| Full name: mitochondrial ribosomal protein L36 | Alias Symbol: BRIP1|RPMJ|L36mt|PRPL36|MRP-L36 | ||
| Type: protein-coding gene | Cytoband: 5p15.33 | ||
| Entrez ID: 64979 | HGNC ID: HGNC:14490 | Ensembl Gene: ENSG00000171421 | OMIM ID: 611842 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of MRPL36:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRPL36 | 64979 | 224331_s_at | 0.5164 | 0.0383 | |
| GSE26886 | MRPL36 | 64979 | 224331_s_at | 1.1570 | 0.0000 | |
| GSE45670 | MRPL36 | 64979 | 224331_s_at | 0.4357 | 0.0019 | |
| GSE53622 | MRPL36 | 64979 | 8577 | 0.5782 | 0.0000 | |
| GSE53624 | MRPL36 | 64979 | 8577 | 0.6804 | 0.0000 | |
| GSE63941 | MRPL36 | 64979 | 224331_s_at | 0.5583 | 0.0577 | |
| GSE77861 | MRPL36 | 64979 | 224331_s_at | 0.3786 | 0.2973 | |
| GSE97050 | MRPL36 | 64979 | A_24_P371758 | 0.9120 | 0.0726 | |
| SRP007169 | MRPL36 | 64979 | RNAseq | 0.3288 | 0.4780 | |
| SRP008496 | MRPL36 | 64979 | RNAseq | 0.3138 | 0.3438 | |
| SRP064894 | MRPL36 | 64979 | RNAseq | 0.0264 | 0.9181 | |
| SRP133303 | MRPL36 | 64979 | RNAseq | 0.6188 | 0.0048 | |
| SRP159526 | MRPL36 | 64979 | RNAseq | 0.6981 | 0.0025 | |
| SRP193095 | MRPL36 | 64979 | RNAseq | 0.1342 | 0.4589 | |
| SRP219564 | MRPL36 | 64979 | RNAseq | 0.3780 | 0.4584 | |
| TCGA | MRPL36 | 64979 | RNAseq | 0.3206 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by MRPL36 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRPL36:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRPL36 | 64979 | 13 | 1 | 16 | |
| GSE20123 | MRPL36 | 64979 | 13 | 1 | 16 | |
| GSE43470 | MRPL36 | 64979 | 17 | 1 | 25 | |
| GSE46452 | MRPL36 | 64979 | 6 | 22 | 31 | |
| GSE47630 | MRPL36 | 64979 | 6 | 11 | 23 | |
| GSE54993 | MRPL36 | 64979 | 5 | 5 | 60 | |
| GSE54994 | MRPL36 | 64979 | 29 | 1 | 23 | |
| GSE60625 | MRPL36 | 64979 | 0 | 0 | 11 | |
| GSE74703 | MRPL36 | 64979 | 14 | 0 | 22 | |
| GSE74704 | MRPL36 | 64979 | 11 | 0 | 9 | |
| TCGA | MRPL36 | 64979 | 59 | 3 | 34 |
Total number of gains: 173; Total number of losses: 45; Total Number of normals: 270.
Somatic mutations of MRPL36:
Generating mutation plots.
Highly correlated genes for MRPL36:
Showing top 20/1503 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRPL36 | ADCY3 | 0.925491 | 3 | 0 | 3 |
| MRPL36 | SEMA4C | 0.805358 | 3 | 0 | 3 |
| MRPL36 | FXR1 | 0.79155 | 4 | 0 | 4 |
| MRPL36 | INTS10 | 0.781737 | 3 | 0 | 3 |
| MRPL36 | SNAPC2 | 0.772478 | 3 | 0 | 3 |
| MRPL36 | CUTA | 0.768496 | 3 | 0 | 3 |
| MRPL36 | WIZ | 0.76709 | 3 | 0 | 3 |
| MRPL36 | NENF | 0.762356 | 4 | 0 | 4 |
| MRPL36 | MEA1 | 0.760425 | 4 | 0 | 4 |
| MRPL36 | FIP1L1 | 0.758735 | 3 | 0 | 3 |
| MRPL36 | GEMIN5 | 0.756516 | 3 | 0 | 3 |
| MRPL36 | NDUFS6 | 0.756349 | 8 | 0 | 8 |
| MRPL36 | DGKD | 0.7563 | 3 | 0 | 3 |
| MRPL36 | RAD23A | 0.755325 | 3 | 0 | 3 |
| MRPL36 | MRPL47 | 0.751466 | 7 | 0 | 7 |
| MRPL36 | MAN2B1 | 0.749715 | 3 | 0 | 3 |
| MRPL36 | ACLY | 0.747298 | 6 | 0 | 6 |
| MRPL36 | ZBED1 | 0.745638 | 3 | 0 | 3 |
| MRPL36 | PCYT1A | 0.744271 | 4 | 0 | 4 |
| MRPL36 | JMJD4 | 0.743214 | 3 | 0 | 3 |
For details and further investigation, click here
