| Full name: chromosome 1 open reading frame 43 | Alias Symbol: NICE-3|DKFZp586G1722 | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 25912 | HGNC ID: HGNC:29876 | Ensembl Gene: ENSG00000143612 | OMIM ID: 617428 |
| Drug and gene relationship at DGIdb | |||
Expression of C1orf43:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C1orf43 | 25912 | 223034_s_at | 0.1955 | 0.2812 | |
| GSE26886 | C1orf43 | 25912 | 223034_s_at | -0.0458 | 0.8506 | |
| GSE45670 | C1orf43 | 25912 | 223034_s_at | 0.2085 | 0.0079 | |
| GSE53622 | C1orf43 | 25912 | 95146 | 0.4208 | 0.0000 | |
| GSE53624 | C1orf43 | 25912 | 95146 | 0.3889 | 0.0000 | |
| GSE63941 | C1orf43 | 25912 | 223034_s_at | 0.7230 | 0.0317 | |
| GSE77861 | C1orf43 | 25912 | 223034_s_at | 0.4331 | 0.0315 | |
| GSE97050 | C1orf43 | 25912 | A_24_P393461 | 0.3420 | 0.2576 | |
| SRP007169 | C1orf43 | 25912 | RNAseq | -0.6770 | 0.0547 | |
| SRP008496 | C1orf43 | 25912 | RNAseq | -0.3493 | 0.1063 | |
| SRP064894 | C1orf43 | 25912 | RNAseq | 0.1547 | 0.3348 | |
| SRP133303 | C1orf43 | 25912 | RNAseq | 0.2930 | 0.0240 | |
| SRP159526 | C1orf43 | 25912 | RNAseq | 0.4140 | 0.0442 | |
| SRP193095 | C1orf43 | 25912 | RNAseq | -0.1079 | 0.3480 | |
| SRP219564 | C1orf43 | 25912 | RNAseq | 0.1593 | 0.5619 | |
| TCGA | C1orf43 | 25912 | RNAseq | -0.0012 | 0.9777 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by C1orf43 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C1orf43:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C1orf43 | 25912 | 14 | 0 | 16 | |
| GSE20123 | C1orf43 | 25912 | 14 | 0 | 16 | |
| GSE43470 | C1orf43 | 25912 | 7 | 2 | 34 | |
| GSE46452 | C1orf43 | 25912 | 2 | 1 | 56 | |
| GSE47630 | C1orf43 | 25912 | 14 | 0 | 26 | |
| GSE54993 | C1orf43 | 25912 | 0 | 4 | 66 | |
| GSE54994 | C1orf43 | 25912 | 16 | 0 | 37 | |
| GSE60625 | C1orf43 | 25912 | 0 | 0 | 11 | |
| GSE74703 | C1orf43 | 25912 | 6 | 1 | 29 | |
| GSE74704 | C1orf43 | 25912 | 7 | 0 | 13 | |
| TCGA | C1orf43 | 25912 | 38 | 2 | 56 |
Total number of gains: 118; Total number of losses: 10; Total Number of normals: 360.
Somatic mutations of C1orf43:
Generating mutation plots.
Highly correlated genes for C1orf43:
Showing top 20/1247 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C1orf43 | HEXA | 0.79477 | 3 | 0 | 3 |
| C1orf43 | ZBED1 | 0.789943 | 3 | 0 | 3 |
| C1orf43 | GPR107 | 0.78297 | 3 | 0 | 3 |
| C1orf43 | NOL9 | 0.773999 | 3 | 0 | 3 |
| C1orf43 | TMED4 | 0.761415 | 3 | 0 | 3 |
| C1orf43 | SLC39A3 | 0.75751 | 3 | 0 | 3 |
| C1orf43 | GDI1 | 0.756744 | 3 | 0 | 3 |
| C1orf43 | ZHX2 | 0.751335 | 3 | 0 | 3 |
| C1orf43 | PSMC1 | 0.743174 | 3 | 0 | 3 |
| C1orf43 | OGDH | 0.738352 | 3 | 0 | 3 |
| C1orf43 | STRADA | 0.737081 | 3 | 0 | 3 |
| C1orf43 | TRRAP | 0.735389 | 4 | 0 | 4 |
| C1orf43 | DNMT1 | 0.732057 | 5 | 0 | 5 |
| C1orf43 | CCDC127 | 0.72989 | 3 | 0 | 3 |
| C1orf43 | PSMD4 | 0.72117 | 6 | 0 | 5 |
| C1orf43 | CELSR2 | 0.721111 | 3 | 0 | 3 |
| C1orf43 | KHNYN | 0.72049 | 4 | 0 | 4 |
| C1orf43 | CBLB | 0.718773 | 4 | 0 | 4 |
| C1orf43 | GCC1 | 0.715095 | 3 | 0 | 3 |
| C1orf43 | ILF2 | 0.713872 | 9 | 0 | 9 |
For details and further investigation, click here
