MRPS11

 

Full name: mitochondrial ribosomal protein S11 Alias Symbol: FLJ23406|HCC-2|FLJ22512
Type: protein-coding gene Cytoband: 15q25.3
Entrez ID: 64963 HGNC ID: HGNC:14050 Ensembl Gene: ENSG00000181991 OMIM ID: 611977
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of MRPS11:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 MRPS11 64963 211595_s_at -0.0029 0.9966
GSE20347 MRPS11 64963 211595_s_at 0.2260 0.1310
GSE23400 MRPS11 64963 211595_s_at 0.0580 0.2288
GSE26886 MRPS11 64963 211595_s_at -0.1484 0.3583
GSE29001 MRPS11 64963 211595_s_at 0.0097 0.9796
GSE38129 MRPS11 64963 211595_s_at 0.3380 0.0055
GSE45670 MRPS11 64963 211595_s_at 0.2858 0.1621
GSE63941 MRPS11 64963 211595_s_at 0.0846 0.8572
GSE77861 MRPS11 64963 211595_s_at -0.1587 0.4606
GSE97050 MRPS11 64963 A_23_P48977 -0.1346 0.4638
SRP007169 MRPS11 64963 RNAseq -0.5698 0.1024
SRP008496 MRPS11 64963 RNAseq -1.1181 0.0000
SRP064894 MRPS11 64963 RNAseq 0.3725 0.1184
SRP133303 MRPS11 64963 RNAseq 0.1246 0.4369
SRP159526 MRPS11 64963 RNAseq -0.0201 0.8816
SRP193095 MRPS11 64963 RNAseq -0.1925 0.0154
SRP219564 MRPS11 64963 RNAseq 0.0766 0.8010
TCGA MRPS11 64963 RNAseq 0.0668 0.2292

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by MRPS11 expression:

 

TCGA

 

Note: Click image to view full size file.  


Copy number change of MRPS11:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 MRPS11 64963 7 3 20
GSE20123 MRPS11 64963 7 3 20
GSE43470 MRPS11 64963 5 4 34
GSE46452 MRPS11 64963 3 7 49
GSE47630 MRPS11 64963 8 10 22
GSE54993 MRPS11 64963 4 6 60
GSE54994 MRPS11 64963 7 6 40
GSE60625 MRPS11 64963 4 0 7
GSE74703 MRPS11 64963 4 3 29
GSE74704 MRPS11 64963 4 2 14
TCGA MRPS11 64963 16 12 68

Total number of gains: 69; Total number of losses: 56; Total Number of normals: 363.  


 

Somatic mutations of MRPS11:

 

Generating mutation plots.

 

Highly correlated genes for MRPS11:

 

Showing top 20/371 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
MRPS11RPS27A0.798531303
MRPS11CTR90.787576303
MRPS11CASP40.775844303
MRPS11DENND4A0.770931303
MRPS11TUFM0.764808303
MRPS11FBXO110.755688303
MRPS11SUMO30.748236303
MRPS11ATIC0.746675303
MRPS11FEM1B0.738886303
MRPS11TMEM126A0.730408303
MRPS11MRPL460.72845711010
MRPS11TUBGCP40.724285403
MRPS11VPS26A0.723591404
MRPS11SRBD10.723553303
MRPS11PFDN50.721556303
MRPS11FDX10.720392303
MRPS11PSMC40.720116303
MRPS11MITD10.715665303
MRPS11PNPLA40.71554403
MRPS11ATP6V1E10.713716403

For details and further investigation, click here