| Full name: Josephin domain containing 2 | Alias Symbol: SBBI54 | ||
| Type: protein-coding gene | Cytoband: 19q13.33 | ||
| Entrez ID: 126119 | HGNC ID: HGNC:28853 | Ensembl Gene: ENSG00000161677 | OMIM ID: 615324 |
| Drug and gene relationship at DGIdb | |||
Expression of JOSD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | JOSD2 | 126119 | 227096_at | -0.0754 | 0.8009 | |
| GSE26886 | JOSD2 | 126119 | 227096_at | 0.0226 | 0.9074 | |
| GSE45670 | JOSD2 | 126119 | 227096_at | 0.1642 | 0.0289 | |
| GSE53622 | JOSD2 | 126119 | 77691 | 0.0635 | 0.3226 | |
| GSE53624 | JOSD2 | 126119 | 77691 | -0.0813 | 0.6048 | |
| GSE63941 | JOSD2 | 126119 | 227096_at | 0.4013 | 0.1648 | |
| GSE77861 | JOSD2 | 126119 | 227096_at | -0.1146 | 0.6464 | |
| GSE97050 | JOSD2 | 126119 | A_33_P3220929 | 0.0236 | 0.9137 | |
| SRP007169 | JOSD2 | 126119 | RNAseq | -1.2749 | 0.0029 | |
| SRP008496 | JOSD2 | 126119 | RNAseq | -1.0001 | 0.0002 | |
| SRP064894 | JOSD2 | 126119 | RNAseq | 1.2295 | 0.0062 | |
| SRP133303 | JOSD2 | 126119 | RNAseq | 0.0633 | 0.7510 | |
| SRP159526 | JOSD2 | 126119 | RNAseq | -0.0554 | 0.7683 | |
| SRP193095 | JOSD2 | 126119 | RNAseq | -0.3709 | 0.0103 | |
| SRP219564 | JOSD2 | 126119 | RNAseq | 0.2691 | 0.4913 | |
| TCGA | JOSD2 | 126119 | RNAseq | 0.0096 | 0.9027 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by JOSD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of JOSD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | JOSD2 | 126119 | 3 | 4 | 23 | |
| GSE20123 | JOSD2 | 126119 | 3 | 3 | 24 | |
| GSE43470 | JOSD2 | 126119 | 4 | 11 | 28 | |
| GSE46452 | JOSD2 | 126119 | 45 | 1 | 13 | |
| GSE47630 | JOSD2 | 126119 | 10 | 6 | 24 | |
| GSE54993 | JOSD2 | 126119 | 17 | 4 | 49 | |
| GSE54994 | JOSD2 | 126119 | 4 | 14 | 35 | |
| GSE60625 | JOSD2 | 126119 | 9 | 0 | 2 | |
| GSE74703 | JOSD2 | 126119 | 4 | 7 | 25 | |
| GSE74704 | JOSD2 | 126119 | 3 | 1 | 16 | |
| TCGA | JOSD2 | 126119 | 14 | 19 | 63 |
Total number of gains: 116; Total number of losses: 70; Total Number of normals: 302.
Somatic mutations of JOSD2:
Generating mutation plots.
Highly correlated genes for JOSD2:
Showing top 20/180 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| JOSD2 | KRTAP19-2 | 0.826055 | 3 | 0 | 3 |
| JOSD2 | CIDEB | 0.781339 | 3 | 0 | 3 |
| JOSD2 | PFKL | 0.781119 | 3 | 0 | 3 |
| JOSD2 | ABHD4 | 0.780931 | 3 | 0 | 3 |
| JOSD2 | ITPKC | 0.770687 | 3 | 0 | 3 |
| JOSD2 | GPR132 | 0.757617 | 3 | 0 | 3 |
| JOSD2 | LDB1 | 0.731175 | 3 | 0 | 3 |
| JOSD2 | TINF2 | 0.7246 | 3 | 0 | 3 |
| JOSD2 | ENTPD2 | 0.722412 | 5 | 0 | 5 |
| JOSD2 | TMEM38A | 0.719502 | 4 | 0 | 4 |
| JOSD2 | CNP | 0.712963 | 3 | 0 | 3 |
| JOSD2 | ACTB | 0.711793 | 3 | 0 | 3 |
| JOSD2 | SEMA4A | 0.711139 | 3 | 0 | 3 |
| JOSD2 | PPP6R2 | 0.707219 | 3 | 0 | 3 |
| JOSD2 | NDFIP1 | 0.705437 | 4 | 0 | 4 |
| JOSD2 | FAM167B | 0.705029 | 3 | 0 | 3 |
| JOSD2 | TBCA | 0.699405 | 3 | 0 | 3 |
| JOSD2 | APOB | 0.699157 | 4 | 0 | 3 |
| JOSD2 | CMIP | 0.697066 | 3 | 0 | 3 |
| JOSD2 | DOT1L | 0.695262 | 4 | 0 | 4 |
For details and further investigation, click here
