| Full name: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 | Alias Symbol: B3GN-T3|beta3Gn-T3|HP10328|B3GNT-3 | ||
| Type: protein-coding gene | Cytoband: 19p13.11 | ||
| Entrez ID: 10331 | HGNC ID: HGNC:13528 | Ensembl Gene: ENSG00000179913 | OMIM ID: 605863 |
| Drug and gene relationship at DGIdb | |||
Expression of B3GNT3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | B3GNT3 | 10331 | 204856_at | -0.2153 | 0.7625 | |
| GSE20347 | B3GNT3 | 10331 | 204856_at | -0.6532 | 0.0000 | |
| GSE23400 | B3GNT3 | 10331 | 204856_at | -0.6371 | 0.0000 | |
| GSE26886 | B3GNT3 | 10331 | 204856_at | -1.1939 | 0.0000 | |
| GSE29001 | B3GNT3 | 10331 | 204856_at | -0.7120 | 0.0276 | |
| GSE38129 | B3GNT3 | 10331 | 204856_at | -0.6157 | 0.0003 | |
| GSE45670 | B3GNT3 | 10331 | 204856_at | -0.2560 | 0.3256 | |
| GSE53622 | B3GNT3 | 10331 | 121125 | -1.0247 | 0.0000 | |
| GSE53624 | B3GNT3 | 10331 | 121125 | -1.6649 | 0.0000 | |
| GSE63941 | B3GNT3 | 10331 | 204856_at | 1.4429 | 0.0425 | |
| GSE77861 | B3GNT3 | 10331 | 204856_at | -0.6057 | 0.0122 | |
| GSE97050 | B3GNT3 | 10331 | A_23_P78980 | 0.1677 | 0.8232 | |
| SRP007169 | B3GNT3 | 10331 | RNAseq | -3.1521 | 0.0001 | |
| SRP008496 | B3GNT3 | 10331 | RNAseq | -4.2096 | 0.0000 | |
| SRP064894 | B3GNT3 | 10331 | RNAseq | -3.5458 | 0.0000 | |
| SRP133303 | B3GNT3 | 10331 | RNAseq | -1.6681 | 0.0003 | |
| SRP159526 | B3GNT3 | 10331 | RNAseq | -3.5310 | 0.0000 | |
| SRP193095 | B3GNT3 | 10331 | RNAseq | -1.9839 | 0.0000 | |
| SRP219564 | B3GNT3 | 10331 | RNAseq | -2.3207 | 0.0321 | |
| TCGA | B3GNT3 | 10331 | RNAseq | -0.8557 | 0.0014 |
Upregulated datasets: 1; Downregulated datasets: 10.
Survival by B3GNT3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of B3GNT3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | B3GNT3 | 10331 | 4 | 4 | 22 | |
| GSE20123 | B3GNT3 | 10331 | 3 | 2 | 25 | |
| GSE43470 | B3GNT3 | 10331 | 2 | 6 | 35 | |
| GSE46452 | B3GNT3 | 10331 | 47 | 1 | 11 | |
| GSE47630 | B3GNT3 | 10331 | 4 | 8 | 28 | |
| GSE54993 | B3GNT3 | 10331 | 15 | 4 | 51 | |
| GSE54994 | B3GNT3 | 10331 | 6 | 14 | 33 | |
| GSE60625 | B3GNT3 | 10331 | 9 | 0 | 2 | |
| GSE74703 | B3GNT3 | 10331 | 2 | 4 | 30 | |
| GSE74704 | B3GNT3 | 10331 | 0 | 2 | 18 | |
| TCGA | B3GNT3 | 10331 | 17 | 9 | 70 |
Total number of gains: 109; Total number of losses: 54; Total Number of normals: 325.
Somatic mutations of B3GNT3:
Generating mutation plots.
Highly correlated genes for B3GNT3:
Showing top 20/925 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| B3GNT3 | ARHGAP40 | 0.754556 | 3 | 0 | 3 |
| B3GNT3 | ANXA9 | 0.749272 | 10 | 0 | 10 |
| B3GNT3 | PRSS2 | 0.7263 | 8 | 0 | 8 |
| B3GNT3 | EPS8L1 | 0.725951 | 12 | 0 | 12 |
| B3GNT3 | PRSS3 | 0.719788 | 10 | 0 | 10 |
| B3GNT3 | SDCBP2 | 0.71963 | 3 | 0 | 3 |
| B3GNT3 | CYSRT1 | 0.7122 | 6 | 0 | 6 |
| B3GNT3 | MAPK3 | 0.710534 | 9 | 0 | 9 |
| B3GNT3 | NCCRP1 | 0.708771 | 3 | 0 | 3 |
| B3GNT3 | TTC22 | 0.708401 | 12 | 0 | 11 |
| B3GNT3 | PSCA | 0.706841 | 8 | 0 | 7 |
| B3GNT3 | PTK6 | 0.706663 | 11 | 0 | 11 |
| B3GNT3 | MACC1 | 0.702972 | 8 | 0 | 8 |
| B3GNT3 | GDPD3 | 0.70007 | 11 | 0 | 11 |
| B3GNT3 | SLC37A1 | 0.69971 | 12 | 0 | 12 |
| B3GNT3 | EPS8L2 | 0.698551 | 12 | 0 | 10 |
| B3GNT3 | VSIG2 | 0.698309 | 8 | 0 | 8 |
| B3GNT3 | TJP3 | 0.698217 | 12 | 0 | 12 |
| B3GNT3 | CYP3A7 | 0.698039 | 3 | 0 | 3 |
| B3GNT3 | RDH12 | 0.697688 | 4 | 0 | 4 |
For details and further investigation, click here
