PPP6R2

 

Full name: protein phosphatase 6 regulatory subunit 2 Alias Symbol: dJ579N16.1|SAP190
Type: protein-coding gene Cytoband: 22q13.33
Entrez ID: 9701 HGNC ID: HGNC:19253 Ensembl Gene: ENSG00000100239 OMIM ID: 610877

 

Expression of PPP6R2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PPP6R2 9701 1570210_x_at 0.2416 0.7931
GSE20347 PPP6R2 9701 202791_s_at -0.2792 0.0026
GSE23400 PPP6R2 9701 202791_s_at -0.1552 0.0000
GSE26886 PPP6R2 9701 202791_s_at -0.1846 0.1820
GSE29001 PPP6R2 9701 202792_s_at -0.0403 0.8788
GSE38129 PPP6R2 9701 202791_s_at -0.2095 0.0023
GSE45670 PPP6R2 9701 1570210_x_at 0.3059 0.0170
GSE53622 PPP6R2 9701 64578 -0.1134 0.0867
GSE53624 PPP6R2 9701 64578 -0.0830 0.1432
GSE63941 PPP6R2 9701 202791_s_at 0.2492 0.6004
GSE77861 PPP6R2 9701 202791_s_at 0.0810 0.7016
GSE97050 PPP6R2 9701 A_33_P3396473 0.1009 0.6226
SRP007169 PPP6R2 9701 RNAseq -0.1970 0.5967
SRP008496 PPP6R2 9701 RNAseq -0.1614 0.4856
SRP064894 PPP6R2 9701 RNAseq 0.2037 0.2543
SRP133303 PPP6R2 9701 RNAseq -0.3267 0.0032
SRP159526 PPP6R2 9701 RNAseq -0.0273 0.8942
SRP193095 PPP6R2 9701 RNAseq 0.1196 0.4446
SRP219564 PPP6R2 9701 RNAseq -0.0988 0.6197

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by PPP6R2 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  

Copy number change of PPP6R2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PPP6R2 9701 3 8 19
GSE20123 PPP6R2 9701 3 8 19
GSE43470 PPP6R2 9701 2 8 33
GSE46452 PPP6R2 9701 31 2 26
GSE47630 PPP6R2 9701 9 4 27
GSE54993 PPP6R2 9701 4 6 60
GSE54994 PPP6R2 9701 11 8 34
GSE60625 PPP6R2 9701 5 0 6
GSE74703 PPP6R2 9701 2 6 28
GSE74704 PPP6R2 9701 1 4 15
TCGA PPP6R2 9701 26 16 54

Total number of gains: 97; Total number of losses: 70; Total Number of normals: 321.  

 

Somatic mutations of PPP6R2:

 

Generating mutation plots.

 

Highly correlated genes for PPP6R2:

 

Showing top 20/186 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PPP6R2EXOC30.794252303
PPP6R2ALKBH60.766173303
PPP6R2GCDH0.757977303
PPP6R2TOMM40L0.74688303
PPP6R2TBP0.736496303
PPP6R2ANKRD540.732221303
PPP6R2HSD17B70.730334303
PPP6R2LCMT10.724156303
PPP6R2CBFA2T20.722485303
PPP6R2NOP580.72179303
PPP6R2TTF10.715955303
PPP6R2CHD80.711424404
PPP6R2THOC20.707371303
PPP6R2JOSD20.707219303
PPP6R2LRP5L0.705519303
PPP6R2OXA1L0.703662303
PPP6R2ABHD40.701668404
PPP6R2DYNLL20.700581303
PPP6R2ZNF4080.697866303
PPP6R2CRYBB20.697121303

For details and further investigation, click here