| Full name: G protein-coupled receptor 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2q33.3 | ||
| Entrez ID: 2825 | HGNC ID: HGNC:4463 | Ensembl Gene: ENSG00000183671 | OMIM ID: 600239 |
| Drug and gene relationship at DGIdb | |||
Expression of GPR1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPR1 | 2825 | 214605_x_at | -0.0136 | 0.9911 | |
| GSE20347 | GPR1 | 2825 | 214605_x_at | -0.0499 | 0.6894 | |
| GSE23400 | GPR1 | 2825 | 214605_x_at | -0.0386 | 0.1711 | |
| GSE26886 | GPR1 | 2825 | 214605_x_at | -0.1004 | 0.4404 | |
| GSE29001 | GPR1 | 2825 | 214605_x_at | -0.0370 | 0.8297 | |
| GSE38129 | GPR1 | 2825 | 214605_x_at | -0.2219 | 0.1964 | |
| GSE45670 | GPR1 | 2825 | 214605_x_at | 0.1127 | 0.3991 | |
| GSE53622 | GPR1 | 2825 | 24683 | -0.5581 | 0.0089 | |
| GSE53624 | GPR1 | 2825 | 24683 | -0.9075 | 0.0000 | |
| GSE63941 | GPR1 | 2825 | 214605_x_at | -0.9188 | 0.0287 | |
| GSE77861 | GPR1 | 2825 | 214605_x_at | 0.0199 | 0.9649 | |
| SRP007169 | GPR1 | 2825 | RNAseq | -2.9493 | 0.0000 | |
| SRP008496 | GPR1 | 2825 | RNAseq | -2.2705 | 0.0000 | |
| SRP064894 | GPR1 | 2825 | RNAseq | -0.9929 | 0.0002 | |
| SRP133303 | GPR1 | 2825 | RNAseq | -0.2782 | 0.4320 | |
| SRP159526 | GPR1 | 2825 | RNAseq | -2.3596 | 0.0000 | |
| SRP219564 | GPR1 | 2825 | RNAseq | -0.3837 | 0.4121 | |
| TCGA | GPR1 | 2825 | RNAseq | 0.5076 | 0.0842 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by GPR1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPR1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPR1 | 2825 | 3 | 6 | 21 | |
| GSE20123 | GPR1 | 2825 | 3 | 6 | 21 | |
| GSE43470 | GPR1 | 2825 | 1 | 4 | 38 | |
| GSE46452 | GPR1 | 2825 | 1 | 4 | 54 | |
| GSE47630 | GPR1 | 2825 | 4 | 5 | 31 | |
| GSE54993 | GPR1 | 2825 | 0 | 3 | 67 | |
| GSE54994 | GPR1 | 2825 | 8 | 9 | 36 | |
| GSE60625 | GPR1 | 2825 | 0 | 3 | 8 | |
| GSE74703 | GPR1 | 2825 | 1 | 3 | 32 | |
| GSE74704 | GPR1 | 2825 | 2 | 2 | 16 | |
| TCGA | GPR1 | 2825 | 13 | 22 | 61 |
Total number of gains: 36; Total number of losses: 67; Total Number of normals: 385.
Somatic mutations of GPR1:
Generating mutation plots.
Highly correlated genes for GPR1:
Showing top 20/69 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPR1 | OCIAD1 | 0.674553 | 4 | 0 | 3 |
| GPR1 | HAUS2 | 0.670841 | 7 | 0 | 7 |
| GPR1 | UBQLN4 | 0.666525 | 5 | 0 | 5 |
| GPR1 | FUT8-AS1 | 0.662835 | 3 | 0 | 3 |
| GPR1 | UACA | 0.657402 | 4 | 0 | 3 |
| GPR1 | FAM161B | 0.651778 | 5 | 0 | 5 |
| GPR1 | DBT | 0.646429 | 8 | 0 | 8 |
| GPR1 | PGF | 0.645355 | 9 | 0 | 8 |
| GPR1 | SLC35E1 | 0.645343 | 10 | 0 | 8 |
| GPR1 | MBTD1 | 0.641148 | 5 | 0 | 3 |
| GPR1 | ZNF611 | 0.633559 | 9 | 0 | 8 |
| GPR1 | ZNF486 | 0.628726 | 4 | 0 | 4 |
| GPR1 | PRKAR2A | 0.626331 | 4 | 0 | 3 |
| GPR1 | UBE2E2 | 0.625056 | 3 | 0 | 3 |
| GPR1 | SSBP3-AS1 | 0.624583 | 5 | 0 | 4 |
| GPR1 | PODNL1 | 0.620811 | 10 | 0 | 8 |
| GPR1 | DDX51 | 0.61011 | 4 | 0 | 3 |
| GPR1 | DCLRE1C | 0.606218 | 8 | 0 | 6 |
| GPR1 | NEK8 | 0.604777 | 3 | 0 | 3 |
| GPR1 | GTF2H3 | 0.603263 | 8 | 0 | 7 |
For details and further investigation, click here
