| Full name: protein phosphatase 2 regulatory subunit B'epsilon | Alias Symbol: B56E|B56epsilon | ||
| Type: protein-coding gene | Cytoband: 14q23.2 | ||
| Entrez ID: 5529 | HGNC ID: HGNC:9313 | Ensembl Gene: ENSG00000154001 | OMIM ID: 601647 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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PPP2R5E involved pathways:
Expression of PPP2R5E:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PPP2R5E | 5529 | 203338_at | -0.0152 | 0.9864 | |
| GSE20347 | PPP2R5E | 5529 | 203338_at | -0.2188 | 0.2059 | |
| GSE23400 | PPP2R5E | 5529 | 203338_at | -0.0009 | 0.9926 | |
| GSE26886 | PPP2R5E | 5529 | 203338_at | -0.7289 | 0.0012 | |
| GSE29001 | PPP2R5E | 5529 | 203338_at | -0.4235 | 0.3646 | |
| GSE38129 | PPP2R5E | 5529 | 203338_at | -0.1932 | 0.2952 | |
| GSE45670 | PPP2R5E | 5529 | 203338_at | -0.0249 | 0.8875 | |
| GSE53622 | PPP2R5E | 5529 | 33849 | 0.1752 | 0.0234 | |
| GSE53624 | PPP2R5E | 5529 | 33849 | 0.1437 | 0.0088 | |
| GSE63941 | PPP2R5E | 5529 | 203338_at | -0.0987 | 0.7966 | |
| GSE77861 | PPP2R5E | 5529 | 203338_at | -0.0149 | 0.9715 | |
| GSE97050 | PPP2R5E | 5529 | A_23_P3042 | -0.0703 | 0.8782 | |
| SRP007169 | PPP2R5E | 5529 | RNAseq | -0.1289 | 0.6805 | |
| SRP008496 | PPP2R5E | 5529 | RNAseq | -0.0886 | 0.6746 | |
| SRP064894 | PPP2R5E | 5529 | RNAseq | -0.0475 | 0.7362 | |
| SRP133303 | PPP2R5E | 5529 | RNAseq | 0.1530 | 0.3912 | |
| SRP159526 | PPP2R5E | 5529 | RNAseq | -0.1499 | 0.6768 | |
| SRP193095 | PPP2R5E | 5529 | RNAseq | -0.2279 | 0.0384 | |
| SRP219564 | PPP2R5E | 5529 | RNAseq | -0.1604 | 0.5776 | |
| TCGA | PPP2R5E | 5529 | RNAseq | 0.0991 | 0.0565 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PPP2R5E expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PPP2R5E:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PPP2R5E | 5529 | 7 | 3 | 20 | |
| GSE20123 | PPP2R5E | 5529 | 7 | 3 | 20 | |
| GSE43470 | PPP2R5E | 5529 | 8 | 2 | 33 | |
| GSE46452 | PPP2R5E | 5529 | 16 | 3 | 40 | |
| GSE47630 | PPP2R5E | 5529 | 11 | 9 | 20 | |
| GSE54993 | PPP2R5E | 5529 | 3 | 9 | 58 | |
| GSE54994 | PPP2R5E | 5529 | 18 | 5 | 30 | |
| GSE60625 | PPP2R5E | 5529 | 0 | 2 | 9 | |
| GSE74703 | PPP2R5E | 5529 | 7 | 2 | 27 | |
| GSE74704 | PPP2R5E | 5529 | 3 | 2 | 15 | |
| TCGA | PPP2R5E | 5529 | 32 | 14 | 50 |
Total number of gains: 112; Total number of losses: 54; Total Number of normals: 322.
Somatic mutations of PPP2R5E:
Generating mutation plots.
Highly correlated genes for PPP2R5E:
Showing top 20/498 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PPP2R5E | TBC1D23 | 0.805489 | 3 | 0 | 3 |
| PPP2R5E | DDX20 | 0.798646 | 3 | 0 | 3 |
| PPP2R5E | UBE2E2 | 0.797265 | 3 | 0 | 3 |
| PPP2R5E | RNF144B | 0.790749 | 4 | 0 | 4 |
| PPP2R5E | ATG3 | 0.782661 | 3 | 0 | 3 |
| PPP2R5E | NOTCH2 | 0.769426 | 3 | 0 | 3 |
| PPP2R5E | HERC4 | 0.763787 | 3 | 0 | 3 |
| PPP2R5E | RBM7 | 0.759708 | 3 | 0 | 3 |
| PPP2R5E | ARL6IP5 | 0.756403 | 3 | 0 | 3 |
| PPP2R5E | BTF3L4 | 0.751843 | 3 | 0 | 3 |
| PPP2R5E | MTO1 | 0.751688 | 3 | 0 | 3 |
| PPP2R5E | TLE4 | 0.748517 | 3 | 0 | 3 |
| PPP2R5E | LZIC | 0.745496 | 4 | 0 | 3 |
| PPP2R5E | OXNAD1 | 0.744565 | 3 | 0 | 3 |
| PPP2R5E | FRA10AC1 | 0.741904 | 3 | 0 | 3 |
| PPP2R5E | TNPO3 | 0.739786 | 3 | 0 | 3 |
| PPP2R5E | RPS19 | 0.739053 | 3 | 0 | 3 |
| PPP2R5E | MRPS10 | 0.731367 | 3 | 0 | 3 |
| PPP2R5E | DNAJA2 | 0.729676 | 4 | 0 | 4 |
| PPP2R5E | ZNF518A | 0.728268 | 3 | 0 | 3 |
For details and further investigation, click here
