KANSL2

 

Full name: KAT8 regulatory NSL complex subunit 2 Alias Symbol: FLJ20436|NSL2
Type: protein-coding gene Cytoband: 12q13.11
Entrez ID: 54934 HGNC ID: HGNC:26024 Ensembl Gene: ENSG00000139620 OMIM ID: 615488
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of KANSL2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 KANSL2 54934 221821_s_at -0.0222 0.9605
GSE20347 KANSL2 54934 221821_s_at 0.3802 0.0018
GSE23400 KANSL2 54934 221821_s_at 0.2611 0.0000
GSE26886 KANSL2 54934 221821_s_at 0.2461 0.1117
GSE29001 KANSL2 54934 221821_s_at 0.2041 0.5304
GSE38129 KANSL2 54934 221821_s_at 0.4037 0.0002
GSE45670 KANSL2 54934 221821_s_at 0.0837 0.4822
GSE53622 KANSL2 54934 99608 0.1428 0.0192
GSE53624 KANSL2 54934 99608 0.2605 0.0000
GSE63941 KANSL2 54934 221821_s_at 0.4379 0.1198
GSE77861 KANSL2 54934 221821_s_at 0.2113 0.2644
GSE97050 KANSL2 54934 A_24_P67929 0.1107 0.6308
SRP007169 KANSL2 54934 RNAseq -0.5716 0.1964
SRP008496 KANSL2 54934 RNAseq -0.2922 0.2610
SRP064894 KANSL2 54934 RNAseq 0.0378 0.8072
SRP133303 KANSL2 54934 RNAseq 0.3511 0.0557
SRP159526 KANSL2 54934 RNAseq 0.1947 0.4206
SRP193095 KANSL2 54934 RNAseq 0.0988 0.2925
SRP219564 KANSL2 54934 RNAseq 0.0151 0.9578

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by KANSL2 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  


Copy number change of KANSL2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 KANSL2 54934 5 1 24
GSE20123 KANSL2 54934 5 1 24
GSE43470 KANSL2 54934 3 1 39
GSE46452 KANSL2 54934 8 1 50
GSE47630 KANSL2 54934 11 2 27
GSE54993 KANSL2 54934 0 5 65
GSE54994 KANSL2 54934 6 1 46
GSE60625 KANSL2 54934 0 0 11
GSE74703 KANSL2 54934 3 1 32
GSE74704 KANSL2 54934 3 1 16
TCGA KANSL2 54934 16 12 68

Total number of gains: 60; Total number of losses: 26; Total Number of normals: 402.  


 

Somatic mutations of KANSL2:

 

Generating mutation plots.

 

Highly correlated genes for KANSL2:

 

Showing top 20/578 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
KANSL2GPATCH10.785819303
KANSL2EXOC60.785553303
KANSL2MED260.784799303
KANSL2SNRPD30.770828303
KANSL2WTAP0.767855505
KANSL2GCC10.76296303
KANSL2RPS6KA30.752877303
KANSL2RBM330.751699303
KANSL2ATG140.744503404
KANSL2ZNF7760.744499303
KANSL2HCCS0.74112404
KANSL2KIAA11430.740778303
KANSL2PPP6R30.73409303
KANSL2ZBTB440.72594303
KANSL2MRPL10.724736303
KANSL2UBE2L30.723627303
KANSL2SMARCE10.723275403
KANSL2FRS20.719988303
KANSL2DDX550.719321303
KANSL2MFAP10.717433404

For details and further investigation, click here