| Full name: centrin 3 | Alias Symbol: CEN3 | ||
| Type: protein-coding gene | Cytoband: 5q14.3 | ||
| Entrez ID: 1070 | HGNC ID: HGNC:1868 | Ensembl Gene: ENSG00000153140 | OMIM ID: 602907 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CETN3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CETN3 | 1070 | 209662_at | -0.5104 | 0.3897 | |
| GSE20347 | CETN3 | 1070 | 209662_at | -0.6134 | 0.0003 | |
| GSE23400 | CETN3 | 1070 | 209662_at | -0.0985 | 0.3148 | |
| GSE26886 | CETN3 | 1070 | 209662_at | -0.7334 | 0.0205 | |
| GSE29001 | CETN3 | 1070 | 209662_at | -0.1114 | 0.7507 | |
| GSE38129 | CETN3 | 1070 | 209662_at | -0.2012 | 0.1975 | |
| GSE45670 | CETN3 | 1070 | 209662_at | 0.0460 | 0.7886 | |
| GSE53622 | CETN3 | 1070 | 79324 | -0.2985 | 0.0000 | |
| GSE53624 | CETN3 | 1070 | 79324 | -0.4140 | 0.0000 | |
| GSE63941 | CETN3 | 1070 | 209662_at | 0.0631 | 0.8851 | |
| GSE77861 | CETN3 | 1070 | 209662_at | -0.7248 | 0.0023 | |
| GSE97050 | CETN3 | 1070 | A_23_P7732 | -0.4113 | 0.2317 | |
| SRP007169 | CETN3 | 1070 | RNAseq | -0.2515 | 0.6742 | |
| SRP008496 | CETN3 | 1070 | RNAseq | -0.6185 | 0.1490 | |
| SRP064894 | CETN3 | 1070 | RNAseq | -0.4524 | 0.0083 | |
| SRP133303 | CETN3 | 1070 | RNAseq | -0.0743 | 0.7607 | |
| SRP159526 | CETN3 | 1070 | RNAseq | -0.6280 | 0.0044 | |
| SRP193095 | CETN3 | 1070 | RNAseq | -1.2443 | 0.0000 | |
| SRP219564 | CETN3 | 1070 | RNAseq | -0.7640 | 0.0069 | |
| TCGA | CETN3 | 1070 | RNAseq | 0.1210 | 0.0862 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CETN3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CETN3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CETN3 | 1070 | 1 | 14 | 15 | |
| GSE20123 | CETN3 | 1070 | 1 | 14 | 15 | |
| GSE43470 | CETN3 | 1070 | 2 | 10 | 31 | |
| GSE46452 | CETN3 | 1070 | 0 | 28 | 31 | |
| GSE47630 | CETN3 | 1070 | 1 | 20 | 19 | |
| GSE54993 | CETN3 | 1070 | 8 | 1 | 61 | |
| GSE54994 | CETN3 | 1070 | 1 | 18 | 34 | |
| GSE60625 | CETN3 | 1070 | 0 | 0 | 11 | |
| GSE74703 | CETN3 | 1070 | 1 | 8 | 27 | |
| GSE74704 | CETN3 | 1070 | 1 | 7 | 12 | |
| TCGA | CETN3 | 1070 | 2 | 50 | 44 |
Total number of gains: 18; Total number of losses: 170; Total Number of normals: 300.
Somatic mutations of CETN3:
Generating mutation plots.
Highly correlated genes for CETN3:
Showing top 20/1041 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CETN3 | FBXL3 | 0.829168 | 3 | 0 | 3 |
| CETN3 | NUDT21 | 0.802185 | 3 | 0 | 3 |
| CETN3 | ATG12 | 0.785688 | 3 | 0 | 3 |
| CETN3 | DPH3 | 0.775773 | 3 | 0 | 3 |
| CETN3 | ZMPSTE24 | 0.775351 | 3 | 0 | 3 |
| CETN3 | HSPA9 | 0.771384 | 4 | 0 | 4 |
| CETN3 | SPTLC3 | 0.760659 | 4 | 0 | 3 |
| CETN3 | COG6 | 0.756939 | 4 | 0 | 4 |
| CETN3 | LRRC40 | 0.756148 | 3 | 0 | 3 |
| CETN3 | SLC25A43 | 0.746305 | 4 | 0 | 4 |
| CETN3 | IMPACT | 0.744481 | 4 | 0 | 4 |
| CETN3 | RBKS | 0.738903 | 4 | 0 | 4 |
| CETN3 | METAP2 | 0.73327 | 3 | 0 | 3 |
| CETN3 | SETMAR | 0.732436 | 4 | 0 | 3 |
| CETN3 | SLC22A15 | 0.731287 | 4 | 0 | 4 |
| CETN3 | COPS5 | 0.727609 | 3 | 0 | 3 |
| CETN3 | MTX2 | 0.726631 | 3 | 0 | 3 |
| CETN3 | FAM174A | 0.723413 | 6 | 0 | 4 |
| CETN3 | NDUFV2 | 0.722175 | 3 | 0 | 3 |
| CETN3 | KCNG2 | 0.722085 | 4 | 0 | 4 |
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