| Full name: mbt domain containing 1 | Alias Symbol: SA49P01|FLJ20055 | ||
| Type: protein-coding gene | Cytoband: 17q21.33 | ||
| Entrez ID: 54799 | HGNC ID: HGNC:19866 | Ensembl Gene: ENSG00000011258 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of MBTD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MBTD1 | 54799 | 226797_at | 0.1538 | 0.7492 | |
| GSE20347 | MBTD1 | 54799 | 207115_x_at | 0.1198 | 0.4973 | |
| GSE23400 | MBTD1 | 54799 | 207115_x_at | 0.0449 | 0.2283 | |
| GSE26886 | MBTD1 | 54799 | 226797_at | -0.7070 | 0.0568 | |
| GSE29001 | MBTD1 | 54799 | 207115_x_at | 0.1500 | 0.3145 | |
| GSE38129 | MBTD1 | 54799 | 207115_x_at | 0.1358 | 0.4141 | |
| GSE45670 | MBTD1 | 54799 | 226797_at | -0.0874 | 0.6797 | |
| GSE53622 | MBTD1 | 54799 | 56496 | 0.0749 | 0.3415 | |
| GSE53624 | MBTD1 | 54799 | 56496 | 0.1163 | 0.0951 | |
| GSE63941 | MBTD1 | 54799 | 226797_at | 0.3878 | 0.5276 | |
| GSE77861 | MBTD1 | 54799 | 226797_at | -0.2437 | 0.4288 | |
| GSE97050 | MBTD1 | 54799 | A_33_P3233005 | 0.2406 | 0.3638 | |
| SRP007169 | MBTD1 | 54799 | RNAseq | -0.2784 | 0.4666 | |
| SRP008496 | MBTD1 | 54799 | RNAseq | -0.2733 | 0.1749 | |
| SRP064894 | MBTD1 | 54799 | RNAseq | -0.2842 | 0.2318 | |
| SRP133303 | MBTD1 | 54799 | RNAseq | -0.1112 | 0.3348 | |
| SRP159526 | MBTD1 | 54799 | RNAseq | -0.1426 | 0.5387 | |
| SRP193095 | MBTD1 | 54799 | RNAseq | -0.4224 | 0.0000 | |
| SRP219564 | MBTD1 | 54799 | RNAseq | -0.1776 | 0.7119 | |
| TCGA | MBTD1 | 54799 | RNAseq | -0.0840 | 0.1771 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MBTD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MBTD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MBTD1 | 54799 | 5 | 2 | 23 | |
| GSE20123 | MBTD1 | 54799 | 5 | 2 | 23 | |
| GSE43470 | MBTD1 | 54799 | 3 | 2 | 38 | |
| GSE46452 | MBTD1 | 54799 | 32 | 0 | 27 | |
| GSE47630 | MBTD1 | 54799 | 9 | 0 | 31 | |
| GSE54993 | MBTD1 | 54799 | 2 | 4 | 64 | |
| GSE54994 | MBTD1 | 54799 | 8 | 6 | 39 | |
| GSE60625 | MBTD1 | 54799 | 4 | 0 | 7 | |
| GSE74703 | MBTD1 | 54799 | 3 | 2 | 31 | |
| GSE74704 | MBTD1 | 54799 | 4 | 1 | 15 | |
| TCGA | MBTD1 | 54799 | 26 | 8 | 62 |
Total number of gains: 101; Total number of losses: 27; Total Number of normals: 360.
Somatic mutations of MBTD1:
Generating mutation plots.
Highly correlated genes for MBTD1:
Showing top 20/61 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MBTD1 | PGF | 0.689348 | 6 | 0 | 4 |
| MBTD1 | ZNF160 | 0.688774 | 6 | 0 | 5 |
| MBTD1 | GMEB1 | 0.688518 | 3 | 0 | 3 |
| MBTD1 | RAB11FIP4 | 0.682007 | 3 | 0 | 3 |
| MBTD1 | ZNF611 | 0.681208 | 5 | 0 | 4 |
| MBTD1 | CCNL2 | 0.679169 | 4 | 0 | 3 |
| MBTD1 | RANBP2 | 0.668787 | 4 | 0 | 3 |
| MBTD1 | HS6ST2 | 0.661403 | 3 | 0 | 3 |
| MBTD1 | PNMA3 | 0.660057 | 3 | 0 | 3 |
| MBTD1 | IL22RA2 | 0.65749 | 4 | 0 | 4 |
| MBTD1 | ZNF692 | 0.6491 | 4 | 0 | 4 |
| MBTD1 | GPR1 | 0.641148 | 5 | 0 | 3 |
| MBTD1 | CBX8 | 0.639227 | 3 | 0 | 3 |
| MBTD1 | ABCA7 | 0.625592 | 4 | 0 | 3 |
| MBTD1 | SERINC5 | 0.624299 | 4 | 0 | 3 |
| MBTD1 | NSUN6 | 0.623901 | 4 | 0 | 3 |
| MBTD1 | LARP4B | 0.62044 | 4 | 0 | 3 |
| MBTD1 | BROX | 0.61462 | 4 | 0 | 4 |
| MBTD1 | USP49 | 0.614094 | 8 | 0 | 7 |
| MBTD1 | PPIL2 | 0.611423 | 4 | 0 | 4 |
For details and further investigation, click here
