| Full name: acyloxyacyl hydrolase | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 7p14.2 | ||
| Entrez ID: 313 | HGNC ID: HGNC:548 | Ensembl Gene: ENSG00000136250 | OMIM ID: 102593 |
| Drug and gene relationship at DGIdb | |||
Expression of AOAH:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AOAH | 313 | 205639_at | -0.0219 | 0.9830 | |
| GSE20347 | AOAH | 313 | 205639_at | 0.1638 | 0.1209 | |
| GSE23400 | AOAH | 313 | 205639_at | 0.0765 | 0.0776 | |
| GSE26886 | AOAH | 313 | 205639_at | -0.0135 | 0.9533 | |
| GSE29001 | AOAH | 313 | 205639_at | 0.3293 | 0.2171 | |
| GSE38129 | AOAH | 313 | 205639_at | 0.0724 | 0.5409 | |
| GSE45670 | AOAH | 313 | 205639_at | -0.0598 | 0.8205 | |
| GSE53622 | AOAH | 313 | 30333 | -0.0667 | 0.7441 | |
| GSE53624 | AOAH | 313 | 30333 | -0.0818 | 0.7477 | |
| GSE63941 | AOAH | 313 | 205639_at | 0.0962 | 0.5462 | |
| GSE77861 | AOAH | 313 | 205639_at | 0.0284 | 0.8734 | |
| GSE97050 | AOAH | 313 | A_23_P145718 | 0.3792 | 0.1939 | |
| SRP007169 | AOAH | 313 | RNAseq | 4.0997 | 0.0000 | |
| SRP008496 | AOAH | 313 | RNAseq | 2.8068 | 0.0024 | |
| SRP064894 | AOAH | 313 | RNAseq | 1.1385 | 0.0025 | |
| SRP133303 | AOAH | 313 | RNAseq | -0.1020 | 0.7497 | |
| SRP159526 | AOAH | 313 | RNAseq | 1.8173 | 0.0592 | |
| SRP193095 | AOAH | 313 | RNAseq | -0.0308 | 0.9008 | |
| SRP219564 | AOAH | 313 | RNAseq | 1.0698 | 0.0727 | |
| TCGA | AOAH | 313 | RNAseq | 0.3768 | 0.1421 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by AOAH expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AOAH:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AOAH | 313 | 16 | 0 | 14 | |
| GSE20123 | AOAH | 313 | 16 | 0 | 14 | |
| GSE43470 | AOAH | 313 | 4 | 0 | 39 | |
| GSE46452 | AOAH | 313 | 11 | 1 | 47 | |
| GSE47630 | AOAH | 313 | 8 | 1 | 31 | |
| GSE54993 | AOAH | 313 | 0 | 7 | 63 | |
| GSE54994 | AOAH | 313 | 18 | 3 | 32 | |
| GSE60625 | AOAH | 313 | 0 | 0 | 11 | |
| GSE74703 | AOAH | 313 | 4 | 0 | 32 | |
| GSE74704 | AOAH | 313 | 9 | 0 | 11 | |
| TCGA | AOAH | 313 | 53 | 6 | 37 |
Total number of gains: 139; Total number of losses: 18; Total Number of normals: 331.
Somatic mutations of AOAH:
Generating mutation plots.
Highly correlated genes for AOAH:
Showing top 20/356 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AOAH | GIMAP5 | 0.782234 | 3 | 0 | 3 |
| AOAH | GPR132 | 0.75432 | 4 | 0 | 4 |
| AOAH | C19orf38 | 0.752808 | 3 | 0 | 3 |
| AOAH | PLCB2 | 0.750703 | 4 | 0 | 4 |
| AOAH | TNFAIP8L2 | 0.745495 | 6 | 0 | 5 |
| AOAH | CYSLTR2 | 0.737136 | 4 | 0 | 4 |
| AOAH | GAPT | 0.736658 | 4 | 0 | 4 |
| AOAH | TNFSF8 | 0.734993 | 4 | 0 | 4 |
| AOAH | TNFSF13 | 0.720248 | 3 | 0 | 3 |
| AOAH | CDC42SE2 | 0.719226 | 4 | 0 | 4 |
| AOAH | SELL | 0.707482 | 7 | 0 | 7 |
| AOAH | EBI3 | 0.706615 | 4 | 0 | 3 |
| AOAH | PHACTR1 | 0.703183 | 4 | 0 | 3 |
| AOAH | IRF8 | 0.702547 | 9 | 0 | 8 |
| AOAH | SULT1C2 | 0.700434 | 3 | 0 | 3 |
| AOAH | GPR141 | 0.699938 | 3 | 0 | 3 |
| AOAH | CXCR5 | 0.699916 | 3 | 0 | 3 |
| AOAH | CORO1A | 0.693005 | 9 | 0 | 9 |
| AOAH | PARP15 | 0.69062 | 3 | 0 | 3 |
| AOAH | DGKD | 0.689989 | 3 | 0 | 3 |
For details and further investigation, click here
