.720902 | 4 | 0 | 4 |
| GCC1 | KTI12 | 0.720805 | 3 | 0 | 3 |
| GCC1 | TDG | 0.716872 | 3 | 0 | 3 |
| GCC1 | C1orf43 | 0.715095 | 3 | 0 | 3 |
| GCC1 | CNOT10 | 0.712517 | 4 | 0 | 3 |
| GCC1 | FBXW9 | 0.711928 | 4 | 0 | 4 |
| GCC1 | CHCHD6 | 0.710304 | 5 | 0 | 5 |
| GCC1 | ZNF879 | 0.710272 | 3 | 0 | 3 |
| GCC1 | BROX | 0.708161 | 3 | 0 | 3 |
| GCC1 | ARL6 | 0.707464 | 4 | 0 | 3 |
| GCC1 | CSTF2T | 0.702231 | 4 | 0 | 3 |
| GCC1 | CHAMP1 | 0.701982 | 3 | 0 | 3 |
For details and further investigation, click here
