| Full name: gastric inhibitory polypeptide receptor | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19q13.32 | ||
| Entrez ID: 2696 | HGNC ID: HGNC:4271 | Ensembl Gene: ENSG00000010310 | OMIM ID: 137241 |
| Drug and gene relationship at DGIdb | |||
GIPR involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04024 | cAMP signaling pathway |
Expression of GIPR:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GIPR | 2696 | 231291_at | -0.1074 | 0.6354 | |
| GSE20347 | GIPR | 2696 | 208105_at | -0.1009 | 0.1091 | |
| GSE23400 | GIPR | 2696 | 208105_at | -0.1340 | 0.0000 | |
| GSE26886 | GIPR | 2696 | 231291_at | -0.2278 | 0.0168 | |
| GSE29001 | GIPR | 2696 | 208105_at | -0.2000 | 0.0481 | |
| GSE38129 | GIPR | 2696 | 208105_at | -0.1655 | 0.0241 | |
| GSE45670 | GIPR | 2696 | 231291_at | 0.1544 | 0.2275 | |
| GSE53622 | GIPR | 2696 | 58589 | 0.1161 | 0.2652 | |
| GSE53624 | GIPR | 2696 | 58589 | 0.1252 | 0.0924 | |
| GSE63941 | GIPR | 2696 | 231291_at | 0.0836 | 0.5783 | |
| GSE77861 | GIPR | 2696 | 231291_at | -0.0686 | 0.5529 | |
| GSE97050 | GIPR | 2696 | A_24_P373768 | 0.0329 | 0.8830 | |
| SRP064894 | GIPR | 2696 | RNAseq | 0.0270 | 0.9313 | |
| SRP133303 | GIPR | 2696 | RNAseq | -0.0411 | 0.8479 | |
| SRP159526 | GIPR | 2696 | RNAseq | -0.0474 | 0.9270 | |
| SRP193095 | GIPR | 2696 | RNAseq | -0.1637 | 0.4899 | |
| SRP219564 | GIPR | 2696 | RNAseq | -0.3692 | 0.7335 | |
| TCGA | GIPR | 2696 | RNAseq | -1.2018 | 0.0046 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by GIPR expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GIPR:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GIPR | 2696 | 4 | 5 | 21 | |
| GSE20123 | GIPR | 2696 | 4 | 4 | 22 | |
| GSE43470 | GIPR | 2696 | 3 | 11 | 29 | |
| GSE46452 | GIPR | 2696 | 45 | 1 | 13 | |
| GSE47630 | GIPR | 2696 | 8 | 7 | 25 | |
| GSE54993 | GIPR | 2696 | 17 | 4 | 49 | |
| GSE54994 | GIPR | 2696 | 5 | 13 | 35 | |
| GSE60625 | GIPR | 2696 | 9 | 0 | 2 | |
| GSE74703 | GIPR | 2696 | 3 | 7 | 26 | |
| GSE74704 | GIPR | 2696 | 4 | 2 | 14 | |
| TCGA | GIPR | 2696 | 16 | 15 | 65 |
Total number of gains: 118; Total number of losses: 69; Total Number of normals: 301.
Somatic mutations of GIPR:
Generating mutation plots.
Highly correlated genes for GIPR:
Showing top 20/553 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GIPR | MRGPRG | 0.765198 | 3 | 0 | 3 |
| GIPR | STRC | 0.76326 | 3 | 0 | 3 |
| GIPR | PABPN1L | 0.75606 | 3 | 0 | 3 |
| GIPR | SLC22A25 | 0.753806 | 3 | 0 | 3 |
| GIPR | PRSS38 | 0.752473 | 3 | 0 | 3 |
| GIPR | C1QL2 | 0.743493 | 3 | 0 | 3 |
| GIPR | GUCY2C | 0.739388 | 3 | 0 | 3 |
| GIPR | C9orf153 | 0.731832 | 3 | 0 | 3 |
| GIPR | YY2 | 0.730633 | 3 | 0 | 3 |
| GIPR | GRXCR2 | 0.727192 | 3 | 0 | 3 |
| GIPR | TSPAN11 | 0.72568 | 4 | 0 | 4 |
| GIPR | LHB | 0.718113 | 3 | 0 | 3 |
| GIPR | PLA2G2C | 0.714883 | 3 | 0 | 3 |
| GIPR | RNF180 | 0.713051 | 3 | 0 | 3 |
| GIPR | DCDC1 | 0.712614 | 3 | 0 | 3 |
| GIPR | NKX6-3 | 0.712599 | 4 | 0 | 4 |
| GIPR | TCTE1 | 0.711272 | 3 | 0 | 3 |
| GIPR | SLC6A18 | 0.705495 | 4 | 0 | 3 |
| GIPR | BSX | 0.702802 | 3 | 0 | 3 |
| GIPR | TGM7 | 0.702457 | 3 | 0 | 3 |
For details and further investigation, click here
