| Full name: G protein-coupled receptor 180 | Alias Symbol: ITR | ||
| Type: protein-coding gene | Cytoband: 13q32.1 | ||
| Entrez ID: 160897 | HGNC ID: HGNC:28899 | Ensembl Gene: ENSG00000152749 | OMIM ID: 607787 |
| Drug and gene relationship at DGIdb | |||
Expression of GPR180:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPR180 | 160897 | 231871_at | 0.9577 | 0.0253 | |
| GSE26886 | GPR180 | 160897 | 231871_at | 0.9789 | 0.0051 | |
| GSE45670 | GPR180 | 160897 | 231871_at | 0.8103 | 0.0015 | |
| GSE53622 | GPR180 | 160897 | 7084 | 0.5676 | 0.0000 | |
| GSE53624 | GPR180 | 160897 | 7084 | 0.7105 | 0.0000 | |
| GSE63941 | GPR180 | 160897 | 231871_at | -0.1677 | 0.7326 | |
| GSE77861 | GPR180 | 160897 | 232912_at | 0.1387 | 0.2928 | |
| GSE97050 | GPR180 | 160897 | A_33_P3666797 | 0.1130 | 0.5913 | |
| SRP007169 | GPR180 | 160897 | RNAseq | 1.3286 | 0.0066 | |
| SRP008496 | GPR180 | 160897 | RNAseq | 1.2223 | 0.0001 | |
| SRP064894 | GPR180 | 160897 | RNAseq | 1.1731 | 0.0000 | |
| SRP133303 | GPR180 | 160897 | RNAseq | 1.0576 | 0.0000 | |
| SRP159526 | GPR180 | 160897 | RNAseq | 0.3596 | 0.1351 | |
| SRP193095 | GPR180 | 160897 | RNAseq | 0.2992 | 0.0619 | |
| SRP219564 | GPR180 | 160897 | RNAseq | 0.9776 | 0.0387 | |
| TCGA | GPR180 | 160897 | RNAseq | 0.1361 | 0.0331 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by GPR180 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPR180:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPR180 | 160897 | 4 | 9 | 17 | |
| GSE20123 | GPR180 | 160897 | 4 | 8 | 18 | |
| GSE43470 | GPR180 | 160897 | 2 | 12 | 29 | |
| GSE46452 | GPR180 | 160897 | 0 | 32 | 27 | |
| GSE47630 | GPR180 | 160897 | 3 | 27 | 10 | |
| GSE54993 | GPR180 | 160897 | 11 | 3 | 56 | |
| GSE54994 | GPR180 | 160897 | 3 | 14 | 36 | |
| GSE60625 | GPR180 | 160897 | 0 | 3 | 8 | |
| GSE74703 | GPR180 | 160897 | 2 | 10 | 24 | |
| GSE74704 | GPR180 | 160897 | 2 | 8 | 10 | |
| TCGA | GPR180 | 160897 | 14 | 33 | 49 |
Total number of gains: 45; Total number of losses: 159; Total Number of normals: 284.
Somatic mutations of GPR180:
Generating mutation plots.
Highly correlated genes for GPR180:
Showing top 20/337 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPR180 | MAK | 0.778671 | 3 | 0 | 3 |
| GPR180 | ZNF77 | 0.776542 | 3 | 0 | 3 |
| GPR180 | SLC2A6 | 0.765943 | 3 | 0 | 3 |
| GPR180 | RECQL4 | 0.733578 | 3 | 0 | 3 |
| GPR180 | MED20 | 0.733466 | 4 | 0 | 4 |
| GPR180 | FLAD1 | 0.729478 | 3 | 0 | 3 |
| GPR180 | LFNG | 0.724792 | 3 | 0 | 3 |
| GPR180 | NUP62CL | 0.714986 | 4 | 0 | 3 |
| GPR180 | MTERF3 | 0.714313 | 4 | 0 | 4 |
| GPR180 | LCORL | 0.709261 | 3 | 0 | 3 |
| GPR180 | KIF4A | 0.706721 | 5 | 0 | 4 |
| GPR180 | RBM28 | 0.703981 | 5 | 0 | 4 |
| GPR180 | POLR3A | 0.698616 | 4 | 0 | 3 |
| GPR180 | NOC4L | 0.698349 | 4 | 0 | 4 |
| GPR180 | JPH1 | 0.69827 | 3 | 0 | 3 |
| GPR180 | GTF2IRD2 | 0.697358 | 4 | 0 | 3 |
| GPR180 | FAM24B | 0.697335 | 4 | 0 | 3 |
| GPR180 | TIMM22 | 0.69729 | 3 | 0 | 3 |
| GPR180 | ZNF639 | 0.695371 | 4 | 0 | 4 |
| GPR180 | TMEM177 | 0.693903 | 5 | 0 | 5 |
For details and further investigation, click here
