| Full name: growth hormone releasing hormone | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 20q11.23 | ||
| Entrez ID: 2691 | HGNC ID: HGNC:4265 | Ensembl Gene: ENSG00000118702 | OMIM ID: 139190 |
| Drug and gene relationship at DGIdb | |||
Expression of GHRH:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GHRH | 2691 | 214524_at | -0.2073 | 0.3298 | |
| GSE20347 | GHRH | 2691 | 214524_at | -0.1688 | 0.0210 | |
| GSE23400 | GHRH | 2691 | 214524_at | -0.2293 | 0.0000 | |
| GSE26886 | GHRH | 2691 | 214524_at | -0.0405 | 0.7987 | |
| GSE29001 | GHRH | 2691 | 214524_at | -0.1244 | 0.5532 | |
| GSE38129 | GHRH | 2691 | 214524_at | -0.2583 | 0.0038 | |
| GSE45670 | GHRH | 2691 | 214524_at | -0.0481 | 0.7040 | |
| GSE53622 | GHRH | 2691 | 62572 | 0.3407 | 0.0257 | |
| GSE53624 | GHRH | 2691 | 62572 | 0.1622 | 0.3231 | |
| GSE63941 | GHRH | 2691 | 214524_at | 0.2114 | 0.8480 | |
| GSE77861 | GHRH | 2691 | 214524_at | -0.1336 | 0.3058 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GHRH expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GHRH:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GHRH | 2691 | 14 | 2 | 14 | |
| GSE20123 | GHRH | 2691 | 14 | 2 | 14 | |
| GSE43470 | GHRH | 2691 | 13 | 0 | 30 | |
| GSE46452 | GHRH | 2691 | 29 | 0 | 30 | |
| GSE47630 | GHRH | 2691 | 24 | 0 | 16 | |
| GSE54993 | GHRH | 2691 | 0 | 17 | 53 | |
| GSE54994 | GHRH | 2691 | 23 | 0 | 30 | |
| GSE60625 | GHRH | 2691 | 0 | 0 | 11 | |
| GSE74703 | GHRH | 2691 | 11 | 0 | 25 | |
| GSE74704 | GHRH | 2691 | 10 | 1 | 9 | |
| TCGA | GHRH | 2691 | 47 | 3 | 46 |
Total number of gains: 185; Total number of losses: 25; Total Number of normals: 278.
Somatic mutations of GHRH:
Generating mutation plots.
Highly correlated genes for GHRH:
Showing top 20/533 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GHRH | IQCF2 | 0.679167 | 3 | 0 | 3 |
| GHRH | RPL34 | 0.656998 | 3 | 0 | 3 |
| GHRH | SLC6A5 | 0.653564 | 3 | 0 | 3 |
| GHRH | C10orf71-AS1 | 0.649988 | 3 | 0 | 3 |
| GHRH | FUT5 | 0.647654 | 7 | 0 | 6 |
| GHRH | AMACR | 0.629653 | 5 | 0 | 4 |
| GHRH | IGH | 0.629025 | 6 | 0 | 4 |
| GHRH | MYO7A | 0.627256 | 3 | 0 | 3 |
| GHRH | PNMA3 | 0.626983 | 6 | 0 | 6 |
| GHRH | CCIN | 0.626872 | 8 | 0 | 7 |
| GHRH | TSHR | 0.625046 | 3 | 0 | 3 |
| GHRH | CGA | 0.624549 | 3 | 0 | 3 |
| GHRH | CPED1 | 0.622245 | 3 | 0 | 3 |
| GHRH | CACNG2 | 0.622208 | 3 | 0 | 3 |
| GHRH | TPPP | 0.622045 | 4 | 0 | 3 |
| GHRH | HLA-DOA | 0.617136 | 6 | 0 | 5 |
| GHRH | PTTG2 | 0.615923 | 3 | 0 | 3 |
| GHRH | TAPT1 | 0.615669 | 4 | 0 | 3 |
| GHRH | CACNB4 | 0.615638 | 5 | 0 | 4 |
| GHRH | RHBG | 0.614146 | 7 | 0 | 5 |
For details and further investigation, click here
