| Full name: GDP dissociation inhibitor 2 | Alias Symbol: RABGDIB | ||
| Type: protein-coding gene | Cytoband: 10p15.1 | ||
| Entrez ID: 2665 | HGNC ID: HGNC:4227 | Ensembl Gene: ENSG00000057608 | OMIM ID: 600767 |
| Drug and gene relationship at DGIdb | |||
Expression of GDI2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GDI2 | 2665 | 200009_at | -0.1803 | 0.5070 | |
| GSE20347 | GDI2 | 2665 | 200009_at | -0.2301 | 0.0677 | |
| GSE23400 | GDI2 | 2665 | 200009_at | -0.0192 | 0.7903 | |
| GSE26886 | GDI2 | 2665 | 200009_at | -0.3934 | 0.0087 | |
| GSE29001 | GDI2 | 2665 | 200009_at | -0.5017 | 0.1410 | |
| GSE38129 | GDI2 | 2665 | 200009_at | -0.1020 | 0.3368 | |
| GSE45670 | GDI2 | 2665 | 200009_at | -0.1739 | 0.0541 | |
| GSE53622 | GDI2 | 2665 | 57971 | -0.1587 | 0.0014 | |
| GSE53624 | GDI2 | 2665 | 57971 | -0.0858 | 0.1369 | |
| GSE63941 | GDI2 | 2665 | 200009_at | 0.1625 | 0.6535 | |
| GSE77861 | GDI2 | 2665 | 200009_at | -0.3649 | 0.1119 | |
| GSE97050 | GDI2 | 2665 | A_23_P161446 | 0.4355 | 0.2349 | |
| SRP007169 | GDI2 | 2665 | RNAseq | -0.7266 | 0.0598 | |
| SRP008496 | GDI2 | 2665 | RNAseq | -0.6718 | 0.0013 | |
| SRP064894 | GDI2 | 2665 | RNAseq | -0.3439 | 0.0056 | |
| SRP133303 | GDI2 | 2665 | RNAseq | -0.2929 | 0.0208 | |
| SRP159526 | GDI2 | 2665 | RNAseq | -0.6321 | 0.0597 | |
| SRP193095 | GDI2 | 2665 | RNAseq | -0.7424 | 0.0000 | |
| SRP219564 | GDI2 | 2665 | RNAseq | -0.6365 | 0.0874 | |
| TCGA | GDI2 | 2665 | RNAseq | 0.0345 | 0.4160 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GDI2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GDI2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GDI2 | 2665 | 6 | 7 | 17 | |
| GSE20123 | GDI2 | 2665 | 6 | 6 | 18 | |
| GSE43470 | GDI2 | 2665 | 4 | 6 | 33 | |
| GSE46452 | GDI2 | 2665 | 2 | 14 | 43 | |
| GSE47630 | GDI2 | 2665 | 6 | 14 | 20 | |
| GSE54993 | GDI2 | 2665 | 11 | 0 | 59 | |
| GSE54994 | GDI2 | 2665 | 4 | 10 | 39 | |
| GSE60625 | GDI2 | 2665 | 0 | 0 | 11 | |
| GSE74703 | GDI2 | 2665 | 3 | 4 | 29 | |
| GSE74704 | GDI2 | 2665 | 1 | 5 | 14 | |
| TCGA | GDI2 | 2665 | 20 | 24 | 52 |
Total number of gains: 63; Total number of losses: 90; Total Number of normals: 335.
Somatic mutations of GDI2:
Generating mutation plots.
Highly correlated genes for GDI2:
Showing top 20/254 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GDI2 | TMEM254 | 0.666463 | 7 | 0 | 6 |
| GDI2 | LAPTM4A | 0.659344 | 4 | 0 | 3 |
| GDI2 | BRK1 | 0.658424 | 5 | 0 | 4 |
| GDI2 | RPL41 | 0.65401 | 4 | 0 | 3 |
| GDI2 | PPP2R5E | 0.64861 | 3 | 0 | 3 |
| GDI2 | SEC13 | 0.648057 | 6 | 0 | 6 |
| GDI2 | NDUFA13 | 0.647641 | 4 | 0 | 3 |
| GDI2 | RPS15A | 0.642019 | 3 | 0 | 3 |
| GDI2 | CSNK1G1 | 0.641745 | 3 | 0 | 3 |
| GDI2 | UGP2 | 0.641143 | 5 | 0 | 5 |
| GDI2 | YME1L1 | 0.638367 | 7 | 0 | 6 |
| GDI2 | OSTC | 0.637979 | 4 | 0 | 3 |
| GDI2 | SOWAHC | 0.63469 | 3 | 0 | 3 |
| GDI2 | CYP4F22 | 0.625192 | 3 | 0 | 3 |
| GDI2 | ATP6V1C2 | 0.621196 | 4 | 0 | 3 |
| GDI2 | FOXN4 | 0.619823 | 3 | 0 | 3 |
| GDI2 | ARCN1 | 0.617066 | 4 | 0 | 3 |
| GDI2 | MRPS11 | 0.616944 | 4 | 0 | 3 |
| GDI2 | PRDX2 | 0.615719 | 3 | 0 | 3 |
| GDI2 | NTAN1 | 0.610779 | 3 | 0 | 3 |
For details and further investigation, click here
