| Full name: guanosine monophosphate reductase 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 14q12 | ||
| Entrez ID: 51292 | HGNC ID: HGNC:4377 | Ensembl Gene: ENSG00000100938 | OMIM ID: 610781 |
| Drug and gene relationship at DGIdb | |||
Expression of GMPR2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GMPR2 | 51292 | 217990_at | -0.0384 | 0.9702 | |
| GSE20347 | GMPR2 | 51292 | 217990_at | 0.3401 | 0.1305 | |
| GSE23400 | GMPR2 | 51292 | 217990_at | 0.5120 | 0.0000 | |
| GSE26886 | GMPR2 | 51292 | 217990_at | -0.4550 | 0.1501 | |
| GSE29001 | GMPR2 | 51292 | 217990_at | 0.6742 | 0.0477 | |
| GSE38129 | GMPR2 | 51292 | 217990_at | 0.2461 | 0.1089 | |
| GSE45670 | GMPR2 | 51292 | 217990_at | 0.0950 | 0.6654 | |
| GSE53622 | GMPR2 | 51292 | 112017 | 0.1416 | 0.0671 | |
| GSE53624 | GMPR2 | 51292 | 112017 | 0.2546 | 0.0000 | |
| GSE63941 | GMPR2 | 51292 | 217990_at | 0.6310 | 0.3546 | |
| GSE77861 | GMPR2 | 51292 | 217990_at | 0.3849 | 0.3353 | |
| GSE97050 | GMPR2 | 51292 | A_24_P56467 | 0.1896 | 0.4271 | |
| SRP007169 | GMPR2 | 51292 | RNAseq | 0.1884 | 0.6284 | |
| SRP008496 | GMPR2 | 51292 | RNAseq | 0.2483 | 0.2826 | |
| SRP064894 | GMPR2 | 51292 | RNAseq | 0.3893 | 0.0078 | |
| SRP133303 | GMPR2 | 51292 | RNAseq | 0.1374 | 0.5598 | |
| SRP159526 | GMPR2 | 51292 | RNAseq | -0.0215 | 0.9351 | |
| SRP193095 | GMPR2 | 51292 | RNAseq | -0.0359 | 0.7807 | |
| SRP219564 | GMPR2 | 51292 | RNAseq | 0.1265 | 0.6197 | |
| TCGA | GMPR2 | 51292 | RNAseq | -0.0423 | 0.4099 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GMPR2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GMPR2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GMPR2 | 51292 | 8 | 3 | 19 | |
| GSE20123 | GMPR2 | 51292 | 8 | 3 | 19 | |
| GSE43470 | GMPR2 | 51292 | 8 | 2 | 33 | |
| GSE46452 | GMPR2 | 51292 | 16 | 2 | 41 | |
| GSE47630 | GMPR2 | 51292 | 11 | 10 | 19 | |
| GSE54993 | GMPR2 | 51292 | 3 | 11 | 56 | |
| GSE54994 | GMPR2 | 51292 | 18 | 5 | 30 | |
| GSE60625 | GMPR2 | 51292 | 0 | 2 | 9 | |
| GSE74703 | GMPR2 | 51292 | 7 | 2 | 27 | |
| GSE74704 | GMPR2 | 51292 | 3 | 2 | 15 | |
| TCGA | GMPR2 | 51292 | 27 | 13 | 56 |
Total number of gains: 109; Total number of losses: 55; Total Number of normals: 324.
Somatic mutations of GMPR2:
Generating mutation plots.
Highly correlated genes for GMPR2:
Showing top 20/432 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GMPR2 | RTN3 | 0.766696 | 4 | 0 | 4 |
| GMPR2 | OCIAD1 | 0.762078 | 3 | 0 | 3 |
| GMPR2 | C14orf119 | 0.758399 | 4 | 0 | 4 |
| GMPR2 | XRCC5 | 0.751793 | 3 | 0 | 3 |
| GMPR2 | NEDD8 | 0.737213 | 13 | 0 | 13 |
| GMPR2 | RLIM | 0.732595 | 3 | 0 | 3 |
| GMPR2 | USP37 | 0.727198 | 3 | 0 | 3 |
| GMPR2 | CETN3 | 0.714449 | 3 | 0 | 3 |
| GMPR2 | AKAP8 | 0.705152 | 4 | 0 | 3 |
| GMPR2 | KLF13 | 0.704045 | 3 | 0 | 3 |
| GMPR2 | CHURC1 | 0.700911 | 5 | 0 | 4 |
| GMPR2 | NAPG | 0.697677 | 4 | 0 | 4 |
| GMPR2 | FDPS | 0.69554 | 4 | 0 | 3 |
| GMPR2 | L3HYPDH | 0.690533 | 3 | 0 | 3 |
| GMPR2 | ZNF155 | 0.684149 | 3 | 0 | 3 |
| GMPR2 | RRS1 | 0.67978 | 3 | 0 | 3 |
| GMPR2 | KHNYN | 0.67819 | 7 | 0 | 6 |
| GMPR2 | SNX17 | 0.6777 | 4 | 0 | 3 |
| GMPR2 | PPP6R2 | 0.674469 | 3 | 0 | 3 |
| GMPR2 | NGDN | 0.674108 | 12 | 0 | 11 |
For details and further investigation, click here
