| Full name: peroxiredoxin 2 | Alias Symbol: PRP|NKEFB|TSA|PRXII|PRX2|MGC4104 | ||
| Type: protein-coding gene | Cytoband: 19p13.13 | ||
| Entrez ID: 7001 | HGNC ID: HGNC:9353 | Ensembl Gene: ENSG00000167815 | OMIM ID: 600538 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of PRDX2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRDX2 | 7001 | 39729_at | -0.3472 | 0.4507 | |
| GSE20347 | PRDX2 | 7001 | 39729_at | -0.5512 | 0.0011 | |
| GSE23400 | PRDX2 | 7001 | 39729_at | -0.3916 | 0.0004 | |
| GSE26886 | PRDX2 | 7001 | 39729_at | -0.0738 | 0.8531 | |
| GSE29001 | PRDX2 | 7001 | 39729_at | -0.8611 | 0.1015 | |
| GSE38129 | PRDX2 | 7001 | 39729_at | -0.3496 | 0.0108 | |
| GSE45670 | PRDX2 | 7001 | 39729_at | -0.2343 | 0.2856 | |
| GSE53622 | PRDX2 | 7001 | 7741 | -0.4255 | 0.0001 | |
| GSE53624 | PRDX2 | 7001 | 7741 | -0.3636 | 0.0000 | |
| GSE63941 | PRDX2 | 7001 | 39729_at | -0.2748 | 0.8644 | |
| GSE77861 | PRDX2 | 7001 | 39729_at | -0.7588 | 0.2880 | |
| GSE97050 | PRDX2 | 7001 | A_24_P168416 | -0.7343 | 0.0781 | |
| SRP007169 | PRDX2 | 7001 | RNAseq | -0.3931 | 0.2912 | |
| SRP008496 | PRDX2 | 7001 | RNAseq | -0.2075 | 0.3991 | |
| SRP064894 | PRDX2 | 7001 | RNAseq | -0.2132 | 0.4621 | |
| SRP133303 | PRDX2 | 7001 | RNAseq | -0.7400 | 0.0378 | |
| SRP159526 | PRDX2 | 7001 | RNAseq | -0.0998 | 0.5841 | |
| SRP193095 | PRDX2 | 7001 | RNAseq | -0.7261 | 0.0000 | |
| SRP219564 | PRDX2 | 7001 | RNAseq | -0.4737 | 0.4616 | |
| TCGA | PRDX2 | 7001 | RNAseq | -0.0807 | 0.2413 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PRDX2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRDX2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRDX2 | 7001 | 4 | 2 | 24 | |
| GSE20123 | PRDX2 | 7001 | 3 | 1 | 26 | |
| GSE43470 | PRDX2 | 7001 | 2 | 6 | 35 | |
| GSE46452 | PRDX2 | 7001 | 47 | 1 | 11 | |
| GSE47630 | PRDX2 | 7001 | 4 | 7 | 29 | |
| GSE54993 | PRDX2 | 7001 | 16 | 3 | 51 | |
| GSE54994 | PRDX2 | 7001 | 6 | 13 | 34 | |
| GSE60625 | PRDX2 | 7001 | 9 | 0 | 2 | |
| GSE74703 | PRDX2 | 7001 | 2 | 4 | 30 | |
| GSE74704 | PRDX2 | 7001 | 0 | 1 | 19 | |
| TCGA | PRDX2 | 7001 | 16 | 13 | 67 |
Total number of gains: 109; Total number of losses: 51; Total Number of normals: 328.
Somatic mutations of PRDX2:
Generating mutation plots.
Highly correlated genes for PRDX2:
Showing top 20/368 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRDX2 | YAP1 | 0.797682 | 3 | 0 | 3 |
| PRDX2 | NSMCE4A | 0.781062 | 3 | 0 | 3 |
| PRDX2 | TPRG1L | 0.77303 | 3 | 0 | 3 |
| PRDX2 | TAB3 | 0.745273 | 3 | 0 | 3 |
| PRDX2 | SPTBN1 | 0.742923 | 3 | 0 | 3 |
| PRDX2 | SNAPC5 | 0.734439 | 3 | 0 | 3 |
| PRDX2 | AIFM1 | 0.72641 | 3 | 0 | 3 |
| PRDX2 | MRPL38 | 0.724254 | 3 | 0 | 3 |
| PRDX2 | LMBRD2 | 0.722373 | 3 | 0 | 3 |
| PRDX2 | TRAPPC8 | 0.717789 | 3 | 0 | 3 |
| PRDX2 | FKBP2 | 0.716342 | 3 | 0 | 3 |
| PRDX2 | PKN2 | 0.7026 | 3 | 0 | 3 |
| PRDX2 | PCBP2 | 0.701389 | 4 | 0 | 4 |
| PRDX2 | NTN4 | 0.694908 | 3 | 0 | 3 |
| PRDX2 | TUFM | 0.694456 | 3 | 0 | 3 |
| PRDX2 | VPS26A | 0.693378 | 5 | 0 | 4 |
| PRDX2 | PNKD | 0.693042 | 4 | 0 | 3 |
| PRDX2 | ARAP1 | 0.693035 | 3 | 0 | 3 |
| PRDX2 | OCM2 | 0.690711 | 3 | 0 | 3 |
| PRDX2 | APPBP2 | 0.690471 | 4 | 0 | 3 |
For details and further investigation, click here
