| Full name: LUC7 like 2, pre-mRNA splicing factor | Alias Symbol: CGI-74|CGI-59|H_NH0792N18.3|FLJ10657|LUC7B2|hLuc7B2 | ||
| Type: protein-coding gene | Cytoband: 7q34 | ||
| Entrez ID: 51631 | HGNC ID: HGNC:21608 | Ensembl Gene: ENSG00000146963 | OMIM ID: 613056 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of LUC7L2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LUC7L2 | 51631 | 226758_at | 0.0430 | 0.9518 | |
| GSE26886 | LUC7L2 | 51631 | 226758_at | 0.4195 | 0.0378 | |
| GSE45670 | LUC7L2 | 51631 | 226758_at | -0.0704 | 0.6297 | |
| GSE53622 | LUC7L2 | 51631 | 98533 | -0.0626 | 0.3466 | |
| GSE53624 | LUC7L2 | 51631 | 98533 | 0.0716 | 0.2597 | |
| GSE63941 | LUC7L2 | 51631 | 226758_at | -0.3346 | 0.3563 | |
| GSE77861 | LUC7L2 | 51631 | 226758_at | 0.0349 | 0.7763 | |
| GSE97050 | LUC7L2 | 51631 | A_23_P59787 | -0.4143 | 0.2501 | |
| SRP007169 | LUC7L2 | 51631 | RNAseq | 1.4599 | 0.0026 | |
| SRP008496 | LUC7L2 | 51631 | RNAseq | 2.0815 | 0.0000 | |
| SRP064894 | LUC7L2 | 51631 | RNAseq | 0.0882 | 0.8373 | |
| SRP133303 | LUC7L2 | 51631 | RNAseq | -0.0072 | 0.9569 | |
| SRP159526 | LUC7L2 | 51631 | RNAseq | -0.2932 | 0.2245 | |
| SRP193095 | LUC7L2 | 51631 | RNAseq | -0.0325 | 0.7822 | |
| SRP219564 | LUC7L2 | 51631 | RNAseq | -0.5480 | 0.1338 | |
| TCGA | LUC7L2 | 51631 | RNAseq | -0.0032 | 0.9416 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by LUC7L2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LUC7L2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LUC7L2 | 51631 | 5 | 2 | 23 | |
| GSE20123 | LUC7L2 | 51631 | 5 | 2 | 23 | |
| GSE43470 | LUC7L2 | 51631 | 2 | 3 | 38 | |
| GSE46452 | LUC7L2 | 51631 | 7 | 2 | 50 | |
| GSE47630 | LUC7L2 | 51631 | 7 | 4 | 29 | |
| GSE54993 | LUC7L2 | 51631 | 3 | 5 | 62 | |
| GSE54994 | LUC7L2 | 51631 | 5 | 8 | 40 | |
| GSE60625 | LUC7L2 | 51631 | 0 | 0 | 11 | |
| GSE74703 | LUC7L2 | 51631 | 2 | 3 | 31 | |
| GSE74704 | LUC7L2 | 51631 | 1 | 2 | 17 | |
| TCGA | LUC7L2 | 51631 | 28 | 23 | 45 |
Total number of gains: 65; Total number of losses: 54; Total Number of normals: 369.
Somatic mutations of LUC7L2:
Generating mutation plots.
Highly correlated genes for LUC7L2:
Showing top 20/200 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LUC7L2 | SCAF8 | 0.830329 | 3 | 0 | 3 |
| LUC7L2 | NAA60 | 0.804782 | 3 | 0 | 3 |
| LUC7L2 | CEP63 | 0.79752 | 3 | 0 | 3 |
| LUC7L2 | WHAMM | 0.791768 | 3 | 0 | 3 |
| LUC7L2 | OTUD7B | 0.783919 | 3 | 0 | 3 |
| LUC7L2 | MIPOL1 | 0.77896 | 3 | 0 | 3 |
| LUC7L2 | ZNF121 | 0.772891 | 3 | 0 | 3 |
| LUC7L2 | GLYR1 | 0.771226 | 4 | 0 | 3 |
| LUC7L2 | SLC25A40 | 0.771113 | 3 | 0 | 3 |
| LUC7L2 | LRRC47 | 0.770282 | 3 | 0 | 3 |
| LUC7L2 | KPNA4 | 0.767439 | 3 | 0 | 3 |
| LUC7L2 | COX6A1 | 0.767218 | 3 | 0 | 3 |
| LUC7L2 | FAM168A | 0.766814 | 3 | 0 | 3 |
| LUC7L2 | RALGAPA1 | 0.766796 | 3 | 0 | 3 |
| LUC7L2 | ZMPSTE24 | 0.766137 | 3 | 0 | 3 |
| LUC7L2 | PTPRA | 0.754075 | 3 | 0 | 3 |
| LUC7L2 | KLHDC2 | 0.747869 | 3 | 0 | 3 |
| LUC7L2 | SLC37A3 | 0.74165 | 4 | 0 | 4 |
| LUC7L2 | IPP | 0.741425 | 3 | 0 | 3 |
| LUC7L2 | TRAPPC8 | 0.734141 | 3 | 0 | 3 |
For details and further investigation, click here
