| Full name: ubiquitin conjugating enzyme E2 E2 | Alias Symbol: UbcH8|FLJ25157 | ||
| Type: protein-coding gene | Cytoband: 3p24.3 | ||
| Entrez ID: 7325 | HGNC ID: HGNC:12478 | Ensembl Gene: ENSG00000182247 | OMIM ID: 602163 |
| Drug and gene relationship at DGIdb | |||
Expression of UBE2E2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UBE2E2 | 7325 | 225651_at | -0.0707 | 0.8884 | |
| GSE26886 | UBE2E2 | 7325 | 225651_at | -1.2950 | 0.0001 | |
| GSE45670 | UBE2E2 | 7325 | 225651_at | -0.2300 | 0.0855 | |
| GSE53622 | UBE2E2 | 7325 | 109170 | -0.4668 | 0.0001 | |
| GSE53624 | UBE2E2 | 7325 | 109170 | -0.4674 | 0.0065 | |
| GSE63941 | UBE2E2 | 7325 | 225651_at | 0.0015 | 0.9990 | |
| GSE77861 | UBE2E2 | 7325 | 225651_at | -0.7544 | 0.0724 | |
| GSE97050 | UBE2E2 | 7325 | A_32_P155506 | -0.1867 | 0.5183 | |
| SRP007169 | UBE2E2 | 7325 | RNAseq | -1.2293 | 0.0013 | |
| SRP008496 | UBE2E2 | 7325 | RNAseq | -0.8312 | 0.0034 | |
| SRP064894 | UBE2E2 | 7325 | RNAseq | -0.0828 | 0.5674 | |
| SRP133303 | UBE2E2 | 7325 | RNAseq | 0.0571 | 0.6962 | |
| SRP159526 | UBE2E2 | 7325 | RNAseq | -0.4355 | 0.0864 | |
| SRP193095 | UBE2E2 | 7325 | RNAseq | -0.1135 | 0.5039 | |
| SRP219564 | UBE2E2 | 7325 | RNAseq | -0.5175 | 0.1046 | |
| TCGA | UBE2E2 | 7325 | RNAseq | 0.1535 | 0.0591 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by UBE2E2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UBE2E2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UBE2E2 | 7325 | 0 | 18 | 12 | |
| GSE20123 | UBE2E2 | 7325 | 0 | 18 | 12 | |
| GSE43470 | UBE2E2 | 7325 | 0 | 20 | 23 | |
| GSE46452 | UBE2E2 | 7325 | 2 | 17 | 40 | |
| GSE47630 | UBE2E2 | 7325 | 1 | 24 | 15 | |
| GSE54993 | UBE2E2 | 7325 | 6 | 2 | 62 | |
| GSE54994 | UBE2E2 | 7325 | 1 | 32 | 20 | |
| GSE60625 | UBE2E2 | 7325 | 5 | 0 | 6 | |
| GSE74703 | UBE2E2 | 7325 | 0 | 17 | 19 | |
| GSE74704 | UBE2E2 | 7325 | 0 | 12 | 8 | |
| TCGA | UBE2E2 | 7325 | 1 | 68 | 27 |
Total number of gains: 16; Total number of losses: 228; Total Number of normals: 244.
Somatic mutations of UBE2E2:
Generating mutation plots.
Highly correlated genes for UBE2E2:
Showing top 20/567 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UBE2E2 | PPP4R2 | 0.812447 | 3 | 0 | 3 |
| UBE2E2 | ACSL3 | 0.812265 | 3 | 0 | 3 |
| UBE2E2 | PPP2R5E | 0.797265 | 3 | 0 | 3 |
| UBE2E2 | TOX4 | 0.796049 | 3 | 0 | 3 |
| UBE2E2 | TBC1D20 | 0.791319 | 3 | 0 | 3 |
| UBE2E2 | NDUFA10 | 0.769542 | 3 | 0 | 3 |
| UBE2E2 | MCFD2 | 0.763337 | 3 | 0 | 3 |
| UBE2E2 | TRAPPC6B | 0.756216 | 3 | 0 | 3 |
| UBE2E2 | KLHL9 | 0.753307 | 3 | 0 | 3 |
| UBE2E2 | HDHD2 | 0.74907 | 3 | 0 | 3 |
| UBE2E2 | RBM15B | 0.748022 | 3 | 0 | 3 |
| UBE2E2 | SOCS6 | 0.734599 | 3 | 0 | 3 |
| UBE2E2 | ALKBH3 | 0.733517 | 3 | 0 | 3 |
| UBE2E2 | C1GALT1 | 0.732646 | 3 | 0 | 3 |
| UBE2E2 | CDYL | 0.726785 | 3 | 0 | 3 |
| UBE2E2 | DECR1 | 0.725657 | 3 | 0 | 3 |
| UBE2E2 | USP4 | 0.720932 | 4 | 0 | 4 |
| UBE2E2 | PDLIM2 | 0.719943 | 4 | 0 | 3 |
| UBE2E2 | CMTM6 | 0.717758 | 3 | 0 | 3 |
| UBE2E2 | ZNF717 | 0.71401 | 4 | 0 | 3 |
For details and further investigation, click here
