| Full name: ectonucleoside triphosphate diphosphohydrolase 5 (inactive) | Alias Symbol: NTPDase-5 | ||
| Type: protein-coding gene | Cytoband: 14q24.3 | ||
| Entrez ID: 957 | HGNC ID: HGNC:3367 | Ensembl Gene: ENSG00000187097 | OMIM ID: 603162 |
| Drug and gene relationship at DGIdb | |||
Expression of ENTPD5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ENTPD5 | 957 | 226594_at | -0.7016 | 0.2279 | |
| GSE20347 | ENTPD5 | 957 | 205757_at | -0.8814 | 0.0000 | |
| GSE23400 | ENTPD5 | 957 | 205757_at | -0.2007 | 0.0000 | |
| GSE26886 | ENTPD5 | 957 | 226594_at | -1.4921 | 0.0000 | |
| GSE29001 | ENTPD5 | 957 | 205757_at | -0.5456 | 0.0992 | |
| GSE38129 | ENTPD5 | 957 | 205757_at | -0.6960 | 0.0017 | |
| GSE45670 | ENTPD5 | 957 | 226594_at | -0.7008 | 0.0000 | |
| GSE53622 | ENTPD5 | 957 | 120146 | -0.8391 | 0.0000 | |
| GSE53624 | ENTPD5 | 957 | 120146 | -0.7176 | 0.0000 | |
| GSE63941 | ENTPD5 | 957 | 226594_at | -0.5518 | 0.0856 | |
| GSE77861 | ENTPD5 | 957 | 226594_at | -1.2167 | 0.0009 | |
| GSE97050 | ENTPD5 | 957 | A_23_P117580 | 0.1059 | 0.6146 | |
| SRP007169 | ENTPD5 | 957 | RNAseq | -1.7374 | 0.0000 | |
| SRP008496 | ENTPD5 | 957 | RNAseq | -1.6079 | 0.0000 | |
| SRP064894 | ENTPD5 | 957 | RNAseq | -0.4259 | 0.0722 | |
| SRP133303 | ENTPD5 | 957 | RNAseq | -0.4434 | 0.0002 | |
| SRP159526 | ENTPD5 | 957 | RNAseq | -0.7669 | 0.0099 | |
| SRP193095 | ENTPD5 | 957 | RNAseq | -1.3331 | 0.0000 | |
| SRP219564 | ENTPD5 | 957 | RNAseq | -0.3107 | 0.4708 | |
| TCGA | ENTPD5 | 957 | RNAseq | -0.3025 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by ENTPD5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ENTPD5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ENTPD5 | 957 | 8 | 2 | 20 | |
| GSE20123 | ENTPD5 | 957 | 8 | 2 | 20 | |
| GSE43470 | ENTPD5 | 957 | 8 | 3 | 32 | |
| GSE46452 | ENTPD5 | 957 | 16 | 3 | 40 | |
| GSE47630 | ENTPD5 | 957 | 11 | 8 | 21 | |
| GSE54993 | ENTPD5 | 957 | 3 | 8 | 59 | |
| GSE54994 | ENTPD5 | 957 | 19 | 4 | 30 | |
| GSE60625 | ENTPD5 | 957 | 0 | 2 | 9 | |
| GSE74703 | ENTPD5 | 957 | 7 | 3 | 26 | |
| GSE74704 | ENTPD5 | 957 | 3 | 2 | 15 | |
| TCGA | ENTPD5 | 957 | 32 | 16 | 48 |
Total number of gains: 115; Total number of losses: 53; Total Number of normals: 320.
Somatic mutations of ENTPD5:
Generating mutation plots.
Highly correlated genes for ENTPD5:
Showing top 20/648 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ENTPD5 | NICN1 | 0.806183 | 3 | 0 | 3 |
| ENTPD5 | DEGS2 | 0.784342 | 7 | 0 | 7 |
| ENTPD5 | ZNF780A | 0.773818 | 3 | 0 | 3 |
| ENTPD5 | KRT74 | 0.758321 | 3 | 0 | 3 |
| ENTPD5 | RAET1E | 0.756024 | 7 | 0 | 7 |
| ENTPD5 | KRT78 | 0.750937 | 6 | 0 | 6 |
| ENTPD5 | KCNT1 | 0.74913 | 3 | 0 | 3 |
| ENTPD5 | ZNRF1 | 0.745104 | 4 | 0 | 4 |
| ENTPD5 | TCP11L2 | 0.741068 | 4 | 0 | 4 |
| ENTPD5 | SLC35C1 | 0.740298 | 11 | 0 | 11 |
| ENTPD5 | AP4B1 | 0.738679 | 6 | 0 | 6 |
| ENTPD5 | FAM163B | 0.737129 | 3 | 0 | 3 |
| ENTPD5 | EPS8L2 | 0.731407 | 12 | 0 | 11 |
| ENTPD5 | ACER1 | 0.730106 | 7 | 0 | 7 |
| ENTPD5 | A2ML1 | 0.727771 | 6 | 0 | 6 |
| ENTPD5 | C6orf132 | 0.725889 | 7 | 0 | 7 |
| ENTPD5 | ESPL1 | 0.723766 | 11 | 0 | 11 |
| ENTPD5 | HECTD1 | 0.721442 | 6 | 0 | 6 |
| ENTPD5 | OR10G8 | 0.721323 | 3 | 0 | 3 |
| ENTPD5 | TTC9 | 0.719351 | 10 | 0 | 9 |
For details and further investigation, click here
