| Full name: tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | Alias Symbol: KIAA1728|ROLSB | ||
| Type: protein-coding gene | Cytoband: 2q24.2 | ||
| Entrez ID: 85461 | HGNC ID: HGNC:29364 | Ensembl Gene: ENSG00000115183 | OMIM ID: 611397 |
| Drug and gene relationship at DGIdb | |||
Expression of TANC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TANC1 | 85461 | 225308_s_at | -0.2454 | 0.7019 | |
| GSE26886 | TANC1 | 85461 | 225308_s_at | -0.5127 | 0.0264 | |
| GSE45670 | TANC1 | 85461 | 225308_s_at | -0.4225 | 0.0286 | |
| GSE53622 | TANC1 | 85461 | 63700 | -0.2623 | 0.0006 | |
| GSE53624 | TANC1 | 85461 | 63700 | -0.2825 | 0.0000 | |
| GSE63941 | TANC1 | 85461 | 225308_s_at | -0.6595 | 0.1013 | |
| GSE77861 | TANC1 | 85461 | 225308_s_at | -0.0865 | 0.7310 | |
| GSE97050 | TANC1 | 85461 | A_32_P135348 | -0.6526 | 0.0903 | |
| SRP007169 | TANC1 | 85461 | RNAseq | 0.2114 | 0.6459 | |
| SRP008496 | TANC1 | 85461 | RNAseq | 0.3164 | 0.2177 | |
| SRP064894 | TANC1 | 85461 | RNAseq | -0.4974 | 0.0541 | |
| SRP133303 | TANC1 | 85461 | RNAseq | -0.1192 | 0.2714 | |
| SRP159526 | TANC1 | 85461 | RNAseq | -0.4659 | 0.0193 | |
| SRP193095 | TANC1 | 85461 | RNAseq | -0.2137 | 0.1358 | |
| SRP219564 | TANC1 | 85461 | RNAseq | -0.7159 | 0.0637 | |
| TCGA | TANC1 | 85461 | RNAseq | -0.0220 | 0.6719 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TANC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TANC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TANC1 | 85461 | 5 | 1 | 24 | |
| GSE20123 | TANC1 | 85461 | 5 | 1 | 24 | |
| GSE43470 | TANC1 | 85461 | 4 | 1 | 38 | |
| GSE46452 | TANC1 | 85461 | 1 | 4 | 54 | |
| GSE47630 | TANC1 | 85461 | 5 | 3 | 32 | |
| GSE54993 | TANC1 | 85461 | 0 | 4 | 66 | |
| GSE54994 | TANC1 | 85461 | 11 | 2 | 40 | |
| GSE60625 | TANC1 | 85461 | 0 | 3 | 8 | |
| GSE74703 | TANC1 | 85461 | 3 | 1 | 32 | |
| GSE74704 | TANC1 | 85461 | 3 | 0 | 17 | |
| TCGA | TANC1 | 85461 | 24 | 9 | 63 |
Total number of gains: 61; Total number of losses: 29; Total Number of normals: 398.
Somatic mutations of TANC1:
Generating mutation plots.
Highly correlated genes for TANC1:
Showing top 20/347 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TANC1 | GLYR1 | 0.819352 | 3 | 0 | 3 |
| TANC1 | NAA35 | 0.787034 | 3 | 0 | 3 |
| TANC1 | UBE2B | 0.786238 | 3 | 0 | 3 |
| TANC1 | RNF111 | 0.781362 | 3 | 0 | 3 |
| TANC1 | ZCCHC10 | 0.778448 | 4 | 0 | 4 |
| TANC1 | MRFAP1L1 | 0.772601 | 3 | 0 | 3 |
| TANC1 | VTI1B | 0.772496 | 3 | 0 | 3 |
| TANC1 | USP38 | 0.768558 | 3 | 0 | 3 |
| TANC1 | RNF146 | 0.768098 | 3 | 0 | 3 |
| TANC1 | CBLL1 | 0.765542 | 3 | 0 | 3 |
| TANC1 | HDHD2 | 0.758191 | 3 | 0 | 3 |
| TANC1 | CPEB2 | 0.752975 | 4 | 0 | 4 |
| TANC1 | CNOT6 | 0.746863 | 3 | 0 | 3 |
| TANC1 | LIMCH1 | 0.744073 | 3 | 0 | 3 |
| TANC1 | EIF5 | 0.741153 | 3 | 0 | 3 |
| TANC1 | SIPA1L2 | 0.740904 | 4 | 0 | 4 |
| TANC1 | NIPAL3 | 0.740456 | 3 | 0 | 3 |
| TANC1 | MTRF1 | 0.731175 | 3 | 0 | 3 |
| TANC1 | PLEKHF2 | 0.731089 | 3 | 0 | 3 |
| TANC1 | DNAJA2 | 0.730345 | 3 | 0 | 3 |
For details and further investigation, click here
