| Full name: glucocorticoid modulatory element binding protein 1 | Alias Symbol: P96PIF|PIF96 | ||
| Type: protein-coding gene | Cytoband: 1p35.3 | ||
| Entrez ID: 10691 | HGNC ID: HGNC:4370 | Ensembl Gene: ENSG00000162419 | OMIM ID: 604409 |
| Drug and gene relationship at DGIdb | |||
Expression of GMEB1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GMEB1 | 10691 | 235233_s_at | 0.1847 | 0.7178 | |
| GSE20347 | GMEB1 | 10691 | 220938_s_at | -0.1891 | 0.0470 | |
| GSE23400 | GMEB1 | 10691 | 220938_s_at | -0.0430 | 0.2443 | |
| GSE26886 | GMEB1 | 10691 | 235233_s_at | -0.4070 | 0.0922 | |
| GSE29001 | GMEB1 | 10691 | 220938_s_at | -0.1633 | 0.3637 | |
| GSE38129 | GMEB1 | 10691 | 220938_s_at | -0.1105 | 0.3785 | |
| GSE45670 | GMEB1 | 10691 | 235233_s_at | 0.1629 | 0.1286 | |
| GSE53622 | GMEB1 | 10691 | 8472 | -0.0007 | 0.9889 | |
| GSE53624 | GMEB1 | 10691 | 8472 | -0.0628 | 0.1723 | |
| GSE63941 | GMEB1 | 10691 | 235232_at | -0.5681 | 0.1364 | |
| GSE77861 | GMEB1 | 10691 | 220938_s_at | -0.0933 | 0.3251 | |
| GSE97050 | GMEB1 | 10691 | A_23_P137586 | 0.1704 | 0.4924 | |
| SRP007169 | GMEB1 | 10691 | RNAseq | -0.4095 | 0.3485 | |
| SRP008496 | GMEB1 | 10691 | RNAseq | -0.3362 | 0.2206 | |
| SRP064894 | GMEB1 | 10691 | RNAseq | 0.0984 | 0.5255 | |
| SRP133303 | GMEB1 | 10691 | RNAseq | -0.1086 | 0.3339 | |
| SRP159526 | GMEB1 | 10691 | RNAseq | -0.1707 | 0.4526 | |
| SRP193095 | GMEB1 | 10691 | RNAseq | -0.1567 | 0.0096 | |
| SRP219564 | GMEB1 | 10691 | RNAseq | -0.2479 | 0.3266 | |
| TCGA | GMEB1 | 10691 | RNAseq | 0.0719 | 0.2719 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GMEB1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GMEB1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GMEB1 | 10691 | 0 | 6 | 24 | |
| GSE20123 | GMEB1 | 10691 | 0 | 5 | 25 | |
| GSE43470 | GMEB1 | 10691 | 3 | 6 | 34 | |
| GSE46452 | GMEB1 | 10691 | 5 | 1 | 53 | |
| GSE47630 | GMEB1 | 10691 | 8 | 3 | 29 | |
| GSE54993 | GMEB1 | 10691 | 2 | 1 | 67 | |
| GSE54994 | GMEB1 | 10691 | 10 | 4 | 39 | |
| GSE60625 | GMEB1 | 10691 | 0 | 0 | 11 | |
| GSE74703 | GMEB1 | 10691 | 2 | 4 | 30 | |
| GSE74704 | GMEB1 | 10691 | 0 | 0 | 20 | |
| TCGA | GMEB1 | 10691 | 11 | 21 | 64 |
Total number of gains: 41; Total number of losses: 51; Total Number of normals: 396.
Somatic mutations of GMEB1:
Generating mutation plots.
Highly correlated genes for GMEB1:
Showing top 20/43 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GMEB1 | MAT1A | 0.718986 | 3 | 0 | 3 |
| GMEB1 | MBTD1 | 0.688518 | 3 | 0 | 3 |
| GMEB1 | ATP6AP1L | 0.67923 | 3 | 0 | 3 |
| GMEB1 | CYB561D2 | 0.664164 | 3 | 0 | 3 |
| GMEB1 | CYP4Z1 | 0.657117 | 3 | 0 | 3 |
| GMEB1 | CEP104 | 0.636863 | 4 | 0 | 3 |
| GMEB1 | SUMO4 | 0.63164 | 3 | 0 | 3 |
| GMEB1 | STK11 | 0.628359 | 4 | 0 | 3 |
| GMEB1 | SLC37A1 | 0.613963 | 5 | 0 | 4 |
| GMEB1 | USP49 | 0.594009 | 4 | 0 | 3 |
| GMEB1 | DIO2 | 0.592401 | 5 | 0 | 3 |
| GMEB1 | ENTPD5 | 0.590207 | 6 | 0 | 4 |
| GMEB1 | SLC26A2 | 0.58928 | 3 | 0 | 3 |
| GMEB1 | ZNF341 | 0.584718 | 5 | 0 | 3 |
| GMEB1 | TANK | 0.582543 | 5 | 0 | 4 |
| GMEB1 | SAYSD1 | 0.58022 | 3 | 0 | 3 |
| GMEB1 | CAPG | 0.580067 | 3 | 0 | 3 |
| GMEB1 | KAZN | 0.57947 | 5 | 0 | 4 |
| GMEB1 | B3GNT3 | 0.578103 | 6 | 0 | 4 |
| GMEB1 | RTKN2 | 0.57784 | 4 | 0 | 3 |
For details and further investigation, click here
