| Full name: LON peptidase N-terminal domain and ring finger 1 | Alias Symbol: FLJ23749|RNF191 | ||
| Type: protein-coding gene | Cytoband: 8p23.1 | ||
| Entrez ID: 91694 | HGNC ID: HGNC:26302 | Ensembl Gene: ENSG00000154359 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LONRF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LONRF1 | 91694 | 226038_at | -0.6366 | 0.3093 | |
| GSE20347 | LONRF1 | 91694 | 215322_at | -0.4329 | 0.1214 | |
| GSE23400 | LONRF1 | 91694 | 215322_at | -0.6597 | 0.0000 | |
| GSE26886 | LONRF1 | 91694 | 226038_at | -0.6332 | 0.0401 | |
| GSE29001 | LONRF1 | 91694 | 215322_at | -0.6632 | 0.0071 | |
| GSE38129 | LONRF1 | 91694 | 215322_at | -0.7182 | 0.0036 | |
| GSE45670 | LONRF1 | 91694 | 226038_at | -1.1694 | 0.0000 | |
| GSE53622 | LONRF1 | 91694 | 116401 | -0.4884 | 0.0001 | |
| GSE53624 | LONRF1 | 91694 | 116401 | -0.6577 | 0.0000 | |
| GSE63941 | LONRF1 | 91694 | 226038_at | -0.4142 | 0.6747 | |
| GSE77861 | LONRF1 | 91694 | 226038_at | 0.2745 | 0.4069 | |
| GSE97050 | LONRF1 | 91694 | A_23_P94216 | -0.9429 | 0.0835 | |
| SRP007169 | LONRF1 | 91694 | RNAseq | -0.1060 | 0.7809 | |
| SRP008496 | LONRF1 | 91694 | RNAseq | 0.1888 | 0.5063 | |
| SRP064894 | LONRF1 | 91694 | RNAseq | -1.3191 | 0.0001 | |
| SRP133303 | LONRF1 | 91694 | RNAseq | -0.8698 | 0.0003 | |
| SRP159526 | LONRF1 | 91694 | RNAseq | 0.2205 | 0.6931 | |
| SRP193095 | LONRF1 | 91694 | RNAseq | -0.5948 | 0.0012 | |
| SRP219564 | LONRF1 | 91694 | RNAseq | -0.8551 | 0.1336 | |
| TCGA | LONRF1 | 91694 | RNAseq | -0.2397 | 0.0145 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by LONRF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LONRF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LONRF1 | 91694 | 4 | 10 | 16 | |
| GSE20123 | LONRF1 | 91694 | 4 | 11 | 15 | |
| GSE43470 | LONRF1 | 91694 | 4 | 9 | 30 | |
| GSE46452 | LONRF1 | 91694 | 12 | 14 | 33 | |
| GSE47630 | LONRF1 | 91694 | 10 | 7 | 23 | |
| GSE54993 | LONRF1 | 91694 | 3 | 14 | 53 | |
| GSE54994 | LONRF1 | 91694 | 8 | 18 | 27 | |
| GSE60625 | LONRF1 | 91694 | 3 | 0 | 8 | |
| GSE74703 | LONRF1 | 91694 | 4 | 7 | 25 | |
| GSE74704 | LONRF1 | 91694 | 3 | 7 | 10 | |
| TCGA | LONRF1 | 91694 | 13 | 41 | 42 |
Total number of gains: 68; Total number of losses: 138; Total Number of normals: 282.
Somatic mutations of LONRF1:
Generating mutation plots.
Highly correlated genes for LONRF1:
Showing top 20/475 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LONRF1 | OCRL | 0.864616 | 3 | 0 | 3 |
| LONRF1 | WDR73 | 0.766062 | 3 | 0 | 3 |
| LONRF1 | AZIN1 | 0.759655 | 3 | 0 | 3 |
| LONRF1 | GLYR1 | 0.74546 | 3 | 0 | 3 |
| LONRF1 | TMEM218 | 0.713892 | 3 | 0 | 3 |
| LONRF1 | TMEM181 | 0.704861 | 3 | 0 | 3 |
| LONRF1 | HOXA4 | 0.701178 | 4 | 0 | 3 |
| LONRF1 | FAM118B | 0.694578 | 3 | 0 | 3 |
| LONRF1 | CFL2 | 0.691613 | 4 | 0 | 3 |
| LONRF1 | NHS | 0.689435 | 3 | 0 | 3 |
| LONRF1 | HYLS1 | 0.687218 | 3 | 0 | 3 |
| LONRF1 | ITGA1 | 0.681695 | 3 | 0 | 3 |
| LONRF1 | TLE2 | 0.679413 | 5 | 0 | 5 |
| LONRF1 | KPNA3 | 0.675938 | 4 | 0 | 3 |
| LONRF1 | GFRA1 | 0.674035 | 4 | 0 | 3 |
| LONRF1 | ADAMTS9-AS2 | 0.671466 | 4 | 0 | 4 |
| LONRF1 | KLHL23 | 0.66656 | 5 | 0 | 4 |
| LONRF1 | CAPZA2 | 0.666102 | 3 | 0 | 3 |
| LONRF1 | CDC37L1 | 0.661651 | 4 | 0 | 3 |
| LONRF1 | CRNKL1 | 0.661169 | 3 | 0 | 3 |
For details and further investigation, click here
