| Full name: geminin coiled-coil domain containing | Alias Symbol: GEMC1 | ||
| Type: protein-coding gene | Cytoband: 3q28 | ||
| Entrez ID: 647309 | HGNC ID: HGNC:40049 | Ensembl Gene: ENSG00000205835 | OMIM ID: 614448 |
| Drug and gene relationship at DGIdb | |||
Expression of GMNC:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GMNC | 647309 | 1569616_at | 0.0572 | 0.8648 | |
| GSE26886 | GMNC | 647309 | 1569616_at | 0.0132 | 0.9160 | |
| GSE45670 | GMNC | 647309 | 1569616_at | -0.0182 | 0.8497 | |
| GSE53622 | GMNC | 647309 | 123038 | 0.1171 | 0.5542 | |
| GSE53624 | GMNC | 647309 | 123038 | 0.2198 | 0.0266 | |
| GSE63941 | GMNC | 647309 | 1569616_at | 0.0558 | 0.7448 | |
| GSE77861 | GMNC | 647309 | 1569616_at | -0.1675 | 0.2828 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GMNC expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of GMNC:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GMNC | 647309 | 25 | 0 | 5 | |
| GSE20123 | GMNC | 647309 | 25 | 0 | 5 | |
| GSE43470 | GMNC | 647309 | 27 | 0 | 16 | |
| GSE46452 | GMNC | 647309 | 19 | 1 | 39 | |
| GSE47630 | GMNC | 647309 | 27 | 2 | 11 | |
| GSE54993 | GMNC | 647309 | 1 | 19 | 50 | |
| GSE54994 | GMNC | 647309 | 40 | 0 | 13 | |
| GSE60625 | GMNC | 647309 | 0 | 6 | 5 | |
| GSE74703 | GMNC | 647309 | 21 | 0 | 15 | |
| GSE74704 | GMNC | 647309 | 17 | 0 | 3 | |
| TCGA | GMNC | 647309 | 76 | 0 | 20 |
Total number of gains: 278; Total number of losses: 28; Total Number of normals: 182.
Somatic mutations of GMNC:
Generating mutation plots.
Highly correlated genes for GMNC:
Showing all 17 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GMNC | PIGQ | 0.686505 | 3 | 0 | 3 |
| GMNC | STKLD1 | 0.626783 | 3 | 0 | 3 |
| GMNC | TSACC | 0.617565 | 4 | 0 | 3 |
| GMNC | MOGAT2 | 0.615111 | 3 | 0 | 3 |
| GMNC | SORCS3-AS1 | 0.609492 | 3 | 0 | 3 |
| GMNC | RABEP2 | 0.594797 | 3 | 0 | 3 |
| GMNC | KLC4 | 0.592683 | 4 | 0 | 3 |
| GMNC | NAT2 | 0.590147 | 3 | 0 | 3 |
| GMNC | SCN10A | 0.580907 | 3 | 0 | 3 |
| GMNC | ASB12 | 0.566344 | 4 | 0 | 3 |
| GMNC | KLF14 | 0.559632 | 4 | 0 | 3 |
| GMNC | TEX36 | 0.557028 | 3 | 0 | 3 |
| GMNC | HAND1 | 0.551284 | 3 | 0 | 3 |
| GMNC | CD3E | 0.533075 | 3 | 0 | 3 |
| GMNC | ASCL3 | 0.531545 | 3 | 0 | 3 |
| GMNC | HPX | 0.522145 | 3 | 0 | 3 |
| GMNC | LINC00671 | 0.521793 | 4 | 0 | 3 |
For details and further investigation, click here
