CHAMP1

 

Full name: chromosome alignment maintaining phosphoprotein 1 Alias Symbol: CAMP|CHAMP
Type: protein-coding gene Cytoband: 13q34
Entrez ID: 283489 HGNC ID: HGNC:20311 Ensembl Gene: ENSG00000198824 OMIM ID: 616327
Drug and gene relationship at DGIdb

 

Expression of CHAMP1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CHAMP1 283489 226194_at 0.3776 0.2223
GSE26886 CHAMP1 283489 226194_at 0.3172 0.1508
GSE45670 CHAMP1 283489 226194_at 0.1032 0.6169
GSE53622 CHAMP1 283489 73838 0.4784 0.0000
GSE53624 CHAMP1 283489 73838 0.4735 0.0000
GSE63941 CHAMP1 283489 226194_at -0.0498 0.9330
GSE77861 CHAMP1 283489 226194_at 0.1127 0.7805
GSE97050 CHAMP1 283489 A_23_P164559 0.4832 0.1983
SRP007169 CHAMP1 283489 RNAseq 0.7831 0.0561
SRP008496 CHAMP1 283489 RNAseq 1.0222 0.0005
SRP064894 CHAMP1 283489 RNAseq 0.0188 0.9458
SRP133303 CHAMP1 283489 RNAseq 0.1799 0.0919
SRP159526 CHAMP1 283489 RNAseq 0.3049 0.2770
SRP193095 CHAMP1 283489 RNAseq 0.3895 0.0035
SRP219564 CHAMP1 283489 RNAseq 0.4134 0.3855

Upregulated datasets: 1; Downregulated datasets: 0.  


 

Survival by CHAMP1 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  


Copy number change of CHAMP1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CHAMP1 283489 6 12 12
GSE20123 CHAMP1 283489 6 11 13
GSE43470 CHAMP1 283489 4 13 26
GSE46452 CHAMP1 283489 3 31 25
GSE47630 CHAMP1 283489 3 26 11
GSE54993 CHAMP1 283489 12 3 55
GSE54994 CHAMP1 283489 9 10 34
GSE60625 CHAMP1 283489 0 3 8
GSE74703 CHAMP1 283489 3 10 23
GSE74704 CHAMP1 283489 4 9 7
TCGA CHAMP1 283489 19 32 45

Total number of gains: 69; Total number of losses: 160; Total Number of normals: 259.  


 

Somatic mutations of CHAMP1:

 

Generating mutation plots.

 

Highly correlated genes for CHAMP1:

 

Showing top 20/655 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CHAMP1PHF60.800303303
CHAMP1SEC22C0.78775303
CHAMP1YARS20.779785303
CHAMP1RBBP50.775942303
CHAMP1ARID1A0.757984303
CHAMP1MFSD30.745168303
CHAMP1ATG4C0.741885303
CHAMP1PACS10.740235303
CHAMP1SMARCAD10.736826303
CHAMP1NIPA20.729244303
CHAMP1GTF3C40.725933303
CHAMP1MCMBP0.725645303
CHAMP1CDIPT0.725346303
CHAMP1TRIM280.724985303
CHAMP1PRPS20.721744303
CHAMP1GAS60.720727303
CHAMP1TOR1A0.716869303
CHAMP1ELF20.716183303
CHAMP1UROS0.716142303
CHAMP1SPNS10.714598303

For details and further investigation, click here