| Full name: spectrin beta, non-erythrocytic 5 | Alias Symbol: HUSPECV|BSPECV|HUBSPECV | ||
| Type: protein-coding gene | Cytoband: 15q21 | ||
| Entrez ID: 51332 | HGNC ID: HGNC:15680 | Ensembl Gene: ENSG00000137877 | OMIM ID: 605916 |
| Drug and gene relationship at DGIdb | |||
Expression of SPTBN5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SPTBN5 | 51332 | 220067_at | 0.0363 | 0.9518 | |
| GSE20347 | SPTBN5 | 51332 | 220067_at | -0.0507 | 0.6600 | |
| GSE23400 | SPTBN5 | 51332 | 220067_at | -0.1989 | 0.0000 | |
| GSE26886 | SPTBN5 | 51332 | 220067_at | -0.0529 | 0.7456 | |
| GSE29001 | SPTBN5 | 51332 | 220067_at | -0.2531 | 0.1241 | |
| GSE38129 | SPTBN5 | 51332 | 220067_at | -0.1708 | 0.2448 | |
| GSE45670 | SPTBN5 | 51332 | 220067_at | 0.1211 | 0.4594 | |
| GSE53622 | SPTBN5 | 51332 | 179091 | -0.5960 | 0.0000 | |
| GSE53624 | SPTBN5 | 51332 | 179091 | -0.5871 | 0.0000 | |
| GSE63941 | SPTBN5 | 51332 | 220067_at | 0.2794 | 0.2424 | |
| GSE77861 | SPTBN5 | 51332 | 220067_at | -0.1107 | 0.2675 | |
| GSE97050 | SPTBN5 | 51332 | A_23_P152082 | 0.0122 | 0.9667 | |
| SRP064894 | SPTBN5 | 51332 | RNAseq | 0.2994 | 0.2421 | |
| SRP133303 | SPTBN5 | 51332 | RNAseq | -0.3724 | 0.3017 | |
| SRP159526 | SPTBN5 | 51332 | RNAseq | -0.8500 | 0.0123 | |
| SRP193095 | SPTBN5 | 51332 | RNAseq | 0.2625 | 0.3328 | |
| SRP219564 | SPTBN5 | 51332 | RNAseq | -0.6735 | 0.1957 | |
| TCGA | SPTBN5 | 51332 | RNAseq | -0.0081 | 0.9669 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SPTBN5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SPTBN5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SPTBN5 | 51332 | 4 | 5 | 21 | |
| GSE20123 | SPTBN5 | 51332 | 4 | 5 | 21 | |
| GSE43470 | SPTBN5 | 51332 | 4 | 5 | 34 | |
| GSE46452 | SPTBN5 | 51332 | 3 | 7 | 49 | |
| GSE47630 | SPTBN5 | 51332 | 8 | 11 | 21 | |
| GSE54993 | SPTBN5 | 51332 | 4 | 6 | 60 | |
| GSE54994 | SPTBN5 | 51332 | 5 | 7 | 41 | |
| GSE60625 | SPTBN5 | 51332 | 4 | 0 | 7 | |
| GSE74703 | SPTBN5 | 51332 | 4 | 4 | 28 | |
| GSE74704 | SPTBN5 | 51332 | 3 | 3 | 14 | |
| TCGA | SPTBN5 | 51332 | 11 | 17 | 68 |
Total number of gains: 54; Total number of losses: 70; Total Number of normals: 364.
Somatic mutations of SPTBN5:
Generating mutation plots.
Highly correlated genes for SPTBN5:
Showing top 20/482 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPTBN5 | TM6SF2 | 0.769798 | 4 | 0 | 3 |
| SPTBN5 | TERT | 0.755897 | 4 | 0 | 4 |
| SPTBN5 | TLR8 | 0.722592 | 3 | 0 | 3 |
| SPTBN5 | GP9 | 0.720758 | 3 | 0 | 3 |
| SPTBN5 | PRKAR1B | 0.719789 | 3 | 0 | 3 |
| SPTBN5 | RASL10A | 0.7197 | 3 | 0 | 3 |
| SPTBN5 | ADM2 | 0.718864 | 4 | 0 | 4 |
| SPTBN5 | CPA5 | 0.713322 | 3 | 0 | 3 |
| SPTBN5 | LMAN1L | 0.697109 | 4 | 0 | 3 |
| SPTBN5 | TSKS | 0.696774 | 4 | 0 | 3 |
| SPTBN5 | DGCR5 | 0.695701 | 3 | 0 | 3 |
| SPTBN5 | AP4B1 | 0.69435 | 3 | 0 | 3 |
| SPTBN5 | SEC14L4 | 0.688579 | 4 | 0 | 3 |
| SPTBN5 | C11orf94 | 0.687405 | 3 | 0 | 3 |
| SPTBN5 | RHAG | 0.687157 | 3 | 0 | 3 |
| SPTBN5 | TRPV5 | 0.687103 | 3 | 0 | 3 |
| SPTBN5 | USP49 | 0.680482 | 4 | 0 | 3 |
| SPTBN5 | S100A5 | 0.680208 | 4 | 0 | 3 |
| SPTBN5 | MUC2 | 0.678273 | 5 | 0 | 4 |
| SPTBN5 | GDF2 | 0.675168 | 4 | 0 | 4 |
For details and further investigation, click here
