| Full name: zinc finger protein 689 | Alias Symbol: FLJ90415|TIPUH1 | ||
| Type: protein-coding gene | Cytoband: 16p11.2 | ||
| Entrez ID: 115509 | HGNC ID: HGNC:25173 | Ensembl Gene: ENSG00000156853 | OMIM ID: 618033 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF689:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF689 | 115509 | 227294_at | 0.1918 | 0.7302 | |
| GSE26886 | ZNF689 | 115509 | 227294_at | 0.6303 | 0.0054 | |
| GSE45670 | ZNF689 | 115509 | 227294_at | 0.1959 | 0.2233 | |
| GSE53622 | ZNF689 | 115509 | 30006 | 0.5402 | 0.0000 | |
| GSE53624 | ZNF689 | 115509 | 30006 | 0.6242 | 0.0000 | |
| GSE63941 | ZNF689 | 115509 | 227445_at | 0.4228 | 0.2182 | |
| GSE77861 | ZNF689 | 115509 | 227294_at | 0.2118 | 0.1396 | |
| GSE97050 | ZNF689 | 115509 | A_23_P129659 | 0.2586 | 0.3752 | |
| SRP007169 | ZNF689 | 115509 | RNAseq | 0.5184 | 0.4109 | |
| SRP064894 | ZNF689 | 115509 | RNAseq | 0.4199 | 0.0495 | |
| SRP133303 | ZNF689 | 115509 | RNAseq | 0.4698 | 0.0312 | |
| SRP159526 | ZNF689 | 115509 | RNAseq | 0.6064 | 0.0176 | |
| SRP193095 | ZNF689 | 115509 | RNAseq | 0.4223 | 0.0021 | |
| SRP219564 | ZNF689 | 115509 | RNAseq | 0.3321 | 0.4212 | |
| TCGA | ZNF689 | 115509 | RNAseq | -0.1254 | 0.0897 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZNF689 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF689:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF689 | 115509 | 5 | 5 | 20 | |
| GSE20123 | ZNF689 | 115509 | 5 | 4 | 21 | |
| GSE43470 | ZNF689 | 115509 | 3 | 3 | 37 | |
| GSE46452 | ZNF689 | 115509 | 38 | 1 | 20 | |
| GSE47630 | ZNF689 | 115509 | 11 | 7 | 22 | |
| GSE54993 | ZNF689 | 115509 | 2 | 5 | 63 | |
| GSE54994 | ZNF689 | 115509 | 5 | 9 | 39 | |
| GSE60625 | ZNF689 | 115509 | 4 | 0 | 7 | |
| GSE74703 | ZNF689 | 115509 | 3 | 2 | 31 | |
| GSE74704 | ZNF689 | 115509 | 3 | 2 | 15 | |
| TCGA | ZNF689 | 115509 | 20 | 10 | 66 |
Total number of gains: 99; Total number of losses: 48; Total Number of normals: 341.
Somatic mutations of ZNF689:
Generating mutation plots.
Highly correlated genes for ZNF689:
Showing top 20/771 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF689 | STOML1 | 0.86255 | 3 | 0 | 3 |
| ZNF689 | RCN2 | 0.857686 | 3 | 0 | 3 |
| ZNF689 | REPIN1 | 0.794382 | 3 | 0 | 3 |
| ZNF689 | MTFMT | 0.792446 | 3 | 0 | 3 |
| ZNF689 | DHX40 | 0.769801 | 3 | 0 | 3 |
| ZNF689 | RUNDC1 | 0.764517 | 3 | 0 | 3 |
| ZNF689 | DNAJC19 | 0.755892 | 3 | 0 | 3 |
| ZNF689 | ADH5 | 0.754635 | 3 | 0 | 3 |
| ZNF689 | GEMIN5 | 0.754436 | 3 | 0 | 3 |
| ZNF689 | CTPS2 | 0.75442 | 3 | 0 | 3 |
| ZNF689 | WIZ | 0.73989 | 3 | 0 | 3 |
| ZNF689 | FAM20B | 0.739271 | 3 | 0 | 3 |
| ZNF689 | TUFM | 0.73811 | 4 | 0 | 4 |
| ZNF689 | GMCL1 | 0.734609 | 4 | 0 | 3 |
| ZNF689 | POLA1 | 0.731821 | 3 | 0 | 3 |
| ZNF689 | SFT2D3 | 0.727332 | 4 | 0 | 4 |
| ZNF689 | ERCC2 | 0.725454 | 3 | 0 | 3 |
| ZNF689 | CDKN1C | 0.721226 | 3 | 0 | 3 |
| ZNF689 | ORC1 | 0.71773 | 3 | 0 | 3 |
| ZNF689 | USF1 | 0.717638 | 3 | 0 | 3 |
For details and further investigation, click here
