| Full name: E2F associated phosphoprotein | Alias Symbol: BM036|FLJ20578 | ||
| Type: protein-coding gene | Cytoband: 14q13.1 | ||
| Entrez ID: 55837 | HGNC ID: HGNC:19312 | Ensembl Gene: ENSG00000129518 | OMIM ID: 609486 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of EAPP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EAPP | 55837 | 202623_at | 0.2051 | 0.8706 | |
| GSE20347 | EAPP | 55837 | 202623_at | 0.1990 | 0.4599 | |
| GSE23400 | EAPP | 55837 | 202623_at | 0.2908 | 0.0003 | |
| GSE26886 | EAPP | 55837 | 202623_at | -0.1698 | 0.6727 | |
| GSE29001 | EAPP | 55837 | 202623_at | 0.0435 | 0.9303 | |
| GSE38129 | EAPP | 55837 | 202623_at | 0.1489 | 0.4020 | |
| GSE45670 | EAPP | 55837 | 202623_at | -0.1198 | 0.3184 | |
| GSE53622 | EAPP | 55837 | 13111 | -0.0562 | 0.5792 | |
| GSE53624 | EAPP | 55837 | 13111 | 0.0330 | 0.7106 | |
| GSE63941 | EAPP | 55837 | 202623_at | 0.3694 | 0.5887 | |
| GSE77861 | EAPP | 55837 | 202623_at | 0.2203 | 0.6076 | |
| GSE97050 | EAPP | 55837 | A_23_P128783 | 0.1337 | 0.5830 | |
| SRP007169 | EAPP | 55837 | RNAseq | -0.2455 | 0.5643 | |
| SRP008496 | EAPP | 55837 | RNAseq | -0.4148 | 0.1542 | |
| SRP064894 | EAPP | 55837 | RNAseq | -0.1135 | 0.4690 | |
| SRP133303 | EAPP | 55837 | RNAseq | 0.3048 | 0.0672 | |
| SRP159526 | EAPP | 55837 | RNAseq | 0.0395 | 0.8508 | |
| SRP193095 | EAPP | 55837 | RNAseq | -0.2052 | 0.1136 | |
| SRP219564 | EAPP | 55837 | RNAseq | 0.3287 | 0.2856 | |
| TCGA | EAPP | 55837 | RNAseq | 0.0672 | 0.2436 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by EAPP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EAPP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EAPP | 55837 | 10 | 4 | 16 | |
| GSE20123 | EAPP | 55837 | 11 | 4 | 15 | |
| GSE43470 | EAPP | 55837 | 9 | 2 | 32 | |
| GSE46452 | EAPP | 55837 | 18 | 2 | 39 | |
| GSE47630 | EAPP | 55837 | 11 | 10 | 19 | |
| GSE54993 | EAPP | 55837 | 3 | 10 | 57 | |
| GSE54994 | EAPP | 55837 | 19 | 5 | 29 | |
| GSE60625 | EAPP | 55837 | 0 | 2 | 9 | |
| GSE74703 | EAPP | 55837 | 8 | 2 | 26 | |
| GSE74704 | EAPP | 55837 | 5 | 3 | 12 | |
| TCGA | EAPP | 55837 | 32 | 14 | 50 |
Total number of gains: 126; Total number of losses: 58; Total Number of normals: 304.
Somatic mutations of EAPP:
Generating mutation plots.
Highly correlated genes for EAPP:
Showing top 20/362 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EAPP | GCC1 | 0.774364 | 3 | 0 | 3 |
| EAPP | RPP30 | 0.736348 | 3 | 0 | 3 |
| EAPP | TMCO1 | 0.716887 | 3 | 0 | 3 |
| EAPP | FRMD6 | 0.712125 | 4 | 0 | 4 |
| EAPP | BARD1 | 0.710966 | 3 | 0 | 3 |
| EAPP | NBAS | 0.703037 | 3 | 0 | 3 |
| EAPP | MRPL23 | 0.695639 | 4 | 0 | 3 |
| EAPP | SNX6 | 0.695244 | 10 | 0 | 9 |
| EAPP | UBTD2 | 0.686797 | 3 | 0 | 3 |
| EAPP | UPK1B | 0.681689 | 3 | 0 | 3 |
| EAPP | BROX | 0.680632 | 3 | 0 | 3 |
| EAPP | CLIC1 | 0.678338 | 3 | 0 | 3 |
| EAPP | NAA30 | 0.674625 | 6 | 0 | 5 |
| EAPP | ISY1 | 0.673541 | 3 | 0 | 3 |
| EAPP | DDX1 | 0.670175 | 3 | 0 | 3 |
| EAPP | DTD2 | 0.669984 | 3 | 0 | 3 |
| EAPP | PEX2 | 0.669314 | 4 | 0 | 3 |
| EAPP | NDUFA13 | 0.665761 | 4 | 0 | 4 |
| EAPP | USP37 | 0.661822 | 3 | 0 | 3 |
| EAPP | MTX2 | 0.657082 | 5 | 0 | 4 |
For details and further investigation, click here
