| Full name: kazrin, periplakin interacting protein | Alias Symbol: KIAA1026|KAZRIN|FLJ43806 | ||
| Type: protein-coding gene | Cytoband: 1p36.21 | ||
| Entrez ID: 23254 | HGNC ID: HGNC:29173 | Ensembl Gene: ENSG00000189337 | OMIM ID: 618301 |
| Drug and gene relationship at DGIdb | |||
Expression of KAZN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KAZN | 23254 | 213478_at | -0.1963 | 0.8362 | |
| GSE20347 | KAZN | 23254 | 213478_at | -0.8934 | 0.0003 | |
| GSE23400 | KAZN | 23254 | 213478_at | -0.8471 | 0.0000 | |
| GSE26886 | KAZN | 23254 | 213478_at | -1.7937 | 0.0000 | |
| GSE29001 | KAZN | 23254 | 213478_at | -0.8554 | 0.0141 | |
| GSE38129 | KAZN | 23254 | 213478_at | -0.4575 | 0.2463 | |
| GSE45670 | KAZN | 23254 | 213478_at | -0.4106 | 0.1882 | |
| GSE53622 | KAZN | 23254 | 50038 | -1.2097 | 0.0000 | |
| GSE53624 | KAZN | 23254 | 50038 | -1.8127 | 0.0000 | |
| GSE63941 | KAZN | 23254 | 213478_at | 0.1367 | 0.8812 | |
| GSE77861 | KAZN | 23254 | 213478_at | -0.9138 | 0.0107 | |
| GSE97050 | KAZN | 23254 | A_24_P331830 | -0.5058 | 0.2982 | |
| SRP007169 | KAZN | 23254 | RNAseq | -3.2948 | 0.0000 | |
| SRP008496 | KAZN | 23254 | RNAseq | -3.2731 | 0.0000 | |
| SRP064894 | KAZN | 23254 | RNAseq | -2.1172 | 0.0000 | |
| SRP133303 | KAZN | 23254 | RNAseq | -1.5368 | 0.0000 | |
| SRP159526 | KAZN | 23254 | RNAseq | -1.6754 | 0.0000 | |
| SRP193095 | KAZN | 23254 | RNAseq | -1.4314 | 0.0000 | |
| SRP219564 | KAZN | 23254 | RNAseq | -1.5816 | 0.0205 |
Upregulated datasets: 0; Downregulated datasets: 10.
Survival by KAZN expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of KAZN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KAZN | 23254 | 0 | 4 | 26 | |
| GSE20123 | KAZN | 23254 | 0 | 3 | 27 | |
| GSE43470 | KAZN | 23254 | 1 | 8 | 34 | |
| GSE46452 | KAZN | 23254 | 7 | 1 | 51 | |
| GSE47630 | KAZN | 23254 | 8 | 3 | 29 | |
| GSE54993 | KAZN | 23254 | 3 | 1 | 66 | |
| GSE54994 | KAZN | 23254 | 10 | 4 | 39 | |
| GSE60625 | KAZN | 23254 | 0 | 0 | 11 | |
| GSE74703 | KAZN | 23254 | 1 | 5 | 30 | |
| GSE74704 | KAZN | 23254 | 0 | 0 | 20 | |
| TCGA | KAZN | 23254 | 11 | 24 | 61 |
Total number of gains: 41; Total number of losses: 53; Total Number of normals: 394.
Somatic mutations of KAZN:
Generating mutation plots.
Highly correlated genes for KAZN:
Showing top 20/1496 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KAZN | UPK3B | 0.856411 | 3 | 0 | 3 |
| KAZN | EPGN | 0.845208 | 3 | 0 | 3 |
| KAZN | NIPAL1 | 0.804493 | 3 | 0 | 3 |
| KAZN | FAM95B1 | 0.791445 | 3 | 0 | 3 |
| KAZN | ULK3 | 0.786801 | 7 | 0 | 7 |
| KAZN | NCCRP1 | 0.784813 | 3 | 0 | 3 |
| KAZN | EXPH5 | 0.776612 | 11 | 0 | 11 |
| KAZN | GIPC1 | 0.77652 | 10 | 0 | 10 |
| KAZN | ZNRF1 | 0.775846 | 5 | 0 | 5 |
| KAZN | EPS8L1 | 0.773302 | 11 | 0 | 11 |
| KAZN | CAPNS2 | 0.766923 | 3 | 0 | 3 |
| KAZN | ATG9B | 0.765997 | 7 | 0 | 7 |
| KAZN | FAM3D | 0.76514 | 7 | 0 | 7 |
| KAZN | TMEM79 | 0.764605 | 6 | 0 | 6 |
| KAZN | NUAK2 | 0.764197 | 3 | 0 | 3 |
| KAZN | TTC9 | 0.76366 | 11 | 0 | 11 |
| KAZN | C5orf66-AS1 | 0.763182 | 6 | 0 | 5 |
| KAZN | FUT3 | 0.762835 | 11 | 0 | 11 |
| KAZN | EVPL | 0.762335 | 11 | 0 | 11 |
| KAZN | MPZL3 | 0.759292 | 7 | 0 | 7 |
For details and further investigation, click here
