| Full name: solute carrier family 26 member 2 | Alias Symbol: DTDST | ||
| Type: protein-coding gene | Cytoband: 5q32 | ||
| Entrez ID: 1836 | HGNC ID: HGNC:10994 | Ensembl Gene: ENSG00000155850 | OMIM ID: 606718 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC26A2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC26A2 | 1836 | 224959_at | -0.8645 | 0.1769 | |
| GSE20347 | SLC26A2 | 1836 | 205097_at | -1.2924 | 0.0018 | |
| GSE23400 | SLC26A2 | 1836 | 205097_at | -0.8763 | 0.0000 | |
| GSE26886 | SLC26A2 | 1836 | 224959_at | -1.4402 | 0.0027 | |
| GSE29001 | SLC26A2 | 1836 | 205097_at | -1.0163 | 0.0550 | |
| GSE38129 | SLC26A2 | 1836 | 205097_at | -1.0157 | 0.0073 | |
| GSE45670 | SLC26A2 | 1836 | 224959_at | -1.3556 | 0.0000 | |
| GSE53622 | SLC26A2 | 1836 | 96346 | -1.1098 | 0.0000 | |
| GSE53624 | SLC26A2 | 1836 | 96346 | -1.2319 | 0.0000 | |
| GSE63941 | SLC26A2 | 1836 | 224959_at | -1.9692 | 0.0155 | |
| GSE77861 | SLC26A2 | 1836 | 224959_at | -1.6112 | 0.0051 | |
| GSE97050 | SLC26A2 | 1836 | A_33_P3277447 | -0.3850 | 0.4093 | |
| SRP007169 | SLC26A2 | 1836 | RNAseq | -2.0371 | 0.0001 | |
| SRP008496 | SLC26A2 | 1836 | RNAseq | -1.4791 | 0.0000 | |
| SRP064894 | SLC26A2 | 1836 | RNAseq | -1.3338 | 0.0000 | |
| SRP133303 | SLC26A2 | 1836 | RNAseq | -1.7846 | 0.0000 | |
| SRP159526 | SLC26A2 | 1836 | RNAseq | -0.1046 | 0.7868 | |
| SRP193095 | SLC26A2 | 1836 | RNAseq | -1.2185 | 0.0000 | |
| SRP219564 | SLC26A2 | 1836 | RNAseq | -0.7681 | 0.2310 | |
| TCGA | SLC26A2 | 1836 | RNAseq | 0.0082 | 0.9312 |
Upregulated datasets: 0; Downregulated datasets: 13.
Survival by SLC26A2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC26A2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC26A2 | 1836 | 1 | 12 | 17 | |
| GSE20123 | SLC26A2 | 1836 | 1 | 12 | 17 | |
| GSE43470 | SLC26A2 | 1836 | 1 | 10 | 32 | |
| GSE46452 | SLC26A2 | 1836 | 0 | 27 | 32 | |
| GSE47630 | SLC26A2 | 1836 | 0 | 20 | 20 | |
| GSE54993 | SLC26A2 | 1836 | 9 | 1 | 60 | |
| GSE54994 | SLC26A2 | 1836 | 2 | 15 | 36 | |
| GSE60625 | SLC26A2 | 1836 | 0 | 0 | 11 | |
| GSE74703 | SLC26A2 | 1836 | 1 | 7 | 28 | |
| GSE74704 | SLC26A2 | 1836 | 1 | 7 | 12 | |
| TCGA | SLC26A2 | 1836 | 5 | 38 | 53 |
Total number of gains: 21; Total number of losses: 149; Total Number of normals: 318.
Somatic mutations of SLC26A2:
Generating mutation plots.
Highly correlated genes for SLC26A2:
Showing top 20/501 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC26A2 | SH2D1B | 0.703581 | 4 | 0 | 4 |
| SLC26A2 | SMDT1 | 0.702443 | 4 | 0 | 4 |
| SLC26A2 | SAMD5 | 0.693002 | 6 | 0 | 6 |
| SLC26A2 | SH3BGRL2 | 0.684512 | 6 | 0 | 6 |
| SLC26A2 | MORN3 | 0.682363 | 4 | 0 | 4 |
| SLC26A2 | SPINK7 | 0.678805 | 7 | 0 | 7 |
| SLC26A2 | ALDH9A1 | 0.675621 | 11 | 0 | 11 |
| SLC26A2 | CAPN14 | 0.674755 | 6 | 0 | 6 |
| SLC26A2 | CTTNBP2 | 0.670544 | 8 | 0 | 8 |
| SLC26A2 | SUCLA2 | 0.669962 | 3 | 0 | 3 |
| SLC26A2 | VSIG10L | 0.668648 | 7 | 0 | 7 |
| SLC26A2 | SMIM15 | 0.666128 | 3 | 0 | 3 |
| SLC26A2 | PAQR8 | 0.664764 | 6 | 0 | 6 |
| SLC26A2 | SNORA68 | 0.664683 | 4 | 0 | 4 |
| SLC26A2 | RAET1E | 0.663525 | 7 | 0 | 7 |
| SLC26A2 | FAM163B | 0.660409 | 3 | 0 | 3 |
| SLC26A2 | AP4B1 | 0.660155 | 7 | 0 | 6 |
| SLC26A2 | FAM221A | 0.658852 | 5 | 0 | 5 |
| SLC26A2 | FAM214A | 0.656134 | 6 | 0 | 6 |
| SLC26A2 | KRTAP20-1 | 0.654664 | 3 | 0 | 3 |
For details and further investigation, click here
