| Full name: YME1 like 1 ATPase | Alias Symbol: YME1L | ||
| Type: protein-coding gene | Cytoband: 10p12.1 | ||
| Entrez ID: 10730 | HGNC ID: HGNC:12843 | Ensembl Gene: ENSG00000136758 | OMIM ID: 607472 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of YME1L1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | YME1L1 | 10730 | 201352_at | -0.3708 | 0.2859 | |
| GSE20347 | YME1L1 | 10730 | 201352_at | -0.3818 | 0.0057 | |
| GSE23400 | YME1L1 | 10730 | 216304_x_at | -0.0364 | 0.5857 | |
| GSE26886 | YME1L1 | 10730 | 201352_at | -0.2355 | 0.1019 | |
| GSE29001 | YME1L1 | 10730 | 201352_at | -0.1148 | 0.5244 | |
| GSE38129 | YME1L1 | 10730 | 201352_at | -0.2914 | 0.0025 | |
| GSE45670 | YME1L1 | 10730 | 201352_at | -0.1662 | 0.0901 | |
| GSE53622 | YME1L1 | 10730 | 117756 | -0.2997 | 0.0000 | |
| GSE53624 | YME1L1 | 10730 | 117756 | -0.1415 | 0.0602 | |
| GSE63941 | YME1L1 | 10730 | 201352_at | -0.1209 | 0.8102 | |
| GSE77861 | YME1L1 | 10730 | 201352_at | -0.4658 | 0.0183 | |
| GSE97050 | YME1L1 | 10730 | A_23_P104201 | -0.2743 | 0.3576 | |
| SRP007169 | YME1L1 | 10730 | RNAseq | -1.1196 | 0.0012 | |
| SRP008496 | YME1L1 | 10730 | RNAseq | -1.0634 | 0.0000 | |
| SRP064894 | YME1L1 | 10730 | RNAseq | -0.3341 | 0.0477 | |
| SRP133303 | YME1L1 | 10730 | RNAseq | -0.1338 | 0.3507 | |
| SRP159526 | YME1L1 | 10730 | RNAseq | -0.6075 | 0.0373 | |
| SRP193095 | YME1L1 | 10730 | RNAseq | -0.5081 | 0.0000 | |
| SRP219564 | YME1L1 | 10730 | RNAseq | -0.5860 | 0.1122 | |
| TCGA | YME1L1 | 10730 | RNAseq | 0.0015 | 0.9713 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by YME1L1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of YME1L1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | YME1L1 | 10730 | 5 | 7 | 18 | |
| GSE20123 | YME1L1 | 10730 | 5 | 6 | 19 | |
| GSE43470 | YME1L1 | 10730 | 3 | 4 | 36 | |
| GSE46452 | YME1L1 | 10730 | 1 | 14 | 44 | |
| GSE47630 | YME1L1 | 10730 | 5 | 15 | 20 | |
| GSE54993 | YME1L1 | 10730 | 9 | 0 | 61 | |
| GSE54994 | YME1L1 | 10730 | 3 | 9 | 41 | |
| GSE60625 | YME1L1 | 10730 | 0 | 0 | 11 | |
| GSE74703 | YME1L1 | 10730 | 2 | 2 | 32 | |
| GSE74704 | YME1L1 | 10730 | 0 | 5 | 15 | |
| TCGA | YME1L1 | 10730 | 18 | 24 | 54 |
Total number of gains: 51; Total number of losses: 86; Total Number of normals: 351.
Somatic mutations of YME1L1:
Generating mutation plots.
Highly correlated genes for YME1L1:
Showing top 20/668 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| YME1L1 | MTPN | 0.794825 | 3 | 0 | 3 |
| YME1L1 | LRRC40 | 0.792441 | 3 | 0 | 3 |
| YME1L1 | THUMPD3 | 0.757747 | 3 | 0 | 3 |
| YME1L1 | SATB1 | 0.726625 | 3 | 0 | 3 |
| YME1L1 | RAB1A | 0.718795 | 4 | 0 | 4 |
| YME1L1 | KDM3A | 0.717819 | 3 | 0 | 3 |
| YME1L1 | RSL24D1 | 0.705775 | 3 | 0 | 3 |
| YME1L1 | SLC46A2 | 0.705376 | 4 | 0 | 4 |
| YME1L1 | PPFIBP1 | 0.696912 | 3 | 0 | 3 |
| YME1L1 | COPS2 | 0.696537 | 3 | 0 | 3 |
| YME1L1 | MAP4K3 | 0.696264 | 3 | 0 | 3 |
| YME1L1 | RBX1 | 0.691385 | 4 | 0 | 3 |
| YME1L1 | RAB18 | 0.686177 | 7 | 0 | 7 |
| YME1L1 | THAP2 | 0.683662 | 4 | 0 | 3 |
| YME1L1 | MAML2 | 0.683638 | 3 | 0 | 3 |
| YME1L1 | ZRANB1 | 0.680515 | 3 | 0 | 3 |
| YME1L1 | ANKRD13C | 0.675796 | 4 | 0 | 3 |
| YME1L1 | FCHO2 | 0.673604 | 5 | 0 | 4 |
| YME1L1 | HOOK3 | 0.670357 | 4 | 0 | 3 |
| YME1L1 | NDUFS1 | 0.669057 | 4 | 0 | 3 |
For details and further investigation, click here
