| Full name: capping actin protein, gelsolin like | Alias Symbol: MCP | ||
| Type: protein-coding gene | Cytoband: 2p11.2 | ||
| Entrez ID: 822 | HGNC ID: HGNC:1474 | Ensembl Gene: ENSG00000042493 | OMIM ID: 153615 |
| Drug and gene relationship at DGIdb | |||
Expression of CAPG:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CAPG | 822 | 201850_at | 0.0207 | 0.9846 | |
| GSE20347 | CAPG | 822 | 201850_at | -1.0554 | 0.0000 | |
| GSE23400 | CAPG | 822 | 201850_at | -0.1904 | 0.1404 | |
| GSE26886 | CAPG | 822 | 201850_at | -1.1713 | 0.0001 | |
| GSE29001 | CAPG | 822 | 201850_at | -0.6803 | 0.0158 | |
| GSE38129 | CAPG | 822 | 201850_at | -0.1813 | 0.5704 | |
| GSE45670 | CAPG | 822 | 201850_at | 0.0401 | 0.8529 | |
| GSE53622 | CAPG | 822 | 24070 | 0.1638 | 0.3456 | |
| GSE53624 | CAPG | 822 | 38586 | -0.5472 | 0.0000 | |
| GSE63941 | CAPG | 822 | 201850_at | 1.5939 | 0.0338 | |
| GSE77861 | CAPG | 822 | 201850_at | -0.6279 | 0.0666 | |
| GSE97050 | CAPG | 822 | A_33_P3305758 | 0.3872 | 0.4806 | |
| SRP007169 | CAPG | 822 | RNAseq | -1.2331 | 0.0084 | |
| SRP008496 | CAPG | 822 | RNAseq | -1.2616 | 0.0000 | |
| SRP064894 | CAPG | 822 | RNAseq | 0.3623 | 0.2563 | |
| SRP133303 | CAPG | 822 | RNAseq | -0.0042 | 0.9841 | |
| SRP159526 | CAPG | 822 | RNAseq | -1.0057 | 0.0058 | |
| SRP193095 | CAPG | 822 | RNAseq | -0.7237 | 0.0000 | |
| SRP219564 | CAPG | 822 | RNAseq | 0.2394 | 0.7456 | |
| TCGA | CAPG | 822 | RNAseq | 0.3528 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 5.
Survival by CAPG expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CAPG:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CAPG | 822 | 9 | 2 | 19 | |
| GSE20123 | CAPG | 822 | 9 | 2 | 19 | |
| GSE43470 | CAPG | 822 | 6 | 2 | 35 | |
| GSE46452 | CAPG | 822 | 2 | 3 | 54 | |
| GSE47630 | CAPG | 822 | 7 | 0 | 33 | |
| GSE54993 | CAPG | 822 | 0 | 6 | 64 | |
| GSE54994 | CAPG | 822 | 10 | 0 | 43 | |
| GSE60625 | CAPG | 822 | 0 | 3 | 8 | |
| GSE74703 | CAPG | 822 | 5 | 1 | 30 | |
| GSE74704 | CAPG | 822 | 7 | 0 | 13 | |
| TCGA | CAPG | 822 | 35 | 3 | 58 |
Total number of gains: 90; Total number of losses: 22; Total Number of normals: 376.
Somatic mutations of CAPG:
Generating mutation plots.
Highly correlated genes for CAPG:
Showing top 20/589 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CAPG | FAM83G | 0.789775 | 3 | 0 | 3 |
| CAPG | VDR | 0.733341 | 8 | 0 | 7 |
| CAPG | TMED3 | 0.698033 | 10 | 0 | 10 |
| CAPG | PDCD6IP | 0.688279 | 7 | 0 | 7 |
| CAPG | RIPK3 | 0.679683 | 5 | 0 | 5 |
| CAPG | HIPK2 | 0.677884 | 3 | 0 | 3 |
| CAPG | TRIM29 | 0.668516 | 10 | 0 | 8 |
| CAPG | ANXA2 | 0.657738 | 11 | 0 | 9 |
| CAPG | ELMO3 | 0.655769 | 6 | 0 | 5 |
| CAPG | ELOVL1 | 0.652658 | 3 | 0 | 3 |
| CAPG | PRSS8 | 0.651994 | 9 | 0 | 8 |
| CAPG | PTBP3 | 0.651899 | 5 | 0 | 4 |
| CAPG | PRSS16 | 0.649905 | 6 | 0 | 4 |
| CAPG | PKP3 | 0.649153 | 11 | 0 | 9 |
| CAPG | LYPD3 | 0.645831 | 11 | 0 | 9 |
| CAPG | OSBPL3 | 0.645075 | 3 | 0 | 3 |
| CAPG | GJB5 | 0.642463 | 13 | 0 | 10 |
| CAPG | ZNF385A | 0.642363 | 4 | 0 | 4 |
| CAPG | ASL | 0.640887 | 6 | 0 | 6 |
| CAPG | PRRG4 | 0.638766 | 9 | 0 | 8 |
For details and further investigation, click here
