| Full name: ubiquitin specific peptidase 37 | Alias Symbol: KIAA1594 | ||
| Type: protein-coding gene | Cytoband: 2q35 | ||
| Entrez ID: 57695 | HGNC ID: HGNC:20063 | Ensembl Gene: ENSG00000135913 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of USP37:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | USP37 | 57695 | 226730_s_at | 0.4084 | 0.4544 | |
| GSE26886 | USP37 | 57695 | 226729_at | -0.4989 | 0.0038 | |
| GSE45670 | USP37 | 57695 | 232033_at | 0.4700 | 0.0079 | |
| GSE53622 | USP37 | 57695 | 163488 | 0.4772 | 0.0000 | |
| GSE53624 | USP37 | 57695 | 163488 | 0.3889 | 0.0000 | |
| GSE63941 | USP37 | 57695 | 226730_s_at | -0.0205 | 0.9553 | |
| GSE77861 | USP37 | 57695 | 226729_at | 0.3450 | 0.0762 | |
| GSE97050 | USP37 | 57695 | A_33_P3353425 | 0.2473 | 0.4484 | |
| SRP007169 | USP37 | 57695 | RNAseq | 0.8066 | 0.0584 | |
| SRP008496 | USP37 | 57695 | RNAseq | 0.6060 | 0.0274 | |
| SRP064894 | USP37 | 57695 | RNAseq | 0.1196 | 0.6540 | |
| SRP133303 | USP37 | 57695 | RNAseq | 0.5578 | 0.0001 | |
| SRP159526 | USP37 | 57695 | RNAseq | 0.3789 | 0.1660 | |
| SRP193095 | USP37 | 57695 | RNAseq | 0.2581 | 0.0275 | |
| SRP219564 | USP37 | 57695 | RNAseq | 0.1110 | 0.7876 | |
| TCGA | USP37 | 57695 | RNAseq | 0.0595 | 0.3502 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by USP37 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of USP37:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | USP37 | 57695 | 1 | 14 | 15 | |
| GSE20123 | USP37 | 57695 | 1 | 13 | 16 | |
| GSE43470 | USP37 | 57695 | 1 | 7 | 35 | |
| GSE46452 | USP37 | 57695 | 0 | 5 | 54 | |
| GSE47630 | USP37 | 57695 | 4 | 5 | 31 | |
| GSE54993 | USP37 | 57695 | 1 | 2 | 67 | |
| GSE54994 | USP37 | 57695 | 8 | 10 | 35 | |
| GSE60625 | USP37 | 57695 | 0 | 3 | 8 | |
| GSE74703 | USP37 | 57695 | 1 | 5 | 30 | |
| GSE74704 | USP37 | 57695 | 1 | 7 | 12 | |
| TCGA | USP37 | 57695 | 11 | 29 | 56 |
Total number of gains: 29; Total number of losses: 100; Total Number of normals: 359.
Somatic mutations of USP37:
Generating mutation plots.
Highly correlated genes for USP37:
Showing top 20/376 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| USP37 | PTGES3 | 0.799207 | 3 | 0 | 3 |
| USP37 | RNMT | 0.789919 | 3 | 0 | 3 |
| USP37 | PPP2R3C | 0.789743 | 3 | 0 | 3 |
| USP37 | TMEM205 | 0.786417 | 3 | 0 | 3 |
| USP37 | PWWP2A | 0.783679 | 3 | 0 | 3 |
| USP37 | PPIE | 0.774203 | 3 | 0 | 3 |
| USP37 | FAM102B | 0.774038 | 3 | 0 | 3 |
| USP37 | SLC38A1 | 0.771314 | 3 | 0 | 3 |
| USP37 | PIP4K2C | 0.768443 | 3 | 0 | 3 |
| USP37 | PSMC3 | 0.755051 | 3 | 0 | 3 |
| USP37 | FOXJ2 | 0.749787 | 3 | 0 | 3 |
| USP37 | PRPF38A | 0.748032 | 3 | 0 | 3 |
| USP37 | SRRM1 | 0.74803 | 3 | 0 | 3 |
| USP37 | MRPL37 | 0.746212 | 3 | 0 | 3 |
| USP37 | NBAS | 0.745652 | 3 | 0 | 3 |
| USP37 | KPNA6 | 0.744313 | 3 | 0 | 3 |
| USP37 | AGAP1 | 0.743533 | 3 | 0 | 3 |
| USP37 | ESYT1 | 0.74185 | 3 | 0 | 3 |
| USP37 | PRDX3 | 0.735044 | 3 | 0 | 3 |
| USP37 | GMPR2 | 0.727198 | 3 | 0 | 3 |
For details and further investigation, click here
