| Full name: G protein-coupled receptor 132 | Alias Symbol: G2A | ||
| Type: protein-coding gene | Cytoband: 14q32.33 | ||
| Entrez ID: 29933 | HGNC ID: HGNC:17482 | Ensembl Gene: ENSG00000183484 | OMIM ID: 606167 |
| Drug and gene relationship at DGIdb | |||
Expression of GPR132:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPR132 | 29933 | 221140_s_at | 0.1184 | 0.7076 | |
| GSE20347 | GPR132 | 29933 | 221140_s_at | -0.0504 | 0.4319 | |
| GSE23400 | GPR132 | 29933 | 221140_s_at | -0.0376 | 0.3215 | |
| GSE26886 | GPR132 | 29933 | 221140_s_at | 0.0817 | 0.5803 | |
| GSE29001 | GPR132 | 29933 | 221140_s_at | -0.0607 | 0.6209 | |
| GSE38129 | GPR132 | 29933 | 221140_s_at | -0.0718 | 0.1403 | |
| GSE45670 | GPR132 | 29933 | 221140_s_at | -0.1153 | 0.1734 | |
| GSE53622 | GPR132 | 29933 | 158893 | 0.3927 | 0.0156 | |
| GSE53624 | GPR132 | 29933 | 3889 | 0.2456 | 0.0831 | |
| GSE63941 | GPR132 | 29933 | 221140_s_at | 0.2358 | 0.4076 | |
| GSE77861 | GPR132 | 29933 | 221140_s_at | -0.1507 | 0.3402 | |
| GSE97050 | GPR132 | 29933 | A_23_P128808 | 0.3470 | 0.1814 | |
| SRP007169 | GPR132 | 29933 | RNAseq | 0.9109 | 0.2143 | |
| SRP064894 | GPR132 | 29933 | RNAseq | 0.4134 | 0.1075 | |
| SRP133303 | GPR132 | 29933 | RNAseq | -0.0490 | 0.7853 | |
| SRP159526 | GPR132 | 29933 | RNAseq | -0.3900 | 0.5444 | |
| SRP193095 | GPR132 | 29933 | RNAseq | 0.4202 | 0.0112 | |
| SRP219564 | GPR132 | 29933 | RNAseq | 1.2608 | 0.0105 | |
| TCGA | GPR132 | 29933 | RNAseq | 0.0552 | 0.7551 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by GPR132 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPR132:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPR132 | 29933 | 11 | 3 | 16 | |
| GSE20123 | GPR132 | 29933 | 10 | 2 | 18 | |
| GSE43470 | GPR132 | 29933 | 6 | 3 | 34 | |
| GSE46452 | GPR132 | 29933 | 18 | 4 | 37 | |
| GSE47630 | GPR132 | 29933 | 10 | 8 | 22 | |
| GSE54993 | GPR132 | 29933 | 4 | 10 | 56 | |
| GSE54994 | GPR132 | 29933 | 21 | 4 | 28 | |
| GSE60625 | GPR132 | 29933 | 0 | 2 | 9 | |
| GSE74703 | GPR132 | 29933 | 5 | 3 | 28 | |
| GSE74704 | GPR132 | 29933 | 5 | 2 | 13 | |
| TCGA | GPR132 | 29933 | 32 | 17 | 47 |
Total number of gains: 122; Total number of losses: 58; Total Number of normals: 308.
Somatic mutations of GPR132:
Generating mutation plots.
Highly correlated genes for GPR132:
Showing top 20/520 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPR132 | PRELID1 | 0.831102 | 3 | 0 | 3 |
| GPR132 | DNAJB12 | 0.783252 | 3 | 0 | 3 |
| GPR132 | JOSD2 | 0.757617 | 3 | 0 | 3 |
| GPR132 | BTBD6 | 0.756407 | 3 | 0 | 3 |
| GPR132 | UNK | 0.756353 | 3 | 0 | 3 |
| GPR132 | AOAH | 0.75432 | 4 | 0 | 4 |
| GPR132 | GRIN3B | 0.751284 | 3 | 0 | 3 |
| GPR132 | UBE2O | 0.749774 | 3 | 0 | 3 |
| GPR132 | PLEKHA4 | 0.740681 | 3 | 0 | 3 |
| GPR132 | RNF187 | 0.740441 | 3 | 0 | 3 |
| GPR132 | TP53I11 | 0.740435 | 3 | 0 | 3 |
| GPR132 | CD163L1 | 0.738579 | 4 | 0 | 4 |
| GPR132 | RNF31 | 0.736919 | 3 | 0 | 3 |
| GPR132 | MYO1F | 0.735507 | 5 | 0 | 5 |
| GPR132 | GTPBP2 | 0.733289 | 3 | 0 | 3 |
| GPR132 | RGS18 | 0.729861 | 4 | 0 | 4 |
| GPR132 | LCP2 | 0.727559 | 4 | 0 | 4 |
| GPR132 | C19orf38 | 0.726941 | 3 | 0 | 3 |
| GPR132 | MUL1 | 0.720986 | 3 | 0 | 3 |
| GPR132 | ZMIZ2 | 0.719861 | 3 | 0 | 3 |
For details and further investigation, click here
