| Full name: Kruppel like factor 14 | Alias Symbol: BTEB5 | ||
| Type: protein-coding gene | Cytoband: 7q32.2 | ||
| Entrez ID: 136259 | HGNC ID: HGNC:23025 | Ensembl Gene: ENSG00000266265 | OMIM ID: 609393 |
| Drug and gene relationship at DGIdb | |||
Expression of KLF14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KLF14 | 136259 | 1552813_at | -0.0281 | 0.9655 | |
| GSE26886 | KLF14 | 136259 | 1552813_at | -0.3127 | 0.0480 | |
| GSE45670 | KLF14 | 136259 | 1552813_at | 0.0190 | 0.9024 | |
| GSE53622 | KLF14 | 136259 | 6778 | 0.4836 | 0.0000 | |
| GSE53624 | KLF14 | 136259 | 6778 | 0.4335 | 0.0000 | |
| GSE63941 | KLF14 | 136259 | 1552813_at | 0.3103 | 0.2749 | |
| GSE77861 | KLF14 | 136259 | 1552813_at | -0.3413 | 0.1055 | |
| GSE97050 | KLF14 | 136259 | A_33_P3374947 | 0.0703 | 0.7646 | |
| TCGA | KLF14 | 136259 | RNAseq | 2.4933 | 0.0001 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by KLF14 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KLF14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KLF14 | 136259 | 8 | 1 | 21 | |
| GSE20123 | KLF14 | 136259 | 8 | 1 | 21 | |
| GSE43470 | KLF14 | 136259 | 2 | 3 | 38 | |
| GSE46452 | KLF14 | 136259 | 7 | 2 | 50 | |
| GSE47630 | KLF14 | 136259 | 7 | 4 | 29 | |
| GSE54993 | KLF14 | 136259 | 3 | 5 | 62 | |
| GSE54994 | KLF14 | 136259 | 7 | 7 | 39 | |
| GSE60625 | KLF14 | 136259 | 0 | 0 | 11 | |
| GSE74703 | KLF14 | 136259 | 2 | 3 | 31 | |
| GSE74704 | KLF14 | 136259 | 4 | 1 | 15 | |
| TCGA | KLF14 | 136259 | 27 | 22 | 47 |
Total number of gains: 75; Total number of losses: 49; Total Number of normals: 364.
Somatic mutations of KLF14:
Generating mutation plots.
Highly correlated genes for KLF14:
Showing top 20/224 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KLF14 | ALG11 | 0.774629 | 3 | 0 | 3 |
| KLF14 | OBP2A | 0.762998 | 3 | 0 | 3 |
| KLF14 | ZNF248 | 0.762464 | 3 | 0 | 3 |
| KLF14 | SLC26A5 | 0.747018 | 3 | 0 | 3 |
| KLF14 | FAM111B | 0.74254 | 3 | 0 | 3 |
| KLF14 | OR2AT4 | 0.738173 | 3 | 0 | 3 |
| KLF14 | DMWD | 0.731384 | 4 | 0 | 4 |
| KLF14 | ATP1A4 | 0.729709 | 3 | 0 | 3 |
| KLF14 | NFAM1 | 0.726205 | 3 | 0 | 3 |
| KLF14 | ITIH6 | 0.725484 | 4 | 0 | 4 |
| KLF14 | E2F4 | 0.714375 | 5 | 0 | 4 |
| KLF14 | OR2T33 | 0.712153 | 3 | 0 | 3 |
| KLF14 | TIMM23 | 0.71188 | 4 | 0 | 3 |
| KLF14 | OR1L6 | 0.70998 | 3 | 0 | 3 |
| KLF14 | TAS2R43 | 0.707086 | 3 | 0 | 3 |
| KLF14 | PRR23C | 0.700726 | 3 | 0 | 3 |
| KLF14 | ASB3 | 0.700614 | 3 | 0 | 3 |
| KLF14 | AKIRIN2 | 0.685591 | 3 | 0 | 3 |
| KLF14 | CST6 | 0.685475 | 3 | 0 | 3 |
| KLF14 | MAS1 | 0.684229 | 4 | 0 | 4 |
For details and further investigation, click here
